CAS 1871-22-3

Blu di tetrazolio

Descrizione:

Blu di tetrazolio, noto anche come cloruro di 2,3,5-trifeniltetrazolio (TTC), è un composto chimico comunemente utilizzato in applicazioni biologiche e biochimiche, in particolare nei saggi di vitalità cellulare. È un indicatore redox che subisce un cambiamento di colore al momento della riduzione, passando da una forma solubile gialla a un prodotto di formazano rosso insolubile in presenza di cellule vitali. Questa proprietà lo rende utile per valutare l'attività metabolica negli organismi viventi, poiché solo le cellule metabolicamente attive possono ridurre il sale di tetrazolio. Blu di tetrazolio è tipicamente utilizzato in microbiologia, istologia e varie applicazioni di ricerca per valutare la proliferazione cellulare e la citotossicità. Il composto è generalmente stabile in condizioni di laboratorio standard, ma deve essere maneggiato con cura, poiché può essere tossico a certe concentrazioni. La sua solubilità in acqua e solventi organici consente applicazioni versatili in diverse configurazioni sperimentali. In generale, Blu di tetrazolio è uno strumento prezioso nello studio dei processi cellulari e nella valutazione della salute cellulare.

Formula: C₄₀H₃₂N₈O₂·2Cl

InChI: InChI=1S/C40H32N8O2.2ClH/c1-49-37-27-31(23-25-35(37)47-43-39(29-15-7-3-8-16-29)41-45(47)33-19-11-5-12-20-33)32-24-26-36(38(28-32)50-2)48-44-40(30-17-9-4-10-18-30)42-46(48)34-21-13-6-14-22-34;;/h3-28H,1-2H3;2*1H/q+2;;/p-2

InChI key: InChIKey=MUUHXGOJWVMBDY-UHFFFAOYSA-L

SMILES: O(C)C1=C(N2[N+](=NC(=N2)C3=CC=CC=C3)C4=CC=CC=C4)C=CC(=C1)C5=CC(OC)=C(C=C5)N6[N+](=NC(=N6)C7=CC=CC=C7)C8=CC=CC=C8.[Cl-]

Sinonimi:

• 2,2′,5,5′-Tetraphenyl-3,3′-(3,3′-dimethoxy-4,4′-diphenylene)ditetrazolium chloride
• 2,2′-(m,m′-Dimethoxy-p,p′-biphenylene)bis(3,5-diphenyltetrazolium chloride)
• 2H-Tetrazolium, 2,2′-(3,3′-dimethoxy[1,1′-biphenyl]-4,4′-diyl)bis[3,5-diphenyl-, chloride (1:2)
• 2H-Tetrazolium, 2,2′-(3,3′-dimethoxy[1,1′-biphenyl]-4,4′-diyl)bis[3,5-diphenyl-, dichloride
• 2H-Tetrazolium, 3,3′-(3,3′-dimethoxy-4,4′-biphenylylene)bis[2,5-diphenyl-, dichloride
• 3,3-(3,3-Dimethoxy-4,4-biphenylene)bis(2,5-diphenyl-2H-tetrazolium chloride)
• 3,3′-(3,3′-Dimethoxy-4,4′-biphenylylene)bis[2,5-diphenyl-2H-tetrazolium chloride]
• 3,3′-Dianisolebis[4,4′-(3,5-diphenyl)tetrazolium chloride]
• BT (dye)
• BTC
• Blue Tetrazolium chloride
• Ditetrazolium chloride
• NSC 27623
• Tetrazole blue
• Tetrazolium Blue BT
• Tetrazolium Blue Chloride
• Tetrazolium blue

Blue Tetrazolium [for Biochemical Research]

CAS: 1871-22-3

Formula: C₄₀H₃₂Cl₂N₈O₂

Purezza: >95.0%(T)

Colore e forma: White to Amber powder to crystal

Peso molecolare: 727.65

Ref: 3B-B3581

Blue Tetrazolium

CAS: 1871-22-3

Formula: C₄₀H₃₂Cl₂N₈O₂

Purezza: >95.0%(T)

Colore e forma: White to Amber powder to crystal

Peso molecolare: 727.65

Ref: 3B-D0943

Blue Tetrazolium chloride

CAS: 1871-22-3

Blue Tetrazolium chloride is useful in the prepartion of DNA cation complexes and immunoadsorbents for anti-DNA antibodies. It is used in assay of reducing sugars. In combination with 4-nitrocatechol, tetrazolium blue chloride forms a ternary complex with molybdenum(VI) for extraction and spectropho

Formula: C₄₀H₃₆Cl₂N₈O₂

Colore e forma: Pale yellow to yellow, Powder

Peso molecolare: 731.68

Ref: 02-A12502

3,3'-Dianisole-4,4'-bis(3,5-diphenyltetrazolium chloride

CAS: 1871-22-3

3,3'-Dianisole-4,4'-bis(3,5-diphenyltetrazolium chloride

Formula: C₄₀H₃₂N₈O₂·2Cl

Purezza: ≥98%

Colore e forma: Pale yellow Solid-Powder

Peso molecolare: 727.64048

Ref: 54-BIT3025

Blue Tetrazolium

CAS: 1871-22-3

Blue Tetrazolium (Tetrazolium blue), a dye used in microbial research, can be reduced to blue tetrazolium formazan (BTF). It determines succinate dehydrogenase (SDH) activity in yeast strains as a reduced substrate. Extract BTF using DMSO and test its absorption spectrum. BTF exhibits a wavelength range of 480-600 nm with maximal absorbance at 540 nm ^[1].

Formula: C₄₀H₃₂Cl₂N₈O₂

Peso molecolare: 727.64

Ref: TM-T85863

Tetrazolium Blue Chloride

CAS: 1871-22-3

Formula: C₄₀H₃₂Cl₂N₈O₂

Purezza: (HPLC) ≥ 95.0%

Colore e forma: Yellow powder

Peso molecolare: 727.66

Ref: 7W-GT7170

3,3'-(3,3'-DIMETHOXY-[1,1'-BIPHENYL]-4,4'-DIYL)BIS(2,5-DIPHENYL-2H-TETRAZOL-3-IUM) CHLORIDE

CAS: 1871-22-3

Formula: C₄₀H₃₂Cl₂N₈O₂

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 727.6405

Ref: IN-DA007S1S

Tetrazolium Blue Chloride (>90%)

Prodotto controllato

CAS: 1871-22-3

Stability Light Sensitive
Applications Tetrazolium Blue Chloride is used for its anti-plasmodium activity. Also used in the study of inhibition of diphenyltetrazolium bromide (MTT) reduction by β-amyloid peptides resulting in neurodegenerative manifestations. Dyes and metabolites.
References Cui, X. et al.: Bioorg, Med. Chem., 16, 1927 (2008); Shearman, M. et al.: J. Neurochem, 65, 218 (1995);

Formula: C₄₀H₃₂N₈O₂·2Cl

Purezza: >90%

Colore e forma: Neat

Peso molecolare: 727.6

Ref: TR-T310700

Tetrazolium blue chloride

CAS: 1871-22-3

Tetrazolium blue chloride is a chemical compound that is used in the diagnosis of leukemia. It is a tetrazolium salt that reacts with reduced nicotinamide adenine dinucleotide (NADH) and produces an insoluble blue product. Tetrazolium blue chloride has been shown to be effective in treating human leukemic cells by causing DNA damage, which leads to cell death. Tetrazolium blue chloride has also been found to be an anti-inflammatory agent due to its ability to inhibit prostaglandin synthesis and production of reactive oxygen species.

Formula: C₄₀H₃₂N₈O₂·2Cl

Purezza: 90 To 110%

Colore e forma: Yellow Powder

Peso molecolare: 727.64 g/mol

Ref: 3D-ET11162

Blue Tetrazolium Chloride (BTC, Tetrazolium Blue Chloride) extrapure AR

CAS: 1871-22-3

Formula: C₄₀H₃₂O₂N₈Cl₂

Colore e forma: Lemon yellow, Crystalline powder, Clear, Yellow

Peso molecolare: 727.66

Ref: SR-22649