CAS 183499-56-1

Formula: C22H22Cl3N5O

InChI: InChI=1S/C22H20ClN5O.2ClH/c23-19-2-1-3-20(10-19)28-9-8-26(15-22(28)29)14-21-12-25-16-27(21)13-18-6-4-17(11-24)5-7-18;;/h1-7,10,12,16H,8-9,13-15H2;2*1H

InChI key: XNGJWEBJQJQXQR-UHFFFAOYSA-N

SMILES: C1CN(C(=O)CN1CC2=CN=CN2CC3=CC=C(C=C3)C#N)C4=CC(=CC=C4)Cl.Cl.Cl

L-778123 Dihydrochloride

CAS: 183499-56-1

Formula: C₂₂H₂₀ClN₅O·2HCl

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 478.80

Ref: 3B-L0337

L-778123 Dihydrochloride

CAS: 183499-56-1

L-778123 Dihydrochloride

Formula: C₂₂H₂₀ClN₅O·2HCl

Purezza: >98%

Peso molecolare: 478.8

Ref: 54-OR1078635

L-778123 Dihydrochloride

CAS: 183499-56-1

L-778123 blocks FPTase/GGPTase-I, halts Ki-Ras prenylation, has acceptable toxicity with radiotherapy in advanced pancreatic cancer.

Formula: C₂₂H₂₂Cl₃N₅O

Colore e forma: Solid

Peso molecolare: 478.802

Ref: TM-T70134

L-778123 Dihydrochloride

CAS: 183499-56-1

L-778123 is a potent, selective inhibitor of Kv1.3 potassium channels with excellent pharmacokinetics and tissue selectivity. It has been used for in vitro research to study the role of ion channels in cell biology and pharmacology, as well as for the development of new drugs to treat diseases such as epilepsy. L-778123 binds to the Kv1.3 channel and inhibits its activity by blocking the flow of potassium ions through it. The binding site on L-778123 is completely different from that on other analogues that have been studied. This peptide can also be used to study protein interactions and antibody activity.

Formula: C₂₂H₂₂Cl₃N₅O

Purezza: Min. 95%

Peso molecolare: 478.8 g/mol

Ref: 3D-IHA49956