CAS 138844-81-2: Ibandronato sodico

Descrizione: Ibandronato sodico è un composto di bisfosfonato utilizzato principalmente nel trattamento e nella prevenzione dell'osteoporosi, in particolare nelle donne in postmenopausa. Funziona inibendo la riassorbimento osseo mediato dagli osteoclasti, aumentando così la densità minerale ossea e riducendo il rischio di fratture. La sostanza è caratterizzata dalla sua alta affinità per l'idrossiapatite, che le consente di legarsi efficacemente al tessuto osseo. Ibandronato sodico viene tipicamente somministrato per via orale o endovenosa, con la sua farmacocinetica influenzata da fattori come l'assunzione di cibo e la funzione renale. Il composto è noto per la sua relativamente lunga emivita nell'osso, consentendo una somministrazione meno frequente rispetto ad altri bisfosfonati. Gli effetti collaterali comuni possono includere disturbi gastrointestinali, dolore muscoloscheletrico e, in rari casi, osteonecrosi della mandibola. A causa del suo meccanismo d'azione, Ibandronato sodico è anche oggetto di indagine per potenziali applicazioni in altre condizioni che coinvolgono il metabolismo osseo. Come con qualsiasi farmaco, è essenziale considerare controindicazioni e interazioni con altri farmaci quando si prescrive o si utilizza questo composto.

Formula: C₉H₂₃NO₇P₂·Na

InChI: InChI=1S/C9H23NO7P2.Na/c1-3-4-5-7-10(2)8-6-9(11,18(12,13)14)19(15,16)17;/h11H,3-8H2,1-2H3,(H2,12,13,14)(H2,15,16,17);

InChI key: InChIKey=WQVSHLXLXKMYEW-UHFFFAOYSA-N

SMILES: [Na].O=P(O)(O)C(O)(CCN(C)CCCCC)P(=O)(O)O

Sinonimi:

• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• BM 21.0955Na
• Bm 21.0955
• Bondronat
• Bondronat, (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid sodium
• Bondronate
• Boniva
• Bonviva
• Ibandronate sodium
• Phosphonic acid, P,P′-[1-hydroxy-3-(methylpentylamino)propylidene]bis-, sodium salt (1:1)
• Phosphonic acid, [1-hydroxy-3-(methylpentylamino)propylidene]bis-, monosodium salt
• Sodium Hydrogen {1-Hydroxy-3-[Methyl(Pentyl)Amino]-1-Phosphonopropyl}Phosphonate
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• Ibandronate Sodium (anhydrous)
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt

Ibandronate sodium

CAS: 138844-81-2

Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.

• Formula: C₉H₂₂NNaO₇P₂
• Purezza: 98% - 98.13%
• Colore e forma: Solid
• Peso molecolare: 341.21

Phosphonic acid, P,P'-[1-hydroxy-3-(methylpentylamino)propylidene]bis-, sodium salt (1:1)

CAS: 138844-81-2

• Formula: C₉H₂₂NNaO₇P₂
• Purezza: 90%
• Colore e forma: Solid
• Peso molecolare: 341.2108

Ibandronate Sodium Salt

CAS: 138844-81-2

• Formula: C₉H₂₂NO₇P₂·Na
• Colore e forma: White To Off-White Solid
• Peso molecolare: 318.23 22.99

Sodium Ibandronate

CAS: 114084-78-5 138844-81-2

• Formula: C₉H₂₂NNaO₇P₂
• Purezza: >90.0%(T)
• Colore e forma: White to Almost white powder to crystal
• Peso molecolare: 341.21

Ibandronate Sodium Salt

CAS: 138844-81-2

Applications Ibandronate Sodium Salt is an inhibitor of farnesyl diphosphate synthase. References 1. Han, J. …

• Formula: C₉H₂₂NO₇P₂·Na
• Colore e forma: Off-White
• Peso molecolare: 341.211

Ibandronate sodium

CAS: 138844-81-2

Farnesyl pyrophosphate synthase inhibitor

• Formula: C₉H₂₂NNaO₇P₂
• Purezza: Min. 95%
• Colore e forma: White To Off-White Solid
• Peso molecolare: 341.21 g/mol