CAS 1654725-02-6
:Formula:C16H20N4O3S
InChI:InChI=1S/C16H20N4O3S/c1-15(2)7-8-10(12(17)21)14(24-11(8)16(3,4)23-15)19-13(22)9-5-6-18-20-9/h5-6H,7H2,1-4H3,(H2,17,21)(H,18,20)(H,19,22)
InChI key:GHTGYZMBQPXTCQ-UHFFFAOYSA-N
SMILES:CC1(CC2=C(C(O1)(C)C)SC(=C2C(=O)N)NC(=O)C3=CC=NN3)C
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N-(3-Carbamoyl-5,5,7,7-Tetramethyl-5,7-Dihydro-4H-Thieno[2,3-c]Pyran-2-Yl)-1H-Pyrazole-3-Carboxamide
CAS:N-(3-Carbamoyl-5,5,7,7-Tetramethyl-5,7-Dihydro-4H-Thieno[2,3-c]Pyran-2-Yl)-1H-Pyrazole-3-CarboxamideFormula:C16H20N4O3SPurezza:99%Peso molecolare:348.42GLPG1837
CAS:GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.Formula:C16H20N4O3SPurezza:99.64% - 99.91%Colore e forma:SolidPeso molecolare:348.42N-(3-Carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-3-carboxamide
CAS:N-(3-Carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-3-carboxamideFormula:C16H20N4O3SPurezza:99%Peso molecolare:348.42N-[3-(Aminocarbonyl)-4,7-dihydro-5,5,7,7-tetramethyl-5H-thieno[2,3-c]pyran-2-yl]-1H-pyrazole-3-carboxamide
CAS:Formula:C16H20N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:348.4200GLPG 1837
CAS:GLPG 1837 is a small molecule potentiator, which is derived from a synthetic compound designed to target cystic fibrosis transmembrane conductance regulator (CFTR) protein variants. The source of GLPG 1837 is based on medicinal chemistry approaches focused on optimizing interactions with CFTR. The mode of action involves enhancing the channel gating of the CFTR protein, specifically addressing defects in CFTR function by increasing the probability of the channel being open and facilitating chloride ion transport across cell membranes.Formula:C16H20N4O3SPurezza:Min. 95%Peso molecolare:348.42 g/mol
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