CAS 1337531-89-1

Formula: C24H19F4N5O

InChI: InChI=1S/C24H19F4N5O/c1-32-11-18(21-22(29)30-12-31-23(21)32)14-2-3-19-15(9-14)4-5-33(19)20(34)8-13-6-16(24(26,27)28)10-17(25)7-13/h2-3,6-7,9-12H,4-5,8H2,1H3,(H2,29,30,31)

InChI key: PXVQGBJMIQCDEX-UHFFFAOYSA-N

SMILES: CN1C=C(C2=C(N=CN=C21)N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC(=C5)F)C(F)(F)F

1-(5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-fluoro-5-(trifluoromethyl)phenyl)ethan-1-one

CAS: 1337531-89-1

Formula: C₂₄H₁₉F₄N₅O

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 469.4342

Ref: IN-DA009ET4

PERK-IN-4

CAS: 1337531-89-1

PERK-IN-4

Formula: C₂₄H₁₉F₄N₅O

Purezza: ≥98%

Peso molecolare: 469.43

Ref: 54-BUP07493

PERK-IN-4

CAS: 1337531-89-1

PERK-IN-4 is a potent and selective PERK inhibitor with an IC50 value of 0.3 nM.PERK-IN-4 can be used in the study of cancer and neurological disorders.

Formula: C₂₄H₁₉F₄N₅O

Purezza: 99.44% - 99.49%

Colore e forma: Solid

Peso molecolare: 469.43

Ref: TM-T38732

GSK PERK Inhibitor

Prodotto controllato

CAS: 1337531-89-1

Applications GSK PERK Inhibitor is an inhibitor of PERK, an important transmembrane protein of endoplasmic reticulum (ER). GSK PERK Inhibitor can be useful in the treatment of cancer, ocular diseases, and diseases associated with activated unfolded protein response pathways. As a result, GSK PERK Inhibitor has potential use in the treatment of diseases such as Alzheimer's disease, stroke, Type 1 diabetes, Parkinson disease, Huntington's disease, amyotrophic lateral sclerosis, myocardial infarction, cardiovascular disease, atherosclerosis, and arrhythmias, and more specifically cancers of the breast, colon, pancreatic, and lung.
References Baltzis, D. et al.: J. Biol. Chem., 282, 31675 (2007); Axten, J. M.et al,: J. Med. Chem. 55(16) 7193 (2012).

Formula: C₂₄H₁₉F₄N₅O

Colore e forma: Neat

Peso molecolare: 469.43

Ref: TR-G797800

GSK PERK Inhibitor-d3

Prodotto controllato

CAS: 1337531-89-1

Formula: C₂₄D₃H₁₆F₄N₅O

Colore e forma: Neat

Peso molecolare: 472.453

Ref: TR-G797802

GSK PERK inhibitor

CAS: 1337531-89-1

Inhibitor of EIF2AK3/PERK kinases

Formula: C₂₄H₁₉F₄N₅O

Purezza: Min. 95%

Peso molecolare: 469.43 g/mol

Ref: 3D-FG23705