CAS 183449-57-2

PIR-FEN-ARG-IST-ASP-SER-GLI-TIR-GLU-VAL-IST-IST-GLN-LIS-LEU-VAL-FEN-FEN-ALA-GLU-ASP-VAL-GLI-SER-ASN-LIS-GLI-ALA-ILE-ILE-GLI-LEU-MET-VAL-GLI-GLI-VAL-VAL-ILE-ALA TRIFLUOROACETATO

Descrizione:

La sostanza indicata come "PIR-FEN-ARG-IST-ASP-SER-GLI-TIR-GLU-VAL-IST-IST-GLN-LIS-LEU-VAL-FEN-FEN-ALA-GLU-ASP-VAL-GLI-SER-ASN-LIS-GLI-ALA-ILE-ILE-GLI-LEU-MET-VAL-GLI-GLI-VAL-VAL-ILE-ALA TRIFLUOROACETATO" con numero CAS 183449-57-2 è un composto peptidico. È costituita da una sequenza di amminoacidi, che sono i mattoni delle proteine, ed è caratterizzata dal suo specifico arrangiamento di questi amminoacidi, contribuendo alle sue proprietà uniche e funzioni biologiche. La presenza di trifluoroacetato indica che il composto è probabilmente in forma di sale, il che può influenzare la sua solubilità e stabilità. I peptidi come questo possono mostrare varie attività biologiche, inclusi ruoli nella segnalazione, attività enzimatica e interazioni cellulari. La sequenza specifica di amminoacidi può anche determinare la sua interazione con recettori o altre biomolecole, rendendolo di interesse nella ricerca biochimica e farmaceutica. In generale, le caratteristiche di questo composto sono definite dalla sua composizione di amminoacidi, sequenza e dalla presenza del gruppo trifluoroacetato.

Formula: C₁₉₆H₂₉₉N₅₃O₅₅S₁

InChI: InChI=1S/C196H299N53O55S/c1-27-104(20)159(188(296)212-89-146(259)220-126(70-96(4)5)174(282)229-125(65-69-305-26)172(280)242-153(98(8)9)186(294)210-85-143(256)207-86-148(261)241-155(100(12)13)191(299)246-158(103(18)19)192(300)249-160(105(21)28-2)193(301)218-109(25)195(303)304)248-194(302)161(106(22)29-3)247-163(271)107(23)216-144(257)87-208-164(272)118(50-39-41-66-197)224-181(289)135(79-141(200)254)235-185(293)139(92-251)222-147(260)90-211-187(295)154(99(10)11)243-184(292)137(81-152(268)269)236-170(278)123(59-63-149(262)263)223-162(270)108(24)217-173(281)129(72-110-44-33-30-34-45-110)232-177(285)131(74-112-48-37-32-38-49-112)238-189(297)157(102(16)17)245-183(291)127(71-97(6)7)230-166(274)119(51-40-42-67-198)225-169(277)122(57-61-140(199)253)227-178(286)132(76-114-82-203-93-213-114)234-180(288)134(78-116-84-205-95-215-116)239-190(298)156(101(14)15)244-171(279)124(60-64-150(264)265)228-175(283)128(75-113-53-55-117(252)56-54-113)221-145(258)88-209-165(273)138(91-250)240-182(290)136(80-151(266)267)237-179(287)133(77-115-83-204-94-214-115)233-167(275)120(52-43-68-206-196(201)202)226-176(284)130(73-111-46-35-31-36-47-111)231-168(276)121-58-62-142(255)219-121/h30-38,44-49,53-56,82-84,93-109,118-139,153-161,250-252H,27-29,39-43,50-52,57-81,85-92,197-198H2,1-26H3,(H2,199,253)(H2,200,254)(H,203,213)(H,204,214)(H,205,215)(H,207,256)(H,208,272)(H,209,273)(H,210,294)(H,211,295)(H,212,296)(H,216,257)(H,217,281)(H,218,301)(H,219,255)(H,220,259)(H,221,258)(H,222,260)(H,223,270)(H,224,289)(H,225,277)(H,226,284)(H,227,286)(H,228,283)(H,229,282)(H,230,274)(H,231,276)(H,232,285)(H,233,275)(H,234,288)(H,235,293)(H,236,278)(H,237,287)(H,238,297)(H,239,298)(H,240,290)(H,241,261)(H,242,280)(H,243,292)(H,244,279)(H,245,291)(H,246,299)(H,247,271)(H,248,302)(H,249,300)(H,262,263)(H,264,265)(H,266,267)(H,268,269)(H,303,304)(H4,201,202,206)

InChI key: KGOBZCKPDJHJMH-UHFFFAOYSA-N

SMILES: CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)N)NC(=O)C(CC3=CNC=N3)NC(=O)C(CC4=CNC=N4)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CC6=CNC=N6)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C8CCC(=O)N8

Sinonimi:

• (Glp3) Beta-Amyloid (3-42)
• [Pyr3]-Beta-Amyloid (3-42)
• (Pyr3)-Amyloid Beta-Protein (3-42)
• [Pyr3]-Amyloid Beta-Protein (Human, 3-42) Trifluoroacetate
• Pyr-Frhdsgyevhhqklvffaedvgsnkgaiiglmvggvvia
• (Pglu3)-Amyloid Beta-Protein*Fragment (3-42)
• [Pglu3]-Amyloid Β-Protein Fragment 3-42

(Pyr³)-Amyloid β-Protein (3-42)

CAS: 183449-57-2

Bachem ID: 4102120.

Formula: C₁₉₆H₂₉₉N₅₃O₅₅S

Purezza: 95.7%

Colore e forma: White

Peso molecolare: 4309.92

Ref: 01-4102120

(Pyr³)-Amyloid β-Protein (3-42)

CAS: 183449-57-2

(Pyr³)-Amyloid β-Protein (3-42) was found to be the predominant amyloid β-peptide structure deposited in human brain of Alzheimer’s disease and Down’s syndrome patients. Therefore, (Pyr³)-Aβ (3-42) is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits. Nussbaum et al. studies the Prion-like behaviour and tau-dependent cytotoxicity of the truncated Aβ sequence.

Formula: C₁₉₆H₂₉₉N₅₃O₅₅S

Purezza: 87.6%

Colore e forma: White

Peso molecolare: 4309.92

Ref: 01-4029424

(Pyr3)-Amyloid β-Protein (3-42)

CAS: 183449-57-2

(Pyr3)-Amyloid β-Protein (3-42) is the predominant amyloid β peptide structure found deposited in the brains of individuals with Alzheimer's disease and Down syndrome. It is thought that (Pyr3)-Amyloid β-Protein (3-42) accumulates in the brain, leading to the formation of insoluble amyloid β-peptide deposits.

Formula: C₁₉₆H₂₉₉N₅₃O₅₅S

Colore e forma: Solid

Peso molecolare: 4307.19498

Ref: TM-TP3407

[Pyr3]-Amyloid Beta-Protein (Human, 3-42)

CAS: 183449-57-2

[Pyr3]-Amyloid Beta-Protein (Human, 3-42) is a fragment of the human amyloid beta protein that inhibits ion channels and ligand-activated receptors. It has been shown to be an inhibitor of ion channel activity in vitro. [Pyr3]-Amyloid Beta-Protein (Human, 3-42) is a synthetic peptide that can be used as a research tool for investigating the effects of amyloid beta protein on cell biology.

Formula: C₁₉₆H₂₉₉N₅₃O₅₅S

Purezza: Min. 95%

Peso molecolare: 4,309.9 g/mol

Ref: 3D-PAB-4367-V

(Pyr³)-Amyloid B-protein (3-42) trifluoroacetate

CAS: 183449-57-2

Please enquire for more information about (Pyr³)-Amyloid B-protein (3-42) trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₉₆H₂₉₉N₅₃O₅₅S•(C₂HF₃O₂)x

Purezza: Min. 95 Area-%

Ref: 3D-FP183579