CAS 145100-51-2

N-(5-cloro-2-piridil)bis(trifluorometansulfonimide)

Descrizione:

N-(5-cloro-2-piridil)bis(trifluorometanosulfonamide), con il numero CAS 145100-51-2, è un composto chimico caratterizzato dalla sua struttura unica, che include un anello di piridina sostituito da un atomo di cloro e due gruppi trifluorometanosulfonamide. Questo composto è tipicamente un solido a temperatura ambiente ed è noto per la sua alta stabilità termica e solubilità in solventi organici polari. La presenza di gruppi trifluorometanosulfonamide conferisce una forte acidità e lo rende un potente elettrofilo, che può essere utilizzato in varie reazioni chimiche, comprese le sostituzioni nucleofile e come reagente nella sintesi organica. Inoltre, il sostituente cloruro sull'anello di piridina può influenzare la reattività del composto e la sua interazione con altre specie chimiche. Grazie alle sue proprietà, questo composto può trovare applicazioni in prodotti farmaceutici, agrochimici e scienza dei materiali, in particolare nello sviluppo di liquidi ionici e come catalizzatore nelle trasformazioni organiche. Devono essere osservate precauzioni di sicurezza quando si maneggia questo composto, poiché può comportare rischi per la salute.

Formula: C₇H₃ClF₆N₂O₄S₂

InChI: InChI=1S/C7H3ClF6N2O4S2/c8-4-1-2-5(15-3-4)16(21(17,18)6(9,10)11)22(19,20)7(12,13)14/h1-3H

InChI key: InChIKey=TUFGVZMNGTYAQD-UHFFFAOYSA-N

SMILES: N(S(C(F)(F)F)(=O)=O)(S(C(F)(F)F)(=O)=O)C1=CC=C(Cl)C=N1

Sinonimi:

• 1-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine
• 2-[N,N-Bis(Trifluoromethanesulfonyl)Amino]-5-Chloropyridine
• 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine
• 2-[N,N-Bis(trifluoromethanesulphonyl)amino]-5-chloropyridine
• 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine
• Bistrifluoromethylsulfonylaminochloropyridine
• Comins
• Comins' reagent
• Methanesulfonamide, N-(5-chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]-
• N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridinamine
• N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridylamine
• N-(5-Chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamide
• N-(5-Chloro-2-pyridyl)-N-(trifluoromethanesulfonyl)trifluoromethanesulfonamide
• N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide)
• N-(5-Chloro-2-pyridyl)triflimide
• N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamide
• NSC 683533
• N-(5-CHLORO-2-PYRIDYL)BIS(TRILFUOROMETHANESULFONIMIDE)
• 2-[N,N-bis(trifluoromethylsulphony)amino]-5-chloropyridine
• n-(5-chloro-2-pyridyl)bis(trifluoromethanesulfonyl)imide
• 2-N,N-Bis(trifluoromethanesulfonyl)aminoü-5-chloropyridine, 99%
• N-(5-chloro-2-pyridyl)bis(trifluromethanesulfonimide
• 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine [Triflating Reagent]
• Comins Reagent, N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridylamine, 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine

2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine [Triflating Reagent]

CAS: 145100-51-2

Formula: C₇H₃ClF₆N₂O₄S₂

Purezza: >96.0%(GC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 392.67

Ref: 3B-B1865

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine, 99%

CAS: 145100-51-2

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine provides good yields of vinyl triflates from the corresponding ketone enolates or dienolates. It is used in the total synthesis of (-)-porantheridine and the trans decahydroquinoline alkaloid (+)-219A. It is also used as a reactant for Suzuk

Formula: C₇H₃ClF₆N₂O₄S₂

Purezza: 99%

Colore e forma: White to pale yellow or cream, Crystalline powder

Peso molecolare: 392.67

Ref: 02-L16929

Methanesulfonamide, N-(5-chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]-

CAS: 145100-51-2

Formula: C₇H₃ClF₆N₂O₄S₂

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 392.6831

Ref: IN-DA001KJZ

2-{Bis[(trifluoromethyl)sulphonyl]amino}-5-chloropyridine

CAS: 145100-51-2

2-{Bis[(trifluoromethyl)sulphonyl]amino}-5-chloropyridine

Formula: C₇H₃ClF₆N₂O₄S₂

Purezza: ≥95%

Colore e forma: Off-white Solid

Peso molecolare: 392.68313

Ref: 54-PC3128

N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide)

CAS: 145100-51-2

Formula: C₇H₃ClF₆N₂O₄S₂

Purezza: ≥ 98.0%

Colore e forma: White to orange or brown powder or solid

Peso molecolare: 392.68

Ref: 7W-GX3787

Comin's reagent

CAS: 145100-51-2

Comin's reagent is a sulfonation agent that reacts with an enolate and forms a sulfonic acid. The reaction can be used to synthesize chiral compounds. Comin's reagent is selective for the (R) configuration of acetylcholine and can be used to synthesize α-amino acids from chiral alcohols and esters. Comin's reagent is also used in the synthesis of neurotrophic or growth factor compounds, which are proteins that promote cell growth or differentiation. These functional groups are found in natural products such as nicotinic acetylcholine, thallusin, and growth factor.

Formula: C₇H₃ClF₆N₂O₄S₂

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 392.68 g/mol

Ref: 3D-FC10786

2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine

CAS: 145100-51-2

2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine

Formula: C₇H₃ClF₆N₂O₄S₂

Purezza: 98%

Peso molecolare: 392.68

Ref: IN-DG4062

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine

CAS: 145100-51-2

Formula: C₇H₃ClF₆N₂O₄S₂

Purezza: 95%

Colore e forma: Solid, Chunks or Crystalline Powder

Peso molecolare: 392.67

Ref: 10-F009051

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine

Prodotto controllato

CAS: 145100-51-2

Stability Moisture Sensitive, Unstable in DMSO Solution
Applications 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine also known as Comins’ Reagent is used as a triflyl compouind in the synthesis of vinyl triflates from metallo enolates.
References Comins, D., et al.: Tetrahedron Lett., 33, 6299 (1992);

Formula: C₇H₃ClF₆N₂O₄S₂

Colore e forma: Neat

Peso molecolare: 392.68

Ref: TR-B585565