CAS 169590-42-5
:Celecoxib
Descrizione:
Celecoxib è un farmaco antinfiammatorio non steroideo (FANS) utilizzato principalmente per il trattamento del dolore e dell'infiammazione associati a condizioni come l'artrite. Inibisce selettivamente l'enzima cicloossigenasi-2 (COX-2), che gioca un ruolo chiave nel processo infiammatorio, riducendo così la produzione di prostaglandine che mediano il dolore e l'infiammazione. Celecoxib è caratterizzato dalla sua formula chimica C17H14F3N3O2S e da un peso molecolare di circa 381,37 g/mol. Viene tipicamente somministrato per via orale ed è noto per i suoi effetti collaterali gastrointestinali relativamente inferiori rispetto ai FANS tradizionali, poiché risparmia l'enzima COX-1, coinvolto nella protezione della mucosa gastrica. Celecoxib è anche riconosciuto per i suoi potenziali rischi cardiovascolari, in particolare nell'uso a lungo termine, richiedendo una selezione e un monitoraggio attenti dei pazienti. La sostanza è generalmente ben assorbita, con concentrazioni plasmatiche massime che si verificano entro poche ore dopo la somministrazione, ed è metabolizzata principalmente nel fegato.
Formula:C17H14F3N3O2S
InChI:InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
InChI key:InChIKey=RZEKVGVHFLEQIL-UHFFFAOYSA-N
SMILES:C(F)(F)(F)C1=NN(C(=C1)C2=CC=C(C)C=C2)C3=CC=C(S(N)(=O)=O)C=C3
Sinonimi:- 4-[5-((4-Methylphenyl)-3-TRIFLUORPMETHYL)-1H-pyrazol-YL]BENENESULFONAMIDE
- 4-[5-(4-Methylphenyl)-3-(Trifluoromethyl)Pyrazol-1-Yl]Benzenesulfonamide
- 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
- 4-[5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
- 4-[[5-(4-Methylphenyl)-3-trifluoromethyl]-1H-pyrazol-yl]Benzenesulfonamide
- Benzenesulfonamide, 4-5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl-
- Celebra-
- Celebrex
- Celecox
- Celocoxib
- Eurocox
- Medicoxib
- Onsenal
- Sc 58635
- Xilebao
- Ym 177
- Vedi altri sinonimi
Ordinare per
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18 prodotti.
Celecoxib
CAS:Formula:C17H14F3N3O2SPurezza:>98.0%(T)(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:381.37Celecoxib
CAS:CelecoxibFormula:C17H14F3N3O2SPurezza:99.7%Colore e forma:WhitePeso molecolare:381.07588Celecoxib
CAS:Sulfonamides used as drugsFormula:C17H14F3N3O2SColore e forma:PowderPeso molecolare:381.07588Celecoxib
CAS:Celecoxib (SC 58635) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of celecoxib is as a Cyclooxygenase Inhibitor.Formula:C17H14F3N3O2SPurezza:99.44% - 99.98%Colore e forma:White PowderPeso molecolare:381.37Celecoxib
CAS:Formula:C17H14F3N3O2SPurezza:(Titration) 98.0 - 102.0 % (dried basis)Colore e forma:White or almost white powderPeso molecolare:381.37Celecoxib
CAS:Prodotto controllato<p>Applications Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.Celecoxib is used to treat pain or inflammation caused by many conditions such as arthritis, ankylosing spondylitis, and menstrual pain. Celecoxib is also used in the treatment of hereditary polyps in the colon<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Formula:C17H14F3N3O2SColore e forma:NeatPeso molecolare:381.37Celecoxib
CAS:Prodotto controllatoCelecoxib-BioX TM is a pyrazole derivative that acts as a selective COX-2 inhibitor. It has been shown to inhibit prostaglandin synthesis and promote apoptosis in human osteosarcoma cells. Celecoxib-BioX TM also inhibits tumor growth and inhibits angiogenesis in combination with paclitaxel, which is a chemotherapeutic agent. It is a nonsteroidal anti-inflammatory drug, thus a beneficial treatment in conditions such as rheumatoid arthritis, osteoarthritis, musculoskeletal pain, acute pain and juvenile rheumatoid arthritis. Furthermore it can be utilized in patients with familial adenomatous polyposis to reduce colon and rectal polyps.Formula:C17H14F3N3O2SPurezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:381.37 g/molCelecoxib - Bio-X ™
CAS:Prodotto controllato<p>Celecoxib is a pyrazole derivative that acts as a selective COX-2 inhibitor. It has been shown to inhibit prostaglandin synthesis and promote apoptosis in human osteosarcoma cells. Celecoxib also inhibits tumor growth and inhibits angiogenesis in combination with paclitaxel, which is a chemotherapeutic agent. It is a nonsteroidal anti-inflammatory drug, thus a beneficial treatment in conditions such as rheumatoid arthritis, osteoarthritis, musculoskeletal pain, acute pain and juvenile rheumatoid arthritis. Furthermore it can be utilized in patients with familial adenomatous polyposis to reduce colon and rectal polyps.<br>Celecoxib is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>Formula:C17H14F3N3O2SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:381.37 g/molCelecoxib-13C6
CAS:Prodotto controllatoFormula:C6C11H14F3N3O2SColore e forma:NeatPeso molecolare:387.328
