CAS 149263-94-5

6'-metil-2-piridinil-2-(acetilammino)-2-desossi-1-tio-B-D-glucopiranoside

Descrizione:

6'-metil-2-piridinil-2-(acetilammino)-2-desossi-1-tio-B-D-glucopiranoside, con il numero CAS 149263-94-5, è un composto chimico che appartiene alla classe dei glicosidi, specificamente un tio-glicoside. Questo composto presenta un anello di piridina, che contribuisce alle sue proprietà aromatiche, e un gruppo tiol che sostituisce l'ossigeno tipico nel legame glicosidico, aumentando la sua reattività e potenziale attività biologica. La presenza di un gruppo acetilamino indica che potrebbe partecipare a varie interazioni biochimiche, influenzando potenzialmente la sua solubilità e stabilità. Il gruppo metile sull'anello di piridina può influenzare le proprietà elettroniche del composto e l'ostruzione sterica, che può giocare un ruolo nella sua interazione con obiettivi biologici. In generale, le caratteristiche strutturali uniche di questo composto suggeriscono potenziali applicazioni in chimica medicinale, in particolare nello sviluppo di terapie o come sonda biochimica, sebbene specifiche attività biologiche richiederebbero ulteriori indagini.

Formula: C14H20N2O5S

InChI: InChI=1S/C14H20N2O5S/c1-7-4-3-5-10(15-7)22-14-11(16-8(2)18)13(20)12(19)9(6-17)21-14/h3-5,9,11-14,17,19-20H,6H2,1-2H3,(H,16,18)/t9-,11-,12-,13-,14+/m1/s1

InChI key: XUKXHOMZOIYNLR-FZGMBXNASA-N

SMILES: CC1=NC(=CC=C1)S[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)NC(=O)C

Sinonimi:

• Mpt-Nag
• 6-methyl-2-pyridinyl-2-(acetylamino)-2-deoxy-1-thio-β-D-glucopyranoside
• 6-Methyl-2-pyridinyl 2-(acetylamino)-2-deoxy-1-thio-beta-D-glucopyranoside

6-Methyl-2-pyridinyl 2-(acetylamino)-2-deoxy-1-thio-β-D-glucopyranoside

CAS: 149263-94-5

6-Methyl-2-pyridinyl 2-(acetylamino)-2-deoxy-1-thio-β-D-glucopyranoside

Formula: C₁₄H₂₀N₂O₅S

Purezza: ≥95%

Peso molecolare: 328.38

Ref: 54-OR1129828

6-Methyl-2-pyridinyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside

CAS: 149263-94-5

Ref: 7W-GC6100

6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside

CAS: 149263-94-5

6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside is a thioglycoside derivative featuring an N-acetyl-D-glucosamine moiety connected via a beta-thioglycosidic linkage to a 6-methyl-2-pyridyl aglycone. The thioether bond confers resistance to enzymatic hydrolysis by glycosidases while maintaining recognition by sugar-binding proteins. This thioglycoside is used as a stable substrate analog in glycosidase inhibition studies and as a probe for lectin-carbohydrate interaction mapping.

Formula: C₁₄H₂₀N₂O₅S

Peso molecolare: 328.384

Ref: TM-TXB-00173

6-Methyl-2-pyridinyl 2-(acetylamino)-2-deoxy-1-thio-β-D-glucopyranoside

CAS: 149263-94-5

Formula: C₁₄H₂₀N₂O₅S

Purezza: 95%

Peso molecolare: 328.3840

Ref: IN-DA001LIH

6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside

CAS: 149263-94-5

The 6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside is a chloride salt that has been used in the laboratory to develop an analytical method for the determination of glucose in urine samples. The bioavailability of 6MP is low and it is excreted by renal filtration, so this compound has been used as a marker for renal transplantation. Glomerular filtration rate (GFR) is reduced in diabetic patients, leading to a decrease in the amount of 6MP excreted. This drug can be administered orally or intravenously and has shown efficacy at low dose levels. Low doses have also been associated with decreased detection sensitivity due to its low level of excretion, which makes it an ideal candidate for use as a biomarker for chronic kidney disease. A chronic kidney disease animal model was used to study the effects on GFR and creatinine clearance rates

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 328.39 g/mol

Ref: 3D-EM10847