CAS 16937-99-8

tert-Butilossicarbonil-D-leucina

Descrizione:

tert-Butilossicarbonil-D-leucina, comunemente abbreviato come Boc-D-leucina, è un derivato dell'aminoacido leucina, caratterizzato dalla presenza di un gruppo protettivo tert-butilossicarbonilico (Boc). Questo composto è tipicamente utilizzato nella sintesi di peptidi come gruppo protettivo per la funzionalità amminica, che aiuta a prevenire reazioni indesiderate durante il processo di sintesi. Il gruppo Boc è noto per la sua stabilità in condizioni basiche e può essere facilmente rimosso in condizioni acide, rendendolo una scelta popolare nella sintesi organica. tert-Butilossicarbonil-D-leucina è un solido bianco a bianco sporco, e la sua struttura molecolare include una catena laterale alifatica ramificata, caratteristica della leucina, che contribuisce alle sue proprietà idrofobiche. Il composto è solubile in solventi organici come il diclorometano e il dimetilformammide, ma ha una solubilità limitata in acqua. Le sue applicazioni si estendono oltre la sintesi di peptidi per includere studi in biochimica e chimica medicinale, dove funge da blocco di costruzione per vari composti bioattivi.

Formula: C₁₁H₂₁NO₄

InChI: InChI=1S/C11H21NO4/c1-7(2)6-8(9(13)14)12-10(15)16-11(3,4)5/h7-8H,6H2,1-5H3,(H,12,15)(H,13,14)/t8-/m1/s1

InChI key: InChIKey=MDXGYYOJGPFFJL-MRVPVSSYSA-N

SMILES: [C@@H](NC(OC(C)(C)C)=O)(CC(C)C)C(O)=O

Sinonimi:

• (2R)-2-[[(tert-Butoxy)carbonyl]amino]-4-methylpentanoic acid
• (2R)-4-Methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid
• (R)-2-(tert-Butoxycarbonylamino)-4-methylpentanoic acid
• (R)-2-[[tert-Butoxycarbonyl)amino]-4-methylpentanoicacid
• (R)-N-(t-Butoxycarbonyl)leucine
• <span class="text-smallcaps">D</span>-Boc leucine
• <span class="text-smallcaps">D</span>-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-
• Boc-D-Leu-OH hydrate
• Boc-D-Leu-OH.H2O
• Boc-D-Leu-Oh
• Boc-D-Leucine
• L-Leucine-5,5,5-D3, N-T-Boc Deriv.H20
• Leucine, N-carboxy-, N-tert-butyl ester, <span class="text-smallcaps">D</span>-
• N-(Tert-Butoxycarbonyl)-D-Leucine
• N-(tert-Butoxycarbonyl)-<span class="text-smallcaps">D</span>-leucine
• N-(tert-butoxycarbonyl)-D-leucine hydrate
• N-Alpha-T-Boc-D-Leucine
• N-Boc-<span class="text-smallcaps">D</span>-leucine
• N-Boc-D-Leu-OH monohydrate
• N-T-Boc-D-Leucine
• N-Tert-Butoxycarbonyl-D-Leucine 1-Hydrate
• N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">D</span>-leucine
• tert-Butoxycarbonyl-<span class="text-smallcaps">D</span>-leucine
• Leucine, N-carboxy-, N-tert-butyl ester, D-
• N-[(1,1-Dimethylethoxy)carbonyl]-D-leucine
• D-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-

N-Boc-D-leucine hydrate, 98+%

CAS: 16937-99-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₁H₂₃NO₅

Purezza: 98+%

Colore e forma: Crystals or powder or crystalline powder, White

Peso molecolare: 249.31

Ref: 02-L09124

Boc-D-Leu-OH · H₂O

CAS: 16937-99-8

Bachem ID: 4002976.

Formula: C₁₁H₂₁NO₄·H₂O

Purezza: > 99%

Colore e forma: White

Peso molecolare: 249.31

Ref: 01-4002976

Boc-D-Leu-OH

CAS: 16937-99-8

Formula: C₁₁H₂₁NO₄xH₂O

Peso molecolare: 231.29

Ref: 7W-GM6632

Boc-D-leucine

CAS: 16937-99-8

Boc-D-leucine

Formula: C₁₁H₂₁NO₄

Purezza: >98%

Peso molecolare: 231.28874

Ref: 54-OR452082

BOC-D-Leucine monohydrate

CAS: 16937-99-8

Formula: C₁₁H₂₃NO₅

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 249.3040

Ref: IN-DA00IKJ0

N-Boc-D-leucine

Prodotto controllato

CAS: 16937-99-8

Applications N-Boc-D-leucine is an N-Boc-protected form of D-Leucine (L330150). D-Leucine is an unnatural isomer of L-Leucine (L330110) that acts as an auto-inhibitor of lactic streptococci in culture. D-Leucine causes analgesia in humans and also exhibits inhibitory activity in bacterial cell cultures.
References Chuan, Y., et al.: Chin. J. Anim. Vet. Sci., 4, 003 (1985); Fox, S., et al.: J. Biol. Chem., 155, 465 (1944); Gillillad, S. & Speck, M.: J. Dairy Sci., 51, 1573 (1968); Schoenheimer, R., et al.: J. Biol. Chem., 130, 703 (1939); Seltzer, S., et al.: Pain, 11, 141 (1981)

Formula: C₁₁H₂₁NO₄

Colore e forma: Neat

Peso molecolare: 231.29

Ref: TR-B656800

Boc-D-Leu-OH

CAS: 16937-99-8

Boc-D-Leu-OH

Formula: C₁₁H₂₁NO₄

Purezza: 95%

Peso molecolare: 231.29

Ref: IN-DG294155

Boc-D-Leu-OH • H2O

CAS: 16937-99-8

Boc-D-Leu-OH • H2O is an intramolecular hydrogen. It has a helical structure and forms hydrogen bonds with other molecules. Boc-D-Leu-OH • H2O is a cyclic peptide with a hydrophobic side chain and a hydrophilic head group. The peptide has been shown to have antimicrobial activity in the biliary and intestinal tract, as well as chronic pain relief properties. Boc-D-Leu-OH • H2O was found to be effective in animal studies for neuropathic pain, which may be due to its amide structure. A silico analysis revealed that the drug substance had a high binding affinity for the mu opioid receptor and could potentially be used to treat chronic pain caused by inflammation.

Formula: C₁₁H₂₁NO₄•H₂O

Purezza: Min. 95%

Peso molecolare: 249.31 g/mol

Ref: 3D-BDL-2603

Boc-D-Leu-OH

CAS: 16937-99-8

M03296 - Boc-D-Leu-OH

Formula: C₁₁H₂₁NO₄

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 231.292

Ref: 10-M03296

BOC-D-Leucine extrapure, 98%

CAS: 16937-99-8

Formula: C₁₁H₂₁NO₄

Purezza: min. 98%

Colore e forma: White, Crystalline powder

Peso molecolare: 231.30

Ref: SR-22237

Boc-D-Leu-OH

CAS: 16937-99-8

Boc-D-Leu-OH is a cyclic peptide that has been shown to have antibacterial activity. It is a monomer with a hydroxy group and a cavity. Boc-D-Leu-OH was found to be able to transport hydrophobic compounds across membranes, which may be due to its hydrophobic nature. Boc-D-Leu-OH also induces apoptosis in cells, which can lead to cancer. This compound has been optimized by structural modifications and residue substitutions, which have led to improved properties such as enhanced stability and increased antimicrobial activity.

Formula: C₁₁H₂₁NO₄

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 231.29 g/mol

Ref: 3D-RAA93799