CAS 1850276-58-2

Formula: C22H16N2O2

InChI: InChI=1S/C22H16N2O2/c1-15-12-13-24-18(14-15)23-19(16-8-4-2-5-9-16)20(24)22(26)21(25)17-10-6-3-7-11-17/h2-14H,1H3

InChI key: AHNNWZOVCRQAAH-UHFFFAOYSA-N

SMILES: CC1=CC2=NC(=C(N2C=C1)C(=O)C(=O)C3=CC=CC=C3)C4=CC=CC=C4

IRAK4-IN-4

CAS: 1850276-58-2

IRAK4-IN-4

Formula: C₂₂H₁₆N₂O₂

Purezza: ≥98%

Peso molecolare: 340.37

Ref: 54-BUP09231

IRAK4-IN-4

CAS: 1850276-58-2

IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4)

Formula: C₂₂H₁₆N₂O₂

Purezza: 99.52%

Colore e forma: White Solid

Peso molecolare: 340.37

Ref: TM-T11673

1-(7-Methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)-2-phenylethane-1,2-dione

CAS: 1850276-58-2

Formula: C₂₂H₁₆N₂O₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 340.3746

Ref: IN-DA01KKAV

IRAK4-IN-4

CAS: 1850276-58-2

1-(7-Methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)-2-phenylethane-1,2-dione

Formula: C₂₂H₁₆N₂O₂

Purezza: 99%

Peso molecolare: 340.37

Ref: IN-DG01171407

IRAK4-IN-4

CAS: 1850276-58-2

Purezza: 99%

Peso molecolare: 340.121

Ref: 10-F864390

IRAK4-IN-4

CAS: 1850276-58-2

IRAK4-IN-4 is a research tool for the study of IRAK4. It is an inhibitor that blocks the activity of IRAK4, which is a protein that plays an important role in the activation of NF-κB and MAP kinase pathways. The peptide has been shown to inhibit LPS-induced TNFα production in human monocytes and neutrophils, as well as IL-1β production in mouse macrophages. It has also been shown to inhibit the activation of NF-κB by inhibiting IKKα/β phosphorylation, which usually leads to inhibition of proteasomal degradation of IκBα. This peptide can be used in pharmacological studies as well as cell biology experiments.

Formula: C₂₂H₁₆N₂O₂

Purezza: Min. 95%

Peso molecolare: 340.4 g/mol

Ref: 3D-AZC27658