CAS 175481-36-4

Lacosamide

Descrizione:

Lacosamide è un composto farmaceutico utilizzato principalmente come anticonvulsivante nel trattamento dell'epilessia. È classificato come un amminoacido funzionalizzato ed è noto per la sua capacità di stabilizzare le membrane neuronali e inibire il fuoco neuronale ripetitivo. La formula chimica di Lacosamide è C15H18N2O2 e presenta una struttura unica che include un anello fenilico e un gruppo funzionale ammidico. Lacosamide agisce migliorando l'inattivazione dei canali sodici voltaggio-dipendenti, il che aiuta a ridurre l'eccitabilità dei neuroni. Viene tipicamente somministrato per via orale o endovenosa ed è ben assorbito nel tratto gastrointestinale. La sostanza ha un profilo farmacocinetico favorevole, con una emivita relativamente lunga, che consente una somministrazione una o due volte al giorno. Gli effetti collaterali comuni possono includere vertigini, nausea e mal di testa, ma generalmente è ben tollerato. Lacosamide è anche oggetto di indagine per un possibile utilizzo in altri disturbi neurologici, riflettendo il suo ampio potenziale terapeutico oltre l'epilessia.

Formula: C₁₃H₁₈N₂O₃

InChI: InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1

InChI key: InChIKey=VPPJLAIAVCUEMN-GFCCVEGCSA-N

SMILES: C(NC([C@H](NC(C)=O)COC)=O)C1=CC=CC=C1

Sinonimi:

• (2R)-2-(Acetylamino)-3-methoxy-N-(phenylmethyl)propanamide
• (2R)-2-Acetamido-N-benzyl-3-methoxypropanamide
• (2R)-2-acetamido-N-benzyl-3-methoxy-propanamide
• (R)-2-Acetamido-N-benzyl-3-methoxypropionamide
• (R)-2-acetamido-N-benzyl-3-methoxypropanamide
• Add 243037
• Erlosamide
• Harkoseride
• Lacosamide UCB
• Lacoset
• Lacoset 50
• N~2~-acetyl-N-benzyl-O-methyl-D-serinamide
• Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)-
• Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (R)-
• Spm 927

Lacosamide

CAS: 175481-36-4

Formula: C₁₃H₁₈N₂O₃

Purezza: >98.0%(HPLC)

Peso molecolare: 250.30

Ref: 3B-L0430

LACOSAMIDE FOR SYSTEM SUITABILITY CRS

CAS: 175481-36-4

LACOSAMIDE FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0001973

Lacosamide

CAS: 175481-36-4

Formula: C₁₃H₁₈N₂O₃

Purezza: (HPLC) ≥ 98.0%

Colore e forma: White to off-white powder

Peso molecolare: 250.29

Ref: 7W-GP3690

Lacosamide

CAS: 175481-36-4

Formula: C₁₃H₁₈N₂O₃

Colore e forma: White To Off-White Solid

Peso molecolare: 250.30

Ref: 4Z-L-281

Lacosamide-d3 (Acetyl-d3)

CAS: 175481-36-4

Formula: C₁₃H₁₅N₂O₃D₃

Colore e forma: White To Off-White Solid

Peso molecolare: 253.32

Ref: 4Z-L-283

(2R)-Lacosamide-d3 (O-methyl-d3)

CAS: 1217689-95-6, 175481-36-4

Purezza: 99 atom % D

Colore e forma: White Solid

Peso molecolare: 253.32

Ref: 3U-D7271

Lacosamide 1.0 mg/ml in Acetonitrile

Prodotto controllato

CAS: 175481-36-4

Formula: C₁₃H₁₈N₂O₃

Colore e forma: Single Solution

Peso molecolare: 250.29

Ref: 61-AMP3640.00-11

Lacosamide

Prodotto controllato

CAS: 175481-36-4

Formula: C₁₃H₁₈N₂O₃

Colore e forma: Neat

Peso molecolare: 250.29

Ref: 86-MM3640.00

Lacosamide

CAS: 175481-36-4

Formula: C₁₃H₁₈N₂O₃

Colore e forma: Off-White

Peso molecolare: 250.29

Ref: 61-FOR3640.00

Lacosamide

Prodotto controllato

CAS: 175481-36-4

Applications Lacosamide is a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lees, G., et al.: Brain Res., 612, 190 (1993), Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997), Barton, M., et al.: Epilepsy Res., 47, 217 (2001), Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006), Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007),

Formula: C₁₃H₁₈N₂O₃

Colore e forma: Neat

Peso molecolare: 250.29

Ref: TR-L098500

Lacosamide

CAS: 175481-36-4

Formula: C₁₃H₁₈N₂O₃

Peso molecolare: 250.30

Ref: ST-EA-CP-L8000

Lacosamide - Bio-X ™

Prodotto controllato

CAS: 175481-36-4

Lacosamide is a drug that is used for the treatment of epilepsy. It has been shown to inhibit neuronal death in vitro and in animal models, and has been extensively studied for its potential benefits in the treatment of bowel disease. The mechanism of action for lacosamide involves inhibition of the transport of neurotransmitters from the synaptic cleft by binding to the neuronal sodium channels and increasing their recovery rate. Lacosamide has also been found to affect energy metabolism by inhibiting the activity of mitochondrial enzymes such as matrix effect and complex I/III.

Formula: C₁₃H₁₈N₂O₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 250.29 g/mol

Ref: 3D-BL164605

Lacosamide

Prodotto controllato

CAS: 175481-36-4

Lacosamide is a drug that is used for the treatment of epilepsy. It has been shown to inhibit neuronal death in vitro and in animal models, and has been extensively studied for its potential benefits in the treatment of bowel disease. The mechanism of action for lacosamide involves inhibition of the transport of neurotransmitters from the synaptic cleft by binding to the neuronal sodium channels and increasing their recovery rate. Lacosamide has also been found to affect energy metabolism by inhibiting the activity of mitochondrial enzymes such as matrix effect and complex I/III.

Formula: C₁₃H₁₈N₂O₃

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 250.29 g/mol

Ref: 3D-FL24825

Lacosamide-[13C,d3]

CAS: 175481-36-4

Formula: C₁₃H₁₈N₂O₃

Peso molecolare: 250.29

Ref: BE-MCD-7478

Lacosamide

CAS: 175481-36-4

Formula: C₁₃H₁₈N₂O₃

Peso molecolare: 250.29

Ref: BE-MU-7478

Lacosamide-d6

Prodotto controllato

CAS: 175481-36-4

Applications Labelled Lacosamide (L098500). Lacosamide is a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.
References Lees, G., et al.: Brain Res., 612, 190 (1993), Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997), Barton, M., et al.: Epilepsy Res., 47, 217 (2001), Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006), Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007),

Formula: C₁₃D₆H₁₂N₂O₃

Colore e forma: Neat

Peso molecolare: 256.331

Ref: TR-L098503

Lacosamide

Prodotto controllato

CAS: 175481-36-4

Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof, nesoi

Formula: C₁₃H₁₈N₂O₃

Colore e forma: White Light Yellow Powder

Peso molecolare: 250.13174

Ref: 45-1357103