
CAS 1617495-03-0
:Formula:C28H23Cl5N2O2
InChI:InChI=1S/C28H22Cl4N2O2.ClH/c29-22-8-6-18(12-24(22)31)10-20-15-34(28(36)26(33)14-17-4-2-1-3-5-17)16-21(27(20)35)11-19-7-9-23(30)25(32)13-19;/h1-13,26H,14-16,33H2;1H/b20-10-,21-11-;/t26-;/m0./s1
InChI key:UMWXLEVUBFNYIK-VCCJZKHWSA-N
SMILES:C\1N(C/C(=C/C2=CC(=C(C=C2)Cl)Cl)/C(=O)/C1=C\C3=CC(=C(C=C3)Cl)Cl)C(=O)[C@@H](N)CC4=CC=CC=C4.Cl
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1-(L-Phenylalanyl)-3,5-Bis(3,4-Dichlorobenzylidene)Piperidin-4-One Hydrochloride
CAS:1-(L-Phenylalanyl)-3,5-Bis(3,4-Dichlorobenzylidene)Piperidin-4-One HydrochlorideFormula:C28H23Cl5N2O2Purezza:98%Peso molecolare:596.76RA190
CAS:RA190 inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.Formula:C28H23Cl5N2O2Purezza:97.7%Colore e forma:SolidPeso molecolare:596.76Ref: TM-T13858
1mg54,00€5mg109,00€1mL*10mM (DMSO)142,00€10mg159,00€25mg233,00€50mg414,00€100mg608,00€1-(L-phenylalanyl)-3,5-bis(3,4-dichlorobenzylidene)piperidin-4-one hydrochloride
CAS:Formula:C28H23Cl5N2O2Purezza:98%Peso molecolare:596.7594RA190
CAS:1-(L-phenylalanyl)-3,5-bis(3,4-dichlorobenzylidene)piperidin-4-one hydrochlorideFormula:C28H23Cl5N2O2Purezza:98%Peso molecolare:596.76RA190
CAS:RA190 is a small molecule inhibitor of the ubiquitin ligase RNF4. It inhibits the proteasome, which is responsible for protein degradation, by targeting the ubiquitin ligases that mediate ubiquitination and subsequent degradation of proteins. This inhibition leads to accumulation of cellular proteins and cell death. RA190 has been shown effective in killing cancer cells in vitro and in vivo. Furthermore, RA190 can inhibit autoimmune diseases by modulating the immune system's response to self-antigens.
Formula:C28H23Cl5N2O2Purezza:Min. 95%Peso molecolare:596.76 g/mol




