CAS 15318-45-3

tiamfenicolo

Descrizione:

tiamfenicolo è un antibiotico ad ampio spettro appartenente alla classe degli antibiotici fenicol, utilizzato principalmente per le sue proprietà antibatteriche. È efficace contro una varietà di batteri Gram-positivi e Gram-negativi, rendendolo utile nel trattamento di infezioni causate da questi microrganismi. tiamfenicolo agisce inibendo la sintesi proteica batterica, mirando specificamente alla subunità ribosomiale 50S, il che interrompe la crescita e la riproduzione dei batteri. Questo composto è spesso utilizzato in medicina veterinaria e ha applicazioni in medicina umana, in particolare nei casi in cui altri antibiotici possono essere inefficaci o controindicati. tiamfenicolo è noto per la sua capacità di penetrare nei tessuti e raggiungere concentrazioni terapeutiche, il che è vantaggioso nel trattamento di infezioni sistemiche. Tuttavia, il suo uso è associato a potenziali effetti collaterali, tra cui soppressione del midollo osseo e il rischio di anemia aplastica, portando a restrizioni in alcune regioni. La sostanza è tipicamente somministrata per via orale o tramite iniezione, e la sua farmacocinetica può variare in base alla via di somministrazione. In generale, tiamfenicolo è un antibiotico prezioso con applicazioni e considerazioni specifiche nella pratica clinica.

Formula: C₁₂H₁₅Cl₂NO₅S

InChI: InChI=1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1

InChI key: InChIKey=OTVAEFIXJLOWRX-NXEZZACHSA-N

SMILES: [C@@H]([C@H](NC(C(Cl)Cl)=O)CO)(O)C1=CC=C(S(C)(=O)=O)C=C1

Sinonimi:

• (2′R,3′R)-Thiamphenicol
• 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
• 2,2-dichloro-N-{1,3-dihydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide
• 8065Cb
• <span class="text-smallcaps">D</span>-Thiocymetin
• <span class="text-smallcaps">D</span>-Thiophenicol
• <span class="text-smallcaps">D</span>-d-threo-2-Dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol
• <span class="text-smallcaps">D</span>-threo-(1R,2R)-1-(p-Methylsulfonylphenyl)-2-dichloroacetamido-1,3-propanediol
• Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-
• Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-, [R-(R*,R*)]-
• Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]-, <span class="text-smallcaps">D</span>-threo-(+)-
• Dextrosulphenidol
• Methylsulfonyl chloramphenicol
• NSC 522822
• Thiocymetin
• Thiophenicol
• Tirsan
• Win 5063-2
• Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]-, D-threo-(+)-
• D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-P-(METHYL-SULFONYL)PHENETHYL]ACETAMIDE
• 98.0-100.5% (Assay)
• ThiocyMetin, Thiophenicol, Win 5062-2, NSC 522822
• D-d-threo-2-Dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol
• Acetamide, 2,2-dichloro-N-[b-hydroxy-a-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]-, D-threo-(+)- (8CI)
• Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]- (9CI)
• D-Thiophenicol
• D-THREO-2,2-DICHLORO-N-(BETA-HYDROXY-ALPHA-[HYDROXYMETHYL]-4-[METHYLSULFONYL]PHENETHYL)ACETAMIDE
• 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
• Acetamide, 2,2-dichloro-N-(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-4-(methylsulfonyl)phenylethyl-
• 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-hydroxymethyl-2-(4-methylsulfonylphenyl)ethyl]acetamide
• D-threo-(1R,2R)-1-(p-Methylsulfonylphenyl)-2-dichloroacetamido-1,3-propanediol
• acetamide,2,2-dichloro-n-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl
• D-threo-2,2-Dichloro-N-(b-hydroxy-a-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide
• D-Thiocymetin
• 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-[4-(methylsulfonyl)phenyl]-2-propyl]acetamide
• Thiamphenicol,D-threo-2,2-Dichloro-N-(β-hydroxy-α-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide
• d-threo-2,2-dichloro-n-(β-hydroxy-α-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide
• THIAMPHENICOL
• 8065c.b.
• 2,2-Dichloro-N[(1R,2R)-2-hydroxy-1-hydroxymethyl-2-(4-methylsulphonylphenyl)-acetamide
• ThiaMphenicol API
• ThiaMphenicol / Methylsulfonyl chloraMphenicol
• ThiamphenicolBP,
• Neomyson
• (+)-2,2-Dichloro-N-[(αR,βR)-β-hydroxy-α-(hydroxymethyl)-4-(methylsulfonyl)phenethyl]acetamide
• THIAMPHENICHOL

Thiamphenicol

CAS: 15318-45-3

Formula: C₁₂H₁₅Cl₂NO₅S

Purezza: >98.0%(HPLC)(N)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 356.21

Ref: 3B-T2802

Thiamphenicol

CAS: 15318-45-3

The methyl-sulfonyl analogue of chloramphenicol

Formula: C₁₂H₁₅Cl₂NO₅S

Colore e forma: White to yellow, Powder or crystals or crystalline powder

Peso molecolare: 356.21

Ref: 02-J63575

THIAMPHENICOL CRS

CAS: 15318-45-3

THIAMPHENICOL CRS

Formula: C₂₇H₂₉NO₁₁

Colore e forma: Added Modified

Peso molecolare: 543.5193

Ref: 41-T1100000

Thiamphenicol

CAS: 15318-45-3

Thiamphenicol

Formula: C₁₂H₁₅Cl₂NO₅S

Purezza: >98%

Peso molecolare: 356.22

Ref: 54-OR1029185

Thiamphenicol

CAS: 15318-45-3

Thiamphenicol (Dextrosulphenidol) is a methylsulfonyl analog of chloramphenicol. It is an antibiotic and immunosuppressive agent.

Formula: C₁₂H₁₅Cl₂NO₅S

Purezza: 99.08% - 99.8%

Colore e forma: White Solid

Peso molecolare: 356.22

Ref: TM-T1550

Thiamphenicol

CAS: 15318-45-3

Formula: C₁₂H₁₅Cl₂NO₅S

Purezza: 98.0 - 102.0 % (anhydrous basis)

Colore e forma: White to off-white powder

Peso molecolare: 356.22

Ref: 7W-GA2455

Thiamphenicol

CAS: 15318-45-3

Thiamphenicol

Purezza: ≥98%

Peso molecolare: 356.22g/mol

Ref: 54-BUP18635

Thiamphenicol

CAS: 15318-45-3

Formula: C₁₂H₁₅Cl₂NO₅S

Peso molecolare: 356.23

Ref: 4Z-T-612

Thiamphenicol, EP grade

CAS: 15318-45-3

Formula: C₁₂H₁₅Cl₂NO₅S

Purezza: 98.0 - 100.5 % (dried basis)

Colore e forma: White to light-yellow crystalline powder

Peso molecolare: 356.22

Ref: 7W-GA2112

Thiamphenicol

Prodotto controllato

CAS: 15318-45-3

Formula: C₁₂H₁₅Cl₂NO₅S

Colore e forma: Neat

Peso molecolare: 356.22

Ref: 04-C17457000

Thiamphenicol

Prodotto controllato

CAS: 15318-45-3

Formula: C₁₂H₁₅Cl₂NO₅S

Colore e forma: Neat

Peso molecolare: 356.22

Ref: 86-MM0737.00

Thiamphenicol 1000 µg/mL in Acetonitrile

Prodotto controllato

CAS: 15318-45-3

Formula: C₁₂H₁₅Cl₂NO₅S

Colore e forma: Single Solution

Peso molecolare: 356.22

Ref: 04-A17457000AL-1000

Thiamphenicol

Prodotto controllato

CAS: 15318-45-3

Applications Thiamphenicol is an antibiotic. Thiamphenicol is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Thiamphenicol is used particularly for the treatment of sexually transmitted infections and pelvic inflammatory disease.
References Tikhonova, E., et al.: J. Biol. Chem., 279, 32116 (2004), Baucheron, S., et al.: J. Antimicrob. Chemother., 55, 707 (2005), Pages, J., et al.: Trends. Mol. Med., 11, 382 (2005), Lomovskaya, O., et al.: Biochem. Pharmacol., 71, 910 (2006), Samosorn, S., et al.: Bioorg. Med. Chem., 14, 857 (2006),

Formula: C₁₂H₁₅Cl₂NO₅S

Colore e forma: Neat

Peso molecolare: 356.22

Ref: TR-T344160

Thiamphenicol-methyl-d3

Prodotto controllato

CAS: 15318-45-3

Applications Labelled Thiamphenicol (T344160). Thiamphenicol is an antibiotic. Thiamphenicol is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Thiamphenicol is used particularly for the treatment of sexually transmitted infections and pelvic inflammatory disease.
References Tikhonova, E., et al.: J. Biol. Chem., 279, 32116 (2004), Baucheron, S., et al.: J. Antimicrob. Chemother., 55, 707 (2005), Pages, J., et al.: Trends. Mol. Med., 11, 382 (2005), Lomovskaya, O., et al.: Biochem. Pharmacol., 71, 910 (2006), Samosorn, S., et al.: Bioorg. Med. Chem., 14, 857 (2006),

Formula: C₁₂H₁₂D₃Cl₂NO₅S

Colore e forma: Neat

Peso molecolare: 359.23

Ref: TR-T344163

Thiamphenicol (THP), 98%

CAS: 15318-45-3

Formula: C₁₂H₁₅Cl₂NO₅S

Purezza: min. 98%

Colore e forma: White to off white, Crystalline powder

Peso molecolare: 356.22

Ref: SR-79903

Thiamphenicol

CAS: 15318-45-3

Formula: C₁₂H₁₅Cl₂NO₅S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 356.21

Ref: 10-F510285

Thiamphenicol

CAS: 15318-45-3

Thiamphenicol is a semisynthetic derivative of chloramphenicol with action on bacterial protein synthesis inhibition and is used for treating bacterial infections, particularly in veterinary medicine.

Formula: C₁₂H₁₅Cl₂NO₅S

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 356.22 g/mol

Ref: 3D-AT38721

Thiamphenicol

CAS: 15318-45-3

Formula: C₁₂H₁₅Cl₂NO₅S

Peso molecolare: 356.21

Ref: ST-EA-CP-T147000

2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide

CAS: 15318-45-3

Formula: C₁₂H₁₅Cl₂NO₅S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 356.2222

Ref: IN-DA00HY3Z