CAS 2022-85-7

Flucitosina

Descrizione:

Flucitosina, con il numero CAS 2022-85-7, è un farmaco antifungino utilizzato principalmente per trattare infezioni fungine gravi, in particolare quelle causate da specie di Candida e Cryptococcus. È un analogo della pirimidina che interferisce con la sintesi degli acidi nucleici inibendo la timidilato sintasi, interrompendo infine la sintesi di DNA e RNA fungini. Flucitosina viene tipicamente somministrato insieme ad altri agenti antifungini, come l'amfotericina B, per aumentarne l'efficacia e ridurre il rischio di resistenza. La sostanza è ben assorbita quando assunta per via orale ed è ampiamente distribuita nel corpo, incluso il sistema nervoso centrale, rendendola efficace nel trattamento della meningite criptococcica. Flucitosina è generalmente ben tollerato, ma può causare effetti collaterali come soppressione del midollo osseo e disturbi gastrointestinali. Il suo utilizzo richiede un attento monitoraggio della funzione renale e dei conteggi ematici a causa della potenziale tossicità. In generale, Flucitosina è uno strumento prezioso nell'arsenale antifungino, particolarmente per i pazienti immunocompromessi.

Formula: C₄H₄FN₃O

InChI: InChI=1/C4H4FN3O/c5-8-2-1-3(6)7-4(8)9/h1-2H,(H2,6,7,9)

InChI key: InChIKey=XRECTZIEBJDKEO-UHFFFAOYSA-N

SMILES: NC1=C(F)C=NC(=O)N1

Sinonimi:

• 2(1H)-Pyrimidinone, 4-amino-5-fluoro-
• 2(1H)-Pyrimidinone, 6-amino-5-fluoro-
• 2-Hydroxy-4-Amino-5-Fluoropyrimidine
• 4-Amino-5-Fluoro-2(1H)-Pyrimidinone
• 4-Amino-5-fluoro-2(1H)-pyrmidinone
• 4-Amino-5-fluoropyrimidin-2(1H)-one
• 4-Amino-5-fluoropyrimidin-2-ol
• 4-amino-1-fluoropyrimidin-2(1H)-one
• 5-Flucytosine
• 5-Fluoro Cytosine
• 5-Fluorocystosine
• 5-Fluorocytosin
• 5-Fluorocytosine
• 6-Amino-2-oxo-5-fluoropyrimidine
• 6-Amino-5-fluoro-2(1H)-pyrimidinone
• 6-amino-5-fluoropyrimidin-2(1H)-one
• Alcobon
• Ancobon
• Ancotil
• Ancotyl
• Cytosine, 5-fluoro-
• Flucitosina
• Flucylosine
• Flucytosin
• Flucytosine
• Fluocytosine
• Nsc 103805
• Ro 2-9915
• Toca FC
• 5-FC
• TIMTEC-BB SBB000061
• 4-AMINO-5-FLUORO-3H-PYRIMIDIN-2-ONE
• FLUCYSTINE
• fluorocytosine
• 4-amino-5-fluoro-2(1h)-pyrimidinon
• 4-AMINO-5-FLUORO-2(1H)-PYRIMIDINE

5-Fluorocytosine

CAS: 2022-85-7

Formula: C₄H₄FN₃O

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 129.09

Ref: 3B-F0321

5-Fluorocytosine, 98+%

CAS: 2022-85-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄H₄FN₃O

Purezza: 98+%

Colore e forma: White, crystalline powder

Peso molecolare: 129.09

Ref: 02-L16496

Flucytosine 2.0 mg/ml in Methanol

CAS: 2022-85-7

Colore e forma: Single Solution

Ref: 61-AMP0355.00-07

Flucytosine

CAS: 2022-85-7

Colore e forma: Neat

Ref: 61-FOR0355.00

FLUCYTOSINE RS

CAS: 2022-85-7

FLUCYTOSINE RS

Formula: C₄H₄FN₃O

Peso molecolare: 129.0925

Ref: 41-ICRS0310

FLUCYTOSINE CRS

CAS: 2022-85-7

FLUCYTOSINE CRS

Formula: C₄H₄FN₃O

Colore e forma: Crystalline Powder. White. Powder.

Peso molecolare: 129.0925

Ref: 41-F0175000

FLUCYTOSINE FOR SYSTEM SUITABILITY CRS

CAS: 2022-85-7

FLUCYTOSINE FOR SYSTEM SUITABILITY CRS

Formula: C₄H₄FN₃O

Peso molecolare: 129.0925

Ref: 41-Y0001262

Flucytosine

CAS: 2022-85-7

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Formula: C₄H₄FN₃O

Colore e forma: White Off-White Crystalline Powder

Peso molecolare: 129.03384

Ref: 45-1272000

Flucytosine

CAS: 2022-85-7

Flucytosine

Formula: C₄H₄FN₃O

Purezza: ≥98%

Colore e forma: Solid

Peso molecolare: 129.09

Ref: 54-BUP19221

Flucytosine

CAS: 2022-85-7

Flucytosine (NSC 103805) is a pyrimidine compound and a fluorinated cytosine analog exhibiting antifungal activity.

Formula: C₄H₄FN₃O

Purezza: 98.76% - 99.28%

Colore e forma: White Crystalline Solid Solid

Peso molecolare: 129.09

Ref: TM-T0986

5-Fluorocytosine

CAS: 2022-85-7

5-Fluorocytosine

Formula: C₄H₄FN₃O

Purezza: 97%

Colore e forma: White Solid-Powder

Peso molecolare: 129.09246

Ref: 54-PC3735

2(1H)-Pyrimidinone, 6-amino-5-fluoro-

CAS: 2022-85-7

Formula: C₄H₄FN₃O

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 129.0925

Ref: IN-DA002851

Flucytosine

CAS: 2022-85-7

Formula: C₄H₄FN₃O

Peso molecolare: 129.09

Ref: 4Z-F-422

5-Fluorocytosine

CAS: 2022-85-7

Formula: C₄H₄FN₃O

Purezza: ≥ 98.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 129.09

Ref: 7W-GA6771

Flucytosine

CAS: 2022-85-7

Colore e forma: Neat

Ref: 04-C13700500

Flucytosine

CAS: 2022-85-7

Formula: C₄H₄FN₃O

Colore e forma: Neat

Peso molecolare: 129.09

Ref: 86-MM0355.00

5-Fluorocytosine

CAS: 2022-85-7

Purezza: 97%

Peso molecolare: 129.09

Ref: FT-F14483

5-Fluoro Cytosine

Prodotto controllato

CAS: 2022-85-7

Applications 5-FC is a toxic antifungal/antimicrobial agent.
References Gopinath, P., et al.: Biotechnol. Lett., 30, 1913 (2008), Kalkanci, A., et al.: Microbiol Immunol., 52, 435 (2008), Dubeau, M., et al.: App. Env. Microbiol., 75, 1211 (2009),

Formula: C₄H₄FN₃O

Colore e forma: Neat

Peso molecolare: 129.09

Ref: TR-F589000

Cytosine-13C,15N2

CAS: 2022-85-7

Formula: CC₃H₅₁₅N₂NO

Colore e forma: Neat

Peso molecolare: 114.08

Ref: TR-C998952

5-Fluorocytosine

CAS: 2022-85-7

Flucytosine is an antifungal agent that inhibits the synthesis of DNA by preventing the conversion of deoxyuridine monophosphate to uracil monophosphate. It is used as an antiretroviral therapy in combination with other drugs, such as zidovudine and dideoxyinosine, to treat HIV infections. Flucytosine has been shown to have a strong antitumor response in a model system involving mice with sarcoma 180. This drug can cause serious side effects, including drug interactions and resistance mutations in microorganisms. These side effects are often observed in patients undergoing cancer chemotherapy or immunosuppressive therapy.

Formula: C₄H₄FN₃O

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 129.09 g/mol

Ref: 3D-FF02813