CAS 2059952-75-7

Formula: C28H29NO6

InChI: InChI=1S/C28H29NO6/c1-31-23-14-20(15-24(18-23)32-2)7-6-19-8-11-22(12-9-19)29-27(30)13-10-21-16-25(33-3)28(35-5)26(17-21)34-4/h6-18H,1-5H3,(H,29,30)/b7-6+,13-10+

InChI key: KOZAEBHIXYBHKA-FCXQYMQBSA-N

SMILES: COC1=CC(=CC(=C1)/C=C/C2=CC=C(C=C2)NC(=O)/C=C/C3=CC(=C(C(=C3)OC)OC)OC)OC

STAT3-IN-1

CAS: 2059952-75-7

STAT3-IN-1 selective and orally active inhibitor of STAT3(in HT29 and MDA-MB 231 cells, with IC50 values of 1.82 μM and 2.14 μM , respectively), induces tumor

Formula: C₂₈H₂₉NO₆

Purezza: 95.89% - 98.13%

Colore e forma: Solid

Peso molecolare: 475.533

Ref: TM-T13009

STAT3-IN-1

CAS: 2059952-75-7

STAT3-IN-1

Formula: C₂₈H₂₉NO₆

Purezza: ≥95%

Peso molecolare: 475.53

Ref: 54-BUP08899

(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide

CAS: 2059952-75-7

(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide

Formula: C₂₈H₂₉NO₆

Purezza: 98%

Peso molecolare: 475.53

Ref: 54-OR1023168

(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide

CAS: 2059952-75-7

Formula: C₂₈H₂₉NO₆

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 475.5330

Ref: IN-DA01KL6K

STAT3-IN-1

CAS: 2059952-75-7

(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide

Formula: C₂₈H₂₉NO₆

Purezza: 98%

Peso molecolare: 475.53

Ref: IN-DG01126330

(E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide

CAS: 2059952-75-7

Purezza: 98%

Peso molecolare: 475.5409851

Ref: 10-F864415

STAT3-IN-1

CAS: 2059952-75-7

STAT3-IN-1 is a small molecule that inhibits the activation of the transcription factor STAT3. STAT3 is involved in the regulation of cancer cell proliferation and survival, as well as the suppression of inflammation. STAT3-IN-1 has been shown to inhibit tumor growth by blocking IL-10 production and attenuating tissue inhibitor of metalloproteinase (TIMP)-1 expression. It also inhibits chemoresistance in breast cancer cells by reducing NF-κB activity, which leads to increased apoptosis and decreased proliferation rates. Additionally, STAT3-IN-1 has been shown to reduce tumor size in mice xenografts, enhance tissue regeneration and improve prognosis.

Formula: C₂₈H₂₉NO₆

Purezza: Min. 95%

Peso molecolare: 475.5 g/mol

Ref: 3D-JHD95275