CAS 16679-58-6

Desmopressina

Descrizione:

Desmopressina è un analogo sintetico della vasopressina, un ormone che si verifica naturalmente e che regola la ritenzione di acqua nel corpo. È utilizzato principalmente nel trattamento di condizioni come il diabete insipido e l'enuresi notturna. Desmopressina mostra un'alta affinità per i recettori V2 della vasopressina, che si trovano principalmente nei reni, portando a un aumento del riassorbimento dell'acqua e a una riduzione della produzione di urina. La sostanza è caratterizzata dalla sua capacità di aumentare la concentrazione dell'urina senza influenzare significativamente la pressione sanguigna, rendendola una scelta preferita per i pazienti con esigenze mediche specifiche. Desmopressina è tipicamente somministrato in varie forme, tra cui spray nasale, compresse orali e soluzioni iniettabili. La sua farmacocinetica indica una vita media relativamente lunga rispetto alla vasopressina naturale, consentendo una somministrazione meno frequente. Inoltre, Desmopressina è generalmente ben tollerato, sebbene gli effetti collaterali potenziali possano includere mal di testa, nausea e, in rari casi, ritenzione idrica che può portare a iponatremia. In generale, Desmopressina è un agente terapeutico prezioso nella gestione di alcuni disturbi legati all'equilibrio idrico nel corpo.

Formula: C₄₆H₆₄N₁₄O₁₂S₂

InChI: InChI=1/C46H64N14O12S2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52)/t28-,29+,30+,31+,32+,33+,34+/m1/s1

InChI key: NFLWUMRGJYTJIN-PNIOQBSNSA-N

SMILES: C1C[C@H](N(C1)C(=O)[C@@H]2CSSCCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)C(=O)N[C@H](CCCN=C(N)N)C(=O)NCC(=O)N

Sinonimi:

• 1-(3-Mercaptopropanoic acid)-8-D-argininevasopressin
• 1-{[(4R,7S,10S,13S,16S)-7-(2-Amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-arginylglycinamide
• 16679-58-6
• 240-726-7
• glycinamide, 1-[[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-4-yl]carbonyl]-L-prolyl-L-arginyl-
• Octostim
• 1-{[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-N~5~-(diaminomethylidene)-D-ornithylglycinamide
• (1-Deamino-8-D-Arg)-vasopressin
• [1-β-Mercaptopropionic acid-8-D-arginine]vasopressin
• [Deamino1-D-arginine8]vasopressin
• [Desamino-Cys1,D-Arg8]vasopressin
• 1-(3-Mercaptopropionic acid)-8-D-arginine-vasopressin
• 1: PN: US20020013262 PAGE: 2 claimed protein
• 1-Deamino-[8-D-arginine]vasopressin
• 1-Deamino-1-[D-Arg8]-vasopressin
• 1-Desamino-8-D-arginine-vasopressin
• 1-Desaminocystine-8-D-arginine-vasopressin
• 45: PN: WO2005000360 SEQID: 40 claimed protein
• 8-D-Arginine deaminovasopressin
• Adiuretin
• Adiuretin SD
• DAV Ritter
• Ddavp
• Desmopresina
• Desmopressine
• Desmospray
• Glycinamide, N-(3-mercapto-1-oxopropyl)-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-D-arginyl-, cyclic (1→5)-disulfide
• Minirin
• Minrin
• Peptide, (Xaa-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly), ?
• Vasopressin, 1-(3-mercaptopropanoic acid)-8-D-arginine-
• Vasopressin, 1-(3-mercaptopropionic acid)-8-D-arginine-
• (Deamino-Cys1,D-Arg8)-Vasopressin acetate salt
• 3-Mercaptopropionyl-Tyr-Phe-Gln-Asn-Cys-Pro-D-Arg-Gly-NH2 acetate salt (Disulfide bond)
• [DEAMINO1, DARG8] VASOPRESSIN
• [deamino-cys1, d-arg8]-vasopressin acetate hydrate
• [deamino-Cys
• DESMOPRESSIN, HUMAN
• MPR-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2
• [Deamino1,DArg8] Vasopressin (dDAVP) Desmopressin
• 3-MERCAPTOPROPIONYL-YFQNCPRG (DISULFIDE BRIDGE: 1-6)
• DESMOPRESSIN
• M.W. 1069.22 C46H64N14O12S2
• MAP-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2
• 3-Mercapto(1)propionyl-L-Tyr-L-Phe-L-Gln-L-Asn-L-Cys(1)-L-Pro-D-Arg-Gly-NH2
• 3-MERCAPTOPROPIONYL-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2
• DDAVP, HUMAN
• DESMOPRESSIN ACETATE PH. EUR.
• DESAMINO-[D-ARG8]VASOPRESSIN
• [DEAMINO-CYS1, D-ARG8]-VASOPRESSIN

(Deamino-Cys¹,D-Arg⁸)-Vasopressin

CAS: 16679-58-6

Desmopressin (DDAVP), as the first vasopressin analog with a very high and very specific antidiuretic effect, has been widely used for different therapeutic purposes. DDAVP also improves human learning and memory processes. CAS Number (desmopressin acetate): 62288-83-9.

Formula: C₄₆H₆₄N₁₄O₁₂S₂

Purezza: 99.7%

Colore e forma: White Powder

Peso molecolare: 1069.23

Ref: 01-4012273

Desmopressin impurity standard

CAS: 16679-58-6

Desmopressin impurity standard

Colore e forma: Off-White

Ref: 47-1188

Desmopressin

CAS: 16679-58-6

Desmopressin

Formula: C₄₆H₆₄N₁₄O₁₂S₂

Colore e forma: Off White Solid

Peso molecolare: 1068.42696

Ref: 47-381

Desmopressin

CAS: 16679-58-6

Desmopressin (DDAVP)(DDAVP) is the synthetic analogue of the antidiuretic hormone arginine vasopressin.Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis, nocturia, and diabetes insipidus. Desmopressin works by limiting the amount of water that is eliminated in the urine. Desmopressin binds to V2 receptors in renal collecting ducts, increasing water reabsorption. It also stimulates release of von Willebrand factor from endothelial cells by acting on the V2 receptor.

Formula: C₄₆H₆₄N₁₄O₁₂S₂

Purezza: 97.45%

Peso molecolare: 1069.217

Ref: TM-T5019

Desmopressin

CAS: 16679-58-6

Formula: C₄₆H₆₄N₁₄O₁₂S₂

Colore e forma: White To Off-White Solid

Peso molecolare: 1069.22

Ref: 4Z-PD-821

Desmopressin Trifluoroacetate

CAS: 16679-58-6

Formula: C₄₆H₆₄N₁₄O₁₂S₂·C₂HF₃O₂

Colore e forma: Off-White Solid

Peso molecolare: 1069.24 114.02

Ref: 4Z-PD-8212

Desmopressin Acetate

CAS: 16679-58-6

Formula: C₄₆H₆₄N₁₄O₁₂S₂

Purezza: 95%~99%

Colore e forma: White to Off-white Powder

Peso molecolare: 1069.22

Ref: BP-BPPG021

(D-Asn)-Desmopressin

Prodotto controllato

CAS: 16679-58-6

Formula: C₄₆H₆₄N₁₄O₁₂S₂·x(C₂H₄O₂)

Colore e forma: Neat

Peso molecolare: 1069.2

Ref: TR-A788858

Asp(5)-Desmopressin Acetate Salt

Prodotto controllato

CAS: 16679-58-6

Formula: C₄₈H₆₈N₁₄O₁₄S₂

Colore e forma: Neat

Peso molecolare: 1129.27

Ref: TR-A788625

Desmopressin-[d5]

CAS: 16679-58-6

Formula: C₄₆H₆₄N₁₄O₁₂S₂

Peso molecolare: 1069.2

Ref: BE-MD-7637

Desmopressin

CAS: 16679-58-6

Formula: C₄₆H₆₄N₁₄O₁₂S₂

Peso molecolare: 1069.22

Ref: ST-EA-CP-D239000

Desmopressin

Prodotto controllato

CAS: 16679-58-6

Desmopressin is a synthetic analog of the natural hormone arginine vasopressin. It has been shown to be effective in the treatment of primary nocturnal enuresis, and a number of studies have reported that desmopressin is an effective therapy for idiopathic nocturnal enuresis. Desmopressin also has effects on water permeability, hemolysis, and protein synthesis. It increases the concentration of camp levels in urine and plasma while also inhibiting erythrocyte aggregation. Desmopressin has been shown to be more effective than placebo in women with primary nocturnal enuresis.

Formula: C₄₆H₆₄N₁₄O₁₂S₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 1,069.22 g/mol

Ref: 3D-FD110210