CAS 167466-66-2

Formula: C5H8O3S

InChI: InChI=1S/C5H8O3S/c1-3(5(7)8)9-4(2)6/h3H,1-2H3,(H,7,8)/t3-/m0/s1

InChI key: SQFDPVZBYCOAJO-VKHMYHEASA-N

SMILES: C[C@@H](C(=O)O)SC(=O)C

(S)-2-(Acetylthio)-propanoic Acid

Prodotto controllato

CAS: 167466-66-2

Applications (S)-2-(Acetylthio)-propanoic Acid is an intermediate in synthesizing (R)-(+)-Thiolactomycin (T350880). It is a natural product inhibitor of β-Ketoacyl-AcpM Synthase A (KasA). It inhibits the synthesis of mycolic acid which is a major cell wall component of Mycobacterium tuberculosis. Also an inhibitor of D-Aspartate oxidase (DDO).
References Kapilashrami, K., et al.: J. Biol. Chem., 288, 6045 (2013); Paneerselvam, V., et al.: J. Pharm. Res., 4, 4618 (2011); Katane, M., et al.: Biochimie, 92, 1371 (2010)

Formula: C₅H₈O₃S

Colore e forma: Neat

Peso molecolare: 148.18

Ref: TR-A189223