CAS 1402818-99-8

Formula: C17H11Br2FO3

InChI: InChI=1S/C17H11Br2FO3/c1-2-13-15(10-4-3-9(20)7-14(10)23-13)16(21)8-5-11(18)17(22)12(19)6-8/h3-7,22H,2H2,1H3

InChI key: GIVTUZFBWDBWTM-UHFFFAOYSA-N

SMILES: CCC1=C(C2=C(O1)C=C(C=C2)F)C(=O)C3=CC(=C(C(=C3)Br)O)Br

hURAT1 inhibitor 2

CAS: 1402818-99-8

hURAT1 inhibitor 2 (Compound 5) is an inhibitor of hURAT1 (uric acid transporter 1, SLC22A12) with an IC50 of 18 nM. It also exhibits some inhibitory activity against OATP1B1, with an IC50 of 0.73 μM. hURAT1 inhibitor 2 can be used in research related to hyperuricemia, gout, and other diseases associated with abnormal uric acid metabolism.

Formula: C₁₇H₁₁Br₂FO₃

Colore e forma: Solid

Peso molecolare: 442.074

Ref: TM-T206558