CAS 2095849-04-8
:Formula:C25H20F3N5O2
InChI:InChI=1S/C25H20F3N5O2/c1-15-6-7-21(31-23(34)16-4-3-5-20(9-16)25(26,27)28)10-22(15)32-24(35)18-8-17(11-29-12-18)19-13-30-33(2)14-19/h3-14H,1-2H3,(H,31,34)(H,32,35)
InChI key:BMEXIUCHJUGPRB-UHFFFAOYSA-N
SMILES:CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)NC(=O)C3=CN=CC(=C3)C4=CN(N=C4)C
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CSF1R-IN-1
CAS:CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.Formula:C25H20F3N5O2Purezza:97.02% - 98.17%Colore e forma:SolidPeso molecolare:479.45385-(1-Methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide
CAS:5-(1-Methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamideFormula:C25H20F3N5O2Purezza:99%Peso molecolare:479.455-(1-Methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide
CAS:Formula:C25H20F3N5O2Purezza:99%Colore e forma:SolidPeso molecolare:479.45385-(1-Methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide
CAS:5-(1-Methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamideFormula:C25H20F3N5O2Purezza:99%Peso molecolare:479.45CSF1R-IN-1
CAS:CSF1R-IN-1 is a small molecule inhibitor, which is derived from synthetic chemical processes designed to selectively target the colony-stimulating factor 1 receptor (CSF1R) tyrosine kinase. The primary mode of action of CSF1R-IN-1 involves the inhibition of the CSF1R signaling pathway. This pathway is crucial for the regulation of the development and function of macrophages, which are vital for immune response and homeostasis. By selectively binding to the ATP-binding site of CSF1R, CSF1R-IN-1 effectively blocks the receptor's activity, thus reducing unwanted macrophage-mediated inflammation and proliferation.Formula:C25H20F3N5O2Purezza:Min. 95%Peso molecolare:479.5 g/mol
