CAS 139481-59-7: Candesartan

Descrizione: Candesartan è un antagonista del recettore dell'angiotensina II utilizzato principalmente nel trattamento dell'ipertensione e dell'insufficienza cardiaca. Appartiene alla classe di farmaci noti come sartani, che agiscono bloccando l'azione dell'angiotensina II, un ormone che restringe i vasi sanguigni e aumenta la pressione sanguigna. La formula chimica di Candesartan è C24H20N6O3 e presenta una struttura a bifenile con un anello di tetrazolo, contribuendo alle sue proprietà farmacologiche. Candesartan viene tipicamente somministrato per via orale ed è noto per la sua lunga emivita, che consente una somministrazione una volta al giorno. Viene ben assorbito nel tratto gastrointestinale, sebbene la sua biodisponibilità possa essere influenzata dall'assunzione di cibo. Gli effetti collaterali comuni possono includere vertigini, affaticamento e ipotensione, mentre effetti avversi gravi possono coinvolgere compromissione renale e iperkaliemia. Candesartan è controindicato in gravidanza a causa del potenziale danno al feto. In generale, è un farmaco efficace per gestire l'ipertensione e migliorare gli esiti cardiovascolari nei pazienti con insufficienza cardiaca.

Formula: C₂₄H₂₀N₆O₃

InChI: InChI=1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)

InChI key: InChIKey=HTQMVQVXFRQIKW-UHFFFAOYSA-N

SMILES: O=C(O)C1=CC=CC=2N=C(OCC)N(C21)CC=3C=CC(=CC3)C=4C=CC=CC4C5=NN=NN5

Sinonimi:

• (1,1'-biphenyl)-4-yl)methyl)-
• (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• 1-((2′-(1H-Tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid
• 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate
• 1H-Benzimidazole-7-carboxylic acid
• 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
• 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
• 2-Ethoxy-1-([4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl)-1H-1,3-benzodiazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]-7-benzimidazolecarboxylic acid
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazol-7-carboxylic acid
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid
• 2-Ethoxy-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid
• 2-Ethoxy-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]-3H-benzoimidazole-4-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• 2-ethoxy-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid
• 3-[[2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-ethoxy-3H-benzimidazole-4-carboxylic acid
• Blopress
• Blopress (TN)
• C07468
• Candesartan (USAN)
• Candesartan M1
• Candesartan [USAN:INN]
• Chebi:3347
• Cv 11974
• D00522
• imidazole-7-carboxylic acid
• lic acid

Candesartan, 98%

CAS: 139481-59-7

Candesartan is a selective AT1 (angiotensin II receptor 1) antagonist. Antagonism of angiotensin receptors inhibits …

• Formula: C₂₄H₂₀N₆O₃
• Purezza: 98%
• Colore e forma: Powder, White to pale cream
• Peso molecolare: 440.45

Candesartan Cilexetil Related Compound G (1-{[2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl}-2-ethoxybenzimidazole-7-carboxylic acid)

CAS: 139481-59-7

Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

• Formula: C₂₄H₂₀N₆O₃
• Colore e forma: White Powder
• Peso molecolare: 440.15969

Candesartan

CAS: 139481-59-7

Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of …

• Formula: C₂₄H₂₀N₆O₃
• Purezza: 98.30% - 99.55%
• Colore e forma: Colorless Solid Crystalline
• Peso molecolare: 440.47

Candesartan

CAS: 139481-59-7

• Formula: C₂₄H₂₀N₆O₃
• Purezza: 95%
• Colore e forma: Solid
• Peso molecolare: 440.454

Candesartan (Candesartan Cilexetil EP Impurity G, Candesartan Cilexetil USP Related Compound G)

CAS: 139481-59-7

• Formula: C₂₄H₂₀N₆O₃
• Colore e forma: White To Off-White Solid
• Peso molecolare: 440.46

Candesartan

CAS: 139481-59-7

• Formula: C₂₄H₂₀N₆O₃
• Peso molecolare: 440.45

2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid (Candesartan)

CAS: 139481-59-7

• Formula: C₂₄H₂₀N₆O₃
• Colore e forma: Neat
• Peso molecolare: 440.45

Candesartan 100 µg/mL in Acetonitrile:Methanol

CAS: 139481-59-7

• Formula: C₂₄H₂₀N₆O₃
• Colore e forma: Single Solution
• Peso molecolare: 440.45

Candesartan

CAS: 139481-59-7

• Formula: C₂₄H₂₀N₆O₃
• Colore e forma: Neat
• Peso molecolare: 440.45

Candesartan

CAS: 139481-59-7

Impurity Candesartan Cilexetil EP Impurity G Applications Candesartan (Candesartan Cilexetil EP Impurity G) is an …

• Formula: C₂₄H₂₀N₆O₃
• Colore e forma: Off White
• Peso molecolare: 440.45

Candesartan - Bio-X ™

CAS: 139481-59-7

Candesartan is a drug that belongs to the class of angiotensin II receptor antagonists and …

• Formula: C₂₄H₂₀N₆O₃
• Purezza: Min. 95%
• Colore e forma: Powder
• Peso molecolare: 440.45 g/mol

Candesartan

CAS: 139481-59-7

Angiotensin II receptor I antagonist; anti-hypertensive

• Formula: C₂₄H₂₀N₆O₃
• Purezza: Min. 98 Area-%
• Colore e forma: White Powder
• Peso molecolare: 440.46 g/mol