
CAS 2089226-94-6
:Formula:C27H21FN2O3S
InChI:InChI=1S/C27H21FN2O3S/c1-4-16-12-21-22(13-20(16)17-6-5-7-18(11-17)34(28,32)33)27(2,3)26-24(25(21)31)19-9-8-15(14-29)10-23(19)30-26/h5-13,30H,4H2,1-3H3
InChI key:TWKWEBMGDALHPN-UHFFFAOYSA-N
SMILES:CCC1=CC2=C(C=C1C3=CC(=CC=C3)S(=O)(=O)F)C(C4=C(C2=O)C5=C(N4)C=C(C=C5)C#N)(C)C
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SRPKIN-1
CAS:SRPKIN-1 is a protein that is expressed in the kidneys and other tissues. It is a covalent inhibitor of the serine/threonine kinase SRPK, which regulates the transcription of genes involved in cell growth and proliferation, such as the production of erythropoietin. SRPKIN-1 has been shown to inhibit tumor growth and prolong survival in animal models for cancer, including neurodevelopmental cancers.
Formula:C27H21FN2O3SPurezza:Min. 95%Peso molecolare:472.5 g/molSRPKIN-1
CAS:SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).Formula:C27H21FN2O3SPurezza:98%Colore e forma:SolidPeso molecolare:472.531




