
CAS 1567915-38-1
:Formula:C26H30N6O3
InChI:InChI=1S/C26H30N6O3/c1-16-13-34-11-10-31(16)26-29-23-21(24(30-26)32-19-6-7-20(32)15-35-14-19)8-9-22(28-23)17-4-3-5-18(12-17)25(33)27-2/h3-5,8-9,12,16,19-20H,6-7,10-11,13-15H2,1-2H3,(H,27,33)/t16-,19?,20?/m0/s1
InChI key:LVPBYQVQBZLDAU-DZIBYMRMSA-N
SMILES:C[C@H]1COCCN1C2=NC3=C(C=CC(=N3)C4=CC(=CC=C4)C(=O)NC)C(=N2)N5C6CCC5COC6
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MTI-31
CAS:MTI-31 is a synthetic, orally bioavailable small molecule that binds to the regulatory domain of the GRP78 protein. MTI-31 has been shown to have antiproliferative effects in vitro and in vivo by inhibiting the activity of the protein synthesis machinery. It also suppresses tumor growth and induces an antitumor response. MTI-31 interacts with pd-l1, a receptor for phosphatidylserine, which has been implicated in cancer cell proliferation and apoptosis. The kinase domain of MTI-31 inhibits tumor growth by preventing cellular proliferation and inducing apoptosis.Formula:C26H30N6O3Purezza:Min. 95%Peso molecolare:474.6 g/molMTI-31
CAS:MTI-31 (LXI-15029) is a potent oral mTORC1/2 inhibitor with a Kd of 0.20 nM, >5,000-fold selectivity, and an IC50 of 39 nM.Formula:C26H30N6O3Purezza:99.97%Colore e forma:Yellow SolidPeso molecolare:474.5548




