
CAS 1642303-38-5
:Formula:C29H29FN7O5P
InChI:InChI=1S/C29H26FN7O.H3O4P/c1-35-28(38)25-26(31-20-7-3-2-4-8-20)36(34-27(25)37-23-11-5-10-22(23)33-29(35)37)17-18-13-15-19(16-14-18)21-9-6-12-24(30)32-21;1-5(2,3)4/h2-4,6-9,12-16,22-23,31H,5,10-11,17H2,1H3;(H3,1,2,3,4)/t22-,23+;/m1./s1
InChI key:ZPIAAFIYOPWWJL-RFPXDPOKSA-N
SMILES:CN1C(=O)C2=C(N(N=C2N3C1=N[C@H]4[C@@H]3CCC4)CC5=CC=C(C=C5)C6=NC(=CC=C6)F)NC7=CC=CC=C7.OP(=O)(O)O
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ITI-214
CAS:ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members, exhibits potent PDE1 inhibitory activity.Formula:C29H29FN7O5PPurezza:98.21% - 98.81%Colore e forma:SolidPeso molecolare:605.56ITI-214
CAS:(6AR,9aS)-2-(4-(6-fluoropyridin-2-yl)benzyl)-5-methyl-3-(phenylamino)-5,6a,7,8,9,9a-hexahydrocyclopenta[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2H)-one phosphateFormula:C29H29FN7O5PPurezza:98+%Peso molecolare:605.56ITI-214 phosphate
CAS:Prodotto controllatoITI-214 is a novel non-steroidal anti-inflammatory drug (NSAID) that has been shown to have potent anti-inflammatory and analgesic effects in animal models. ITI-214 targets phosphodiesterases, which are enzymes that break down the signaling molecule cyclic AMP. This leads to an increase in cyclic AMP levels, which can then activate protein kinase A and inhibit the production of pro-inflammatory cytokines. The safety profile of ITI-214 has been evaluated in clinical studies involving humans with osteoarthritis and rheumatoid arthritis. The drug was well tolerated and did not produce any serious adverse events. ITI-214 also has other physiological functions, including the enhancement of locomotor activity and blood pressure control.Formula:C29H29FN7O5PPurezza:Min. 95%Peso molecolare:605.56 g/mol




