CAS 17321-77-6
:cloridrato di clomipramina
Descrizione:
cloridrato di clomipramina è un antidepressivo triciclico utilizzato principalmente nel trattamento del disturbo ossessivo-compulsivo (DOC) e di altri disturbi dell'umore. Funziona inibendo il riassorbimento dei neurotrasmettitori, in particolare serotonina e norepinefrina, aumentando così la loro disponibilità nella fessura sinaptica. Questo composto appare come una polvere cristallina bianca o bianco sporco ed è solubile in acqua, rendendolo adatto per somministrazione orale. cloridrato di clomipramina ha una emivita relativamente lunga, il che consente una somministrazione una volta al giorno in molti casi. Il suo profilo farmacologico include una gamma di effetti collaterali, come sedazione, secchezza delle fauci e potenziali effetti cardiovascolari, richiedendo un attento monitoraggio nei pazienti. La sostanza è classificata come un farmaco da prescrizione ed è soggetta a controlli normativi a causa del suo potenziale per effetti collaterali e interazioni con altri farmaci. In generale, cloridrato di clomipramina è un importante agente terapeutico in psichiatria, particolarmente per i pazienti con DOC resistente al trattamento.
Formula:C19H24Cl2N2
InChI:InChI=1/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H
InChI key:InChIKey=WIMWMKZEIBHDTH-UHFFFAOYSA-N
SMILES:C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=C(Cl)C2.Cl
Sinonimi:- 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
- 3-Chloro-5-(3-dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
- 3-Chloroimipramine hydrochloride
- 5H-Dibenz[b,f]azepine, 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
- 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
- 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride
- Anafranil
- Anaphranil
- Anatranil
- Chlorimipramine hydrochloride
- Chloroimipram-ine HCl
- Chloroimipramine monohydrochloride
- Clomipramine HCl
- ANAFRANIL HYDROCHLORIDE
- 5H-Dibenzb,fazepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride
- CLOMIPRAMINE HYDROCHLORIDE
- Clomipraminhydrochlorid
- 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride
- Chlomipramine
- 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-5h-dibenz[b,f]azepine monohydrochloride
- 3-chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(b,f)azepinemono
- 3-CHLORO-10,11-DIHYDRO-N,N-DIMETHYL-5H-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
- f)azepine,10,11-dihydro-3-chloro-5-(3-(dimethylamino)propyl)-5h-dibenz(mon
- f)azepine-5-propanamine,3-chloro-10,11-dihydro-n,n-dimethyl-5h-dibenz(mo
- CLOMIPRAMINE HYDROCHLORIDE \ SEROTONIN U PTAKE INHIBITOR, ANTIDEPRESSANT
- 3-chloroimipraminehydrochloride
- CHLOROIMIPRAMINE HYDROCHLORIDE
- Vedi altri sinonimi
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20 prodotti.
Clomipramine hydrochloride
CAS:<p>Potent, selective 5-HT uptake blocker</p>Formula:C19H24Cl2N2Colore e forma:White to pale yellow, Crystals or crystalline powderPeso molecolare:351.32Clomipramine hydrochloride
CAS:Clomipramine hydrochlorideFormula:C19H23ClN2HClPurezza:99.6%Colore e forma:White To Off-WhitePeso molecolare:350.13165Clomipramine Hydrochloride
CAS:<p>Antidepressants, tranquilizers and other psychotherapeu</p>Formula:C19H23ClN2·ClHColore e forma:White Yellow PowderPeso molecolare:351.31(3-{5-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)dimethylamine hydrochloride
CAS:Formula:C19H24Cl2N2Purezza:99%Colore e forma:SolidPeso molecolare:351.3133Clomipramine hydrochloride
CAS:<p>Clomipramine HCl (Anafranil) is a serotonin-inhibiting tricyclic antidepressant, well-absorbed and metabolized to desmethylclomipramine in the liver.</p>Formula:C19H23ClN2·HClPurezza:99.04% - 99.47%Colore e forma:White To Slightly Yellow Crystalline PowderPeso molecolare:351.31Clomipramine hydrochloride
CAS:<p>Clomipramine hydrochloride</p>Purezza:≥98%Peso molecolare:351.31g/molClomipramine-13C-d3 HCl
CAS:Formula:C1813CH20D3ClN2·HClColore e forma:White To Off-White SolidPeso molecolare:318.87 36.46Ref: 4Z-C-195011
5mgPrezzo su richiesta10mg1.335,00€25mg2.366,00€50mg3.944,00€100mgPrezzo su richiestaClomipramine Hydrochloride
CAS:<p>Clomipramine Hydrochloride</p>Purezza:99%Peso molecolare:351.31g/molClomipramine Hydrochloride
CAS:Prodotto controllatoFormula:C19H23ClN2·ClHColore e forma:NeatPeso molecolare:351.31Clomipramine Hydrochloride
CAS:Formula:C19H23ClN2·HClPurezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:351.32Clomipramine hydrochloride
CAS:Formula:C19H23ClN2·HClPurezza:98.0 - 102.0 % (dried basis)Colore e forma:White or almost white crystalline powderPeso molecolare:351.32Clomipramine Hydrochloride
CAS:Prodotto controllato<p>Applications Serotonin reuptake inhibitor. Antidepressant; antiobsessional agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Peters, M.D., et al.: Clin. Pharm., 9, 165 (1990), Adamczyk, M., et al.: Ther. Drug Monit., 17, 371 (1995), Poolsup, N., et al.: J. Clin. Pharm. Ther., 25, 197 (2000), Bose, D., et al.: J. Pharmacol. Toxicol. Methods, 52, 323 (2005),<br></p>Formula:C19H23ClN2·ClHColore e forma:White To Off-WhitePeso molecolare:351.31Clomipramine hydrochloride
CAS:Prodotto controllato<p>Clomipramine hydrochloride is the hydrochloride salt form of clomipramine, an amphiphilic drug, derivative of dibenzazepine. It is presumed that this tricyclic compound affects serotonin uptake in the brain increasing thus the activity of serotonin. Also, clomipramine reduces the re-uptake of norepinephrine (active metabolite desmethylclomipramine) and binds to alpha-adrenergic, histaminergic, and cholinergic receptors (side effects). Clomipramine is antidepressant, used to treat obsessive compulsive disorder, panic disorders and cataplexy. Clomipramine is shown to modulate immune activation, shows constant anti-inflammatory properties at therapeutic concentrations by consistently decreasing pro- inflammatory cytokines. Clomipramine could be a good candidate to counteract SARS-CoV-2 infection worsening thanks to its high penetration in the brain and its anti-inflammatory effects.</p>Formula:C19H24Cl2N2Purezza:Min. 95%Colore e forma:SolidPeso molecolare:351.31 g/molClomipramine hydrochloride - Bio-X ™
CAS:Prodotto controllato<p>Clomipramine is a tricyclic antidepressant drug that inhibits the reuptake of serotonin, norepinephrine, and dopamine. It is used to treat obsessive compulsive disorder, panic disorders and cataplexy. Additionally, Clomipramine is shown to modulate immune activation and shows constant anti-inflammatory properties at therapeutic concentrations by consistently decreasing pro-inflammatory cytokines.</p>Formula:C19H24Cl2N2Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:351.31 g/mol
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