CAS 19210-12-9
:Arpagoside
Descrizione:
Arpagoside è un glicoside iridoide che si trova naturalmente principalmente nelle radici della pianta Harpagophytum procumbens, comunemente nota come artiglio del diavolo. È caratterizzato dalla sua formula molecolare, che include atomi di carbonio, idrogeno e ossigeno, riflettendo la sua struttura glicosidica. Arpagoside è noto per le sue potenziali proprietà antinfiammatorie e analgesiche, rendendolo di interesse nella medicina erboristica e negli integratori alimentari, in particolare per condizioni come l'artrite e il dolore articolare. Il composto presenta un sapore amaro ed è spesso estratto per l'uso in varie formulazioni. In termini di solubilità, Arpagoside è generalmente solubile in acqua e solventi organici, il che facilita la sua estrazione e incorporazione in vari prodotti. I suoi effetti farmacologici sono attribuiti alla sua capacità di modulare le vie infiammatorie e influenzare la percezione del dolore. Come molti composti naturali, l'efficacia e la sicurezza di Arpagoside possono variare in base al dosaggio e alla risposta individuale, rendendo necessaria ulteriore ricerca per comprendere appieno il suo potenziale terapeutico e i meccanismi d'azione.
Formula:C24H30O11
InChI:InChI=1S/C24H30O11/c1-23(35-16(27)8-7-13-5-3-2-4-6-13)11-15(26)24(31)9-10-32-22(20(23)24)34-21-19(30)18(29)17(28)14(12-25)33-21/h2-10,14-15,17-22,25-26,28-31H,11-12H2,1H3/b8-7+/t14-,15-,17-,18+,19-,20-,21+,22+,23+,24-/m1/s1
InChI key:InChIKey=KVRQGMOSZKPBNS-FMHLWDFHSA-N
SMILES:O[C@@]12[C@@]([C@](OC(/C=C/C3=CC=CC=C3)=O)(C)C[C@H]1O)([C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC=C2)[H]
Sinonimi:- (1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-Hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
- (1S,4aS,5R,7S,7aS)-1-(beta-D-glucopyranosyloxy)-4a,5-dihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-7-yl (2E)-3-phenylprop-2-enoate
- (1S-(1alpha,4aalpha,5alpha,7alpha(E),7aalpha))-1,4a,5,6,7,7a-Hexahydro-4a,5-dihydroxy-7-methyl-7-((allyl-1-oxo-3-phenyl)oxy)cyclopenta(c)pyran-1-yl-beta-D-glucopyranoside
- 1-(Hexopyranosyloxy)-4A,5-Dihydroxy-7-Methyl-1,4A,5,6,7,7A-Hexahydrocyclopenta[C]Pyran-7-Yl 3-Phenylprop-2-Enoate
- E-Harpagoside
- Hapagoside
- Harpagoside
- β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl
- β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propenyl]oxy]cyclopenta[c]pyran-1-yl
- β-<span class="text-smallcaps">D</span>-Glucopyranoside, 1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[(1-oxo-3-phenyl-2-propenyl)oxy]cyclopenta[c]pyran-1-yl, [1S-[1α,4aα,5α,7α(E),7aα]]-
- β-D-Glucopyranoside, (1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propenyl]oxy]cyclopenta[c]pyran-1-yl
- (1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-Hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl β-D-glucopyranoside
- β-D-Glucopyranoside, (1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl
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Harpagoside
CAS:Harpagoside analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C24H30O11Purezza:(HPLC) ≥98%Colore e forma:PowderPeso molecolare:494.49Ref: IN-DA0074IX
1gPrezzo su richiesta1mg43,00€5mg62,00€25mg129,00€50mg140,00€100mg171,00€250mg314,00€Harpagoside
CAS:Harpagoside has anti-inflammatory effects, it blocks lipopolysaccharide (LPS)-induced bone loss in an inflammatory osteoporosis model, and it does not prevent ovariectomy-mediated bone erosion in a postmenopausal osteoporosis model, it may lead to a partial prevention of obesity-induced atherosclerosis by attenuating inflammatory responses. Harpagoside suppresses lipopolysaccharide-induced iNOS and COX-2 expression through inhibition of NF-κB activation. Harpagoside exerts neuroprotection effect and ameliorates learning and memory deficit appears to be associated, at least in part, with up-regulation of brain-derived neurotrophic factor (BDNF) content as well as activating its downstream signaling pathways, e.g., MAPK/PI3K pathways.Formula:C24H30O11Purezza:95%~99%Peso molecolare:494.493Harpagoside
CAS:Formula:C24H30O11Purezza:>95.0%(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:494.49Harpagoside (Standard)
CAS:Harpagoside (Standard) is a reference standard for research and analysis in studies involving Harpagoside. 1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression of cyclooxygenase-2 and inducible nitric oxide in HepG2 cells.Formula:C24H30O11Peso molecolare:494.49Harpagoside
CAS:(1S,4aS,5R,7S,7aS)-4a,5-Dihydroxy-7-methyl-1-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-7-yl cinnamateFormula:C24H30O11Purezza:99%Peso molecolare:494.49Ref: 4Z-H-063002
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaHarpagoside
CAS:Harpagoside: anti-inflammatory; 3 mM inhibits seed germination; reduces COX-2, iNOS mRNA, and protein in HepG2.Formula:C24H30O11Purezza:99.71% - ≥95%Colore e forma:White SolidPeso molecolare:494.49Harpagoside
CAS:Natural glycosideFormula:C24H30O11Purezza:≥ 95.0 % (HPLC)Colore e forma:PowderPeso molecolare:494.5Harpagoside
CAS:Applications Harpagoside is an iridoid glycoside along with with Harpagide (H105270), the potential to be strong anti-inflammatory agents providing the bulk of the observed effects from their plant origins.
References Zhang, L. et al.: Bioorg Med. Chem., 19, 4882 (2011); Wen, B. et al.: J. Ethnopharm., 147, 503 (2013);Formula:C24H30O11Colore e forma:NeatPeso molecolare:494.49Harpagoside
CAS:Harpagoside is a bioactive compound, which is an iridoid glycoside derived from the root of the plant Harpagophytum procumbens, commonly known as Devil’s Claw. This compound is predominantly sourced from Southern Africa, where the plant is native to semi-arid regions and has been traditionally used in herbal medicine.Formula:C24H30O11Purezza:Min. 95%Colore e forma:PowderPeso molecolare:494.5 g/molHarpagoside-D5
CAS:Prodotto controllatoApplications Harpagoside-D5 is an isotope labelled analog of Harpagoside (H105275). Harpagoside is an iridoid glycoside along with with Harpagide (H105270), the potential to be strong anti-inflammatory agents providing the bulk of the observed effects from their plant origins.
References Zhang, L. et al.: Bioorg Med. Chem., 19, 4882 (2011); Wen, B. et al.: J. Ethnopharm., 147, 503 (2013);Formula:C24D5H25O11Colore e forma:NeatPeso molecolare:499.519
