CAS 1781882-72-1

Formula: C16H24Cl2N8O

InChI: InChI=1S/C16H22N8O.2ClH/c1-2-24-14-10(8-20-11-3-5-18-6-4-11)7-19-9-12(14)21-16(24)13-15(17)23-25-22-13;;/h7,9,11,18,20H,2-6,8H2,1H3,(H2,17,23);2*1H

InChI key: NRRCQHARLPNLHJ-UHFFFAOYSA-N

SMILES: CCN1C2=C(C=NC=C2CNC3CCNCC3)N=C1C4=NON=C4N.Cl.Cl

SB-747651A Dihydrochloride

CAS: 1781882-72-1

SB-747651A Dihydrochloride

Formula: C₁₆H₂₄Cl₂N₈O

Purezza: 98%

Peso molecolare: 415.32

Ref: 54-BUP11893

SB-747651A (dihydrochloride)

CAS: 1781882-72-1

Formula: C₁₆H₂₄Cl₂N₈O

Peso molecolare: 415.3208

Ref: IN-DA01ENO0

SB 747651A Dihydrochloride

Prodotto controllato

CAS: 1781882-72-1

Formula: C₁₆H₂₂N₈O•2(HCl)

Colore e forma: Neat

Peso molecolare: 415.32

Ref: TR-S154635

SB 747651A dihydrochloride

CAS: 1781882-72-1

SB 747651A dihydrochloride is a small molecule that inhibits the response element-binding protein (RBP) and thus prevents activation of transcription factors. It has been shown to reduce intestinal inflammation in mice by inhibiting the release of inflammatory mediators. SB 747651A dihydrochloride also inhibits the production of cyclic AMP, which may be responsible for its anti-inflammatory properties. This drug is able to inhibit the proliferation of intestinal tissue cells, but not pancreatic cells, suggesting it may be effective in treating patients with ulcerative colitis or Crohn's disease.

Formula: C₁₆H₂₄Cl₂N₈O

Purezza: Min. 95%

Peso molecolare: 415.3 g/mol

Ref: 3D-GWC88272

SB-747651A Dihydrochloride

CAS: 1781882-72-1

SB-747651A dihydrochloride, an MSK1 inhibitor (IC50=11 nM), also targets PRK2, RSK1, p70S6K, ROCK-II; potential in inflammation study.

Formula: C₁₆H₂₄Cl₂N₈O

Purezza: 98.05%

Colore e forma: Solid

Peso molecolare: 415.32

Ref: TM-T9652