CAS 2055765-77-8

Pyrido[2,3-d]pyrimidin-5(8H)-one, 4-[[(1S)-1-(4,8-dichloro-1,2-dihydro-1-oxo-2-phenyl-3-isoquinolinyl)ethyl]amino]-

Formula: C₂₄H₁₇Cl₂N₅O₂

InChI: InChI=1S/C24H17Cl2N5O2/c1-13(30-23-19-17(32)10-11-27-22(19)28-12-29-23)21-20(26)15-8-5-9-16(25)18(15)24(33)31(21)14-6-3-2-4-7-14/h2-13H,1H3,(H2,27,28,29,30,32)/t13-/m0/s1

InChI key: HIXUFHUKIOTXLJ-ZDUSSCGKSA-N

SMILES: C[C@@H](C1=C(C2=C(C(=CC=C2)Cl)C(=O)N1C3=CC=CC=C3)Cl)NC4=NC=NC5=C4C(=O)C=CN5

Sinonimi:

• PI3K-IN-51
• Pyrido[2,3-d]pyrimidin-5(8H)-one, 4-[[(1S)-1-(4,8-dichloro-1,2-dihydro-1-oxo-2-phenyl-3-isoquinolinyl)ethyl]amino]-

PI3K-IN-51

CAS: 2055765-77-8

PI3K-IN-51, characterized as a PI3K inhibitor, exhibits IC50 values below 500 nM for p120γ and p110δ/p85α (WO2016204429A1; Example 10) [1].

Formula: C₂₄H₁₇Cl₂N₅O₂

Peso molecolare: 478.33

Ref: TM-T87157