CAS 18194-24-6

1,2-dimiristoil-sn-glicero-3-fosfocolina monoidrato

Descrizione:

1,2-dimiristoil-sn-glicero-3-fosfocolina monoidrato, comunemente noto come DMPC, è un fosfolipide che svolge un ruolo cruciale nella formazione delle membrane biologiche. È caratterizzato dalle sue due catene di acidi grassi miristilici, che contribuiscono alle sue proprietà idrofobiche, e da un gruppo testa di colina che conferisce idrofobicità. Questa natura anfifilica consente al DMPC di formare bilayers in ambienti acquosi, rendendolo essenziale per la struttura e la funzione delle membrane cellulari. Il DMPC è tipicamente utilizzato nella ricerca di biochimica e biofisica, in particolare in studi che coinvolgono liposomi e dinamica delle membrane. Ha una temperatura di transizione di fase relativamente alta, che influisce sulla sua fluidità e stabilità nei sistemi di membrana. Come monoidrato, contiene una molecola d'acqua per molecola di DMPC, influenzando le sue proprietà di solubilità e cristallizzazione. In generale, il DMPC è un componente vitale nello studio della biologia delle membrane e dei sistemi di somministrazione dei farmaci, fornendo informazioni sulle interazioni lipidiche e sull'organizzazione delle membrane.

Formula: C₃₆H₇₂NO₈P

InChI: InChI=1/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m1/s1

InChI key: InChIKey=CITHEXJVPOWHKC-UUWRZZSWSA-N

SMILES: [C@H](OC(CCCCCCCCCCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCCCCCCCC)=O

Sinonimi:

• (2S)-2,3-bis(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
• (R)-(7-Myristoyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphatricosyl)trimethylammonium-4-oxid
• (R)-(7-myristoyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphatricosyl)trimethylammonium 4-oxide
• 1,2-<span class="text-smallcaps">L</span>-α-Dimyristoylphosphatidylcholine
• 1,2-Bis(myristoyl)-sn-glycerophosphocholine
• 1,2-Dimyristoyl-3-sn-phosphatidylcholine
• 1,2-Dimyristoyl-<span class="text-smallcaps">L</span>-3-phosphatidylcholine
• 1,2-Dimyristoyl-<span class="text-smallcaps">L</span>-phosphatidylcholine
• 1,2-Dimyristoyl-<span class="text-smallcaps">L</span>-α-phosphatidylcholine
• 1,2-Dimyristoyl-L-3-phosphatidylcholine
• 1,2-Dimyristoyl-L-phosphatidylcholine
• 1,2-Dimyristoyl-L-α-phosphatidylcholine
• 1,2-Dimyristoyl-Sn-Glycero-3-Phosphocholine
• 1,2-Dimyristoyl-sn-3-glycerophosphocholine
• 1,2-Dimyristoyl-sn-glycero-3-phosphatidylcholine
• 1,2-Dimyristoyl-sn-glycero-3-phosphocholine monohydrate
• 1,2-Dimyristoyl-sn-glycero-3-phosphorylcholine
• 1,2-Dimyristoyl-sn-glycero-phosphocholine
• 1,2-Dimyristoyl-sn-glycerol-3-phosphocholine
• 1,2-Dimyristoyl-sn-glycerol-3-phosphorylcholine
• 1,2-Dimyristoyl-sn-glycerophosphocholine
• 1,2-Dimyristoyl-sn-phosphatidylcholine
• 1,2-Dimyristoylphosphatidylcholine
• 1,2-Ditetradecanoyl-sn-glycero-3-phosphocholine
• 1,2-Ditetradecanoyl-sn-glycero-3-phosphorylcholine
• 1,2-L-α-Dimyristoylphosphatidylcholine
• 1,2-Myristoyl-sn-glycero-3-phosphocholine
• 3,5,9-Trioxa-4-phosphatricosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxotetradecyl)oxy]-, hydroxide, inner salt, 4-oxide, (R)-
• 3,5,9-Trioxa-4-phosphatricosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxotetradecyl)oxy]-, inner salt, 4-oxide, (7R)-
• 3,5,9-Trioxa-4-phosphatricosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxotetradecyl)oxy]-, inner salt, 4-oxide, (R)-
• 4-oxido de (R)-(7-miristoil-4-oxido-10-oxo-3,5,9-trioxa-4-fosfatricosil)trimetilamonio
• 4-oxyde de (R)-(7-myristoyl-4-oxydo-10-oxo-3,5,9-trioxa-4-phosphatricosyl)trimethylammonium
• 50: PN: WO2017201317 SEQID: 123 claimed RNA
• <span class="text-smallcaps">L</span>-1,2-Dimyristoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-Dimyristoyllecithin
• <span class="text-smallcaps">L</span>-Dimyristoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-α-Dimyristoyllecithin
• <span class="text-smallcaps">L</span>-α-Dimyristoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-β,γ-Dimyristoyl-α-lecithin
• <span class="text-smallcaps">L</span>-β,γ-Dimyristoyl-α-phosphatidylcholine
• Anatrace
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dimyristin, <span class="text-smallcaps">L</span>-
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dimyristin, L-
• Choline, phosphate, ester with <span class="text-smallcaps">L</span>-1,2-dimyristin
• Choline, phosphate, ester with L-1,2-dimyristin
• Dimyristoyl Lecithin
• Dimyristoyl sn-3-phosphatidylcholine
• Dimyristoyl-3-sn-phosphatidylcholine
• Dimyristoyl-<span class="text-smallcaps">L</span>-α-glycerophosphocholine
• Dimyristoyl-<span class="text-smallcaps">L</span>-α-lecithin
• Dimyristoyl-<span class="text-smallcaps">L</span>-α-phosphatidylcholine
• Dimyristoyl-L-α-glycerophosphocholine
• Dimyristoyl-L-α-lecithin
• Dimyristoyl-L-α-phosphatidylcholine
• Dimyristoyl-sn-glycero-3-phosphocholine
• Dimyristoylphosphatidylcholine
• Ditetradecanoyllecithin
• Dmpc
• L-1,2-Dimyristoylphosphatidylcholine
• L-A-phosphatidylcholine dimyristoyl
• L-Dimyristoyllecithin
• L-Dimyristoylphosphatidylcholine
• L-a-Lecithin-b,g-dimyristoyl = b,g-Dimyristoyl-L-a-Lecithin = Dimyristoyl-L-a-Lecithin = Dimyristoyl-L-3-Lecithin
• L-α-Dimyristoyllecithin
• L-α-Dimyristoylphosphatidylcholine
• L-β,γ-Dimyristoyl-α-lecithin
• L-β,γ-Dimyristoyl-α-phosphatidylcholine
• [(2R)-2,3-di(tetradecanoyloxy)propyl] 2-(trimethylammonio)ethyl phosphate
• sn-3-Dimyristoyllecithin
• β,γ-Dimyristoyl <span class="text-smallcaps">L</span>-α-phosphatidylcholine
• β,γ-Dimyristoyl L-α-phosphatidylcholine
• 1,2-Dimyristoyl-SN-Glycero-3-Phospho-Choline-D54
• 1,2-Ditetradecanoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-dimyristoyl, L-β,γ-Dimyristoyl-α-lecithin
• 14:0 PC
• L-ALPHA-PHOSPHATIDYLCHOLINE, DIMYRISTOYL (C14:0)
• DIMYRISTOYL-L-3-LECITHIN
• dimyristoyl
• L-BETA,GAMMA-DIMYRISTOYL-ALPHA-LECITHIN
• DIMYRISTOYL-L-3-LECITHIN Synthetic
• BETA-GAMMA-DIMYRISTOYL-L-ALPHA-LECITHIN
• L-ALPHA-PHOSPHATIDYLCHOLINE, DIMYRISTOYL
• Lecithin-b,g-Dimyristoyl-L-a-=Dimyristoyl-L-a-L

1,2-Dimyristoyl-sn-glycero-3-phosphocholine

CAS: 18194-24-6

Formula: C₃₆H₇₂NO₈P

Purezza: >97.0%(HPLC)(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 677.94

Ref: 3B-D3924

1,2-Dimyristoyl-sn-glycero-3-phosphocholine

CAS: 18194-24-6

Bachem ID: 4005627.

Formula: C₃₆H₇₂NO₈P

Purezza: > 98%

Colore e forma: White Powder

Peso molecolare: 677.94

Ref: 01-4005627

1,2-Dimyristoyl-sn-glycero-3-phosphocholine

CAS: 18194-24-6

1,2-Dimyristoyl-sn-glycero-3-phosphocholine

Formula: C₃₆H₇₂NO₈P

Purezza: ≥98%

Peso molecolare: 677.93

Ref: 54-BUP17225

DMPC

CAS: 18194-24-6

DMPC

Formula: C₃₆H₇₂NO₈P

Purezza: 95%

Peso molecolare: 677.95

Ref: 54-BIPG2303

Dimyristoylphosphatidylcholine

CAS: 18194-24-6

Dimyristoylphosphatidylcholine

Formula: C₃₆H₇₂NO₈P

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 677.94

Ref: 54-OR1012962

1,2-Dimyristoyl-sn-glycero-3-phosphocholine

CAS: 18194-24-6

Formula: C₃₆H₇₂NO₈P

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 677.9325

Ref: IN-DA007U9H

1,2-Dimyristoyl-sn-glycero-3-phosphocholine

CAS: 18194-24-6

Formula: C₃₆H₇₂NO₈P

Purezza: ≥ 98.0%

Colore e forma: White powder

Peso molecolare: 677.93

Ref: 7W-GK8173

1,2-Dimyristoyl-sn-Glycero-3-Phosphatidylcholine

CAS: 18194-24-6

Formula: C36H72NO8P

Purezza: >99%

Colore e forma: Solid

Peso molecolare: 677.93

Ref: 48-37-1400

1,2-Dimyristoyl-sn-glycero-3-phosphocholine

CAS: 18194-24-6

DMPC is a synthetic phospholipid for studying lipid layers in liposomes.

Formula: C₃₆H₇₂NO₈P

Purezza: 99.16% - 99.95%

Colore e forma: White Powder

Peso molecolare: 677.93

Ref: TM-T9525

1,2-Dimyristoyl-sn-glycero-3-phosphocholine

CAS: 18194-24-6

(R)-2,3-Bis(tetradecanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate

Formula: C₃₆H₇₂NO₈P

Purezza: 98%

Peso molecolare: 677.93

Ref: IN-DG53376

1,2-Dimyristoyl-sn-glycero-3-phosphocholine

CAS: 18194-24-6

Applications 1,2-Dimyristoyl-sn-glycero-3-phosphocholine is used in the generation of micelles and liposomes.
References Høyrup, P., et al.: Biochim. Biophys. Acta, 1515, 133 (2001); Heberle, F., et al.: Cold Spring Harb Perspect Biol., 3, 1 (2011)

Formula: C₃₆H₇₂NO₈P

Colore e forma: Neat

Peso molecolare: 677.93

Ref: TR-D493590

(R)-2,3-Bis(tetradecanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate

CAS: 18194-24-6

Purezza: 98%

Peso molecolare: 677.9450073

Ref: 10-F863167

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d9

Prodotto controllato

CAS: 18194-24-6

Formula: C₃₆D₉H₆₃NO₈P

Colore e forma: Neat

Peso molecolare: 686.988

Ref: TR-D493592

1,2-Dimyristoyl-sn-glycero-3-phosphocholine

CAS: 18194-24-6

Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a phospholipid that is found in the plasma membrane. DMPC is composed of one molecule of glycerol, two molecules of fatty acid, and one molecule of choline. It has been shown to be a model system for studying transfer reactions, such as those involved in nonsteroidal anti-inflammatory drugs. DMPC can form bilayers with other lipids such as dimyristoylphosphatidylcholine (DMPP) and phosphatidylcholine (PC). The phase transition temperature of DMPC has been determined to be about 37°C. This lipid is also a surfactant because it lowers the surface tension between two liquids or between a liquid and a solid. Dimyristoyl-sn-glycero-3-phosphocholine has been shown to bind to basic proteins and peptide hormones through

Formula: C₃₆H₇₂NO₈P

Purezza: Area-% Min. 95 Area-%

Colore e forma: White Powder

Peso molecolare: 677.93 g/mol

Ref: 3D-FD49407