CAS 17402-86-7

Benzo[b]thiophene, 4-nitro-, 1,1-dioxide

Formula: C₈H₅NO₄S

Sinonimi:

• PHGDH-IN-5
• PHGDH-IN-5 (Compound B12)
• Benzo[b]thiophene, 4-nitro-, 1,1-dioxide

PHGDH-IN-5

CAS: 17402-86-7

Compound B12 (PHGDH-IN-5) acts as a covalent inhibitor of PHGDH, demonstrating an IC50 value of 0.29 μM. It has been shown to inhibit the proliferation of cancer cell lines that overexpress PHGDH and reduce the production of glucose-derived serine in MDA-MB-468 cells [1].

Formula: C₈H₅NO₄S

Colore e forma: Solid

Peso molecolare: 211.20

Ref: TM-T87143