CAS 15663-27-1

Cisplatino

Descrizione:

Cisplatino, con il numero CAS 15663-27-1, è un farmaco chemioterapico a base di platino ampiamente utilizzato nel trattamento di vari tumori, tra cui il cancro testicolare, ovarico, della vescica e polmonare. La sua formula chimica è cis-[Pt(NH3)2Cl2], il che indica che è composto da un atomo di platino coordinato a due molecole di ammoniaca e due ioni cloruro. Il composto è caratterizzato dalla sua geometria quadrata planare, che è cruciale per la sua attività biologica. Cisplatino funziona principalmente formando legami incrociati nel DNA, inibendo così la replicazione e la trascrizione del DNA, portando all'apoptosi nelle cellule tumorali a rapida divisione. Viene tipicamente somministrato per via endovenosa e può avere effetti collaterali come nefrotossicità, nausea e mielosoppressione. L'efficacia del farmaco può essere influenzata da fattori come la presenza di specifiche proteine cellulari e il microambiente tumorale. A causa del suo meccanismo d'azione, Cisplatino è spesso utilizzato in combinazione con altri agenti chemioterapici per migliorare l'efficacia terapeutica e superare la resistenza.

Formula: Cl₂H₆N₂Pt

InChI: InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2

InChI key: InChIKey=LXZZYRPGZAFOLE-UHFFFAOYSA-L

SMILES: [Pt+2]([Cl-])([Cl-])([NH3])[NH3]

Sinonimi:

• (SP-4-2)-Diamminedichloroplatinum
• Abiplatin
• Biocisplatinum
• Briplatin
• CP Ethypharm
• Cacp
• Cddp
• Cis-Platinum(Ii)Diammine Dichloride
• Cismaplat
• Cisplatin
• Cisplatine
• Cisplatine Mylan
• Cisplatino
• Cisplatinum
• Cisplatyl
• Citoplatino
• Citoplax
• Cpdc
• Cpdd
• Cppd
• DDP
• DDP (antitumor agent)
• DichlorodiammineplatinumIIyelloworangextl
• Fauldiscipla
• IA-call
• Kemoplat
• Lederplatin
• LiPlaCis
• Lipoplatin
• Maruko
• Neoplatin
• Nsc 119875
• Platamine
• Platiblastin
• Platidiam
• Platinex
• Platinol
• Platinol AQ
• Platinoxan
• Platinum, diamminedichloro-, (SP-4-2)-
• Platinum, diamminedichloro-, cis-
• Platinumdiamminechloride
• Platistin
• Platosin
• Rand
• Randa
• SPI 077 (complex)
• Spi 077
• Spi 077B103
• Tr 170
• cis-DDP
• cis-Diaminedichloridoplatinum(II)
• cis-Diaminedichloroplatinum
• cis-Diaminedichloroplatinum(II)
• cis-Diaminodichloroplatinum(II)
• cis-Diamminedichloroplatinum
• cis-Diamminedichloroplatinum(II)
• cis-Diammineplatinum(II)
• cis-Diammineplatinum(II) dichloride
• cis-Dichlorodiammineplatinum
• cis-Dichlorodiammineplatinum(II)
• cis-Platin
• cis-Platine
• cis-Platinous diaminodichloride
• cis-Platinum
• cis-Platinum II
• cis-Platinum diaminodichloride
• cis-Platinum(II) diaminodichloride
• cis-Platinum(II) diammine chloride
• cis-Platinum(II) diamminedichloride
• cis-Platinumdiamine dichloride
• cis-Platinumdiammine dichloride

cis-Diammineplatinum(II) Dichloride

CAS: 15663-27-1

Formula: H₆Cl₂N₂Pt

Colore e forma: Light orange to Yellow to Green powder to crystal

Peso molecolare: 300.05

Ref: 3B-D3371

cis-Diamminedichloroplatinum(II), Pt 64.5% min

CAS: 15663-27-1

Being a potent anticancer agent that blocks DNA synthesis, the pharmaceutical compositions are used in chemotherapy. First member of platinum-containing anti-cancer drugs. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and

Formula: Cl₂H₆N₂Pt

Purezza: 64.5%

Peso molecolare: 300.04

Ref: 02-010471

cis-Dichlorodiammine platinum(II), 99% CISPLATIN

CAS: 15663-27-1

cis-Dichlorodiammine platinum(II), 99% CISPLATIN

Formula: cisPt(NH₃)₂Cl₂

Purezza: 99%

Colore e forma: yellow to orange xtl.

Peso molecolare: 300.06

Ref: 08-78-0450

CISPLATIN RS

CAS: 15663-27-1

CISPLATIN RS

Formula: H₄Cl₂N₂Pt

Colore e forma: Powder

Peso molecolare: 298.0352

Ref: 41-ICRS0258

Cisplatin

CAS: 15663-27-1

Cisplatin

Formula: Cl₂H₆N₂Pt

Purezza: 100.0%

Colore e forma: Yellow

Peso molecolare: 298.9556

Ref: 47-809

CISPLATIN CRS

CAS: 15663-27-1

CISPLATIN CRS

Formula: H₄Cl₂N₂Pt

Colore e forma: Powder

Peso molecolare: 298.0352

Ref: 41-C2210000

Cisplatin

CAS: 15663-27-1

Inorganic or organic compounds of precious metals, whether or not chemically defined; amalgrams of precious metals, nesoi

Formula: Cl₂H₆N₂Pt

Colore e forma: Yellow Orange Powder

Peso molecolare: 298.9556

Ref: 45-1134357

Cisplatin

CAS: 15663-27-1

Cisplatin

Formula: Cl₂H₆N₂Pt

Purezza: ≥95%

Colore e forma: Solid

Peso molecolare: 300.04

Ref: 54-BUP15896

Cisplatin

CAS: 15663-27-1

Cisplatin (CDDP) is a DNA cross-linking agent.

Formula: Cl₂H₆N₂Pt

Purezza: 97.13% - 99.63%

Colore e forma: Solid

Peso molecolare: 300.04

Ref: TM-T1564

dichloroplatinum diamine

CAS: 15663-27-1

Formula: Cl₂H₆N₂Pt

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 300.0450

Ref: IN-DA0034MA

Cisplatin, USP grade

CAS: 15663-27-1

Formula: Cl₂H₆N₂Pt

Purezza: ≥ 4.5

Colore e forma: Yellow to orange powder

Peso molecolare: 300.06

Ref: 7W-GP5927

Cisplatin

CAS: 15663-27-1

Formula: Cl₂H₆N₂Pt

Colore e forma: Yellow Solid

Peso molecolare: 300.05

Ref: 4Z-C-236001

Cisplatin

CAS: 15663-27-1

Formula: Cl₂H₆N₂Pt

Purezza: ≥ 98.0% (anhydrous)

Colore e forma: Yellow to orange powder

Peso molecolare: 300.06

Ref: 7W-GA8978

Cisplatin

CAS: 15663-27-1

cis-Diaminodichloroplatinum(II)

Formula: Cl₂H₆N₂Pt

Purezza: 99%

Peso molecolare: 300.05

Ref: IN-DG121788

cis-Dichlorodiamine platinum(II); 99.95% (metals basis)

CAS: 15663-27-1

Formula: Pt(NH₃)₂Cl₂

Purezza: ≥ 99.95%

Colore e forma: Yellow to orange powder or crystals

Peso molecolare: 300.06

Ref: 7W-GX4154

Cisplatin RS

CAS: 15663-27-1

Colore e forma: Yellow Solid Crystalline Powder

Ref: 2K-106600002

Cisplatin

Prodotto controllato

CAS: 15663-27-1

Formula: Cl₂H₆N₂Pt

Colore e forma: Neat

Peso molecolare: 300.04

Ref: TR-C499500

Cisplatin - Bio-X ™

CAS: 15663-27-1

Cisplatin, also known as cisplatinum, is a platinum-based anti-cancer agent that inhibits the EGFR, which is a receptor tyrosine kinase. It has been shown to have anti-cancer effects in melanoma cells and to inhibit tumor growth in mice. Cisplatin acts by interfering with the mechanism of DNA repairing. It loses one chloride ligand and binds to DNA to inhibit the synthesis, causing DNA damage, and thus inducing apoptosis in cancer cells. In certain studies, the use of cisplatin in combination with other metal chelators has shown improvement in the uptake of the anticancer drug. CisplatiN - Bio-X™ is part of our Bio-X™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: Cl₂H₆N₂Pt

Purezza: Min. 99%

Colore e forma: Powder

Peso molecolare: 300.05 g/mol

Ref: 3D-BC164315

Cisplatin

CAS: 15663-27-1

Cisplatin is a chemotherapeutic drug that inhibits the growth of cancer cells by binding to DNA. It binds to DNA and inhibits transcription and replication, leading to the accumulation of p-glycoprotein (P-gp) inhibitor in the cell membrane, which prevents the efflux of intracellular caspase activators. This leads to an increase in apoptosis among cancer cells and a decrease in healthy tissue. The toxicology of cisplatin has been studied extensively, with low-dose groups showing no signs of toxicity.

Formula: Cl₂H₆N₂Pt

Purezza: (Hplc) 98 To 102%

Colore e forma: Yellow Powder

Peso molecolare: 300.05 g/mol

Ref: 3D-FC20460

Cisplatin

CAS: 15663-27-1

Purezza: 98%

Peso molecolare: 298.96

Ref: 10-F554436