CAS 211914-51-1

Dabigatran

Descrizione:

Dabigatran è un farmaco anticoagulante orale utilizzato principalmente per la prevenzione e il trattamento dei disturbi tromboembolici, come la fibrillazione atriale e la trombosi venosa profonda. Funziona come un inibitore diretto della trombina, il che significa che inibisce direttamente l'attività della trombina, un enzima cruciale per la formazione di coaguli di sangue. La formula chimica di Dabigatran è C19H21N7O5S e presenta una struttura unica che include un gruppo acido carbossilico, un gruppo amminico e un moiety sulfonamide. Dabigatran è caratterizzato dalla sua alta biodisponibilità e dal rapido inizio d'azione, rendendolo efficace per la gestione dei disturbi della coagulazione. Viene tipicamente somministrato come un pro-farmaco, Dabigatran etexilato, che viene convertito nella sua forma attiva nel corpo. La sostanza è nota per la sua farmacocinetica prevedibile, che consente una dosaggio fisso senza la necessità di monitoraggio routinario dei livelli di anticoagulazione, a differenza degli anticoagulanti tradizionali come la warfarina. Tuttavia, è essenziale considerare i potenziali effetti collaterali, inclusi i rischi di sanguinamento, e utilizzarlo sotto supervisione medica.

Formula: C₂₅H₂₅N₇O₃

InChI: InChI=1/C25H25N7O3/c1-31-20-10-7-17(25(35)32(13-11-23(33)34)21-4-2-3-12-28-21)14-19(20)30-22(31)15-29-18-8-5-16(6-9-18)24(26)27/h2-10,12,14,29H,11,13,15H2,1H3,(H3,26,27)(H,33,34)

InChI key: InChIKey=YBSJFWOBGCMAKL-UHFFFAOYSA-N

SMILES: CN1C=2C(=CC(C(N(CCC(O)=O)C3=CC=CC=N3)=O)=CC2)N=C1CNC4=CC=C(C(=N)N)C=C4

Sinonimi:

• 3-[[2-[[(4-Carbamimidoylphenyl)Amino]Methyl]-1-Methyl-Benzoimidazole-5-Carbonyl]-Pyridin-2-Yl-Amino]Propanoic Acid
• Bibr 953
• Bibr 953Zw
• Dabigatran
• N-(2-(4-(N-(Hexyloxycarbonyl)Amidino)Phenylaminomethyl)-1-Methyl-1H-Benzimidazol-5-Ylcarbonyl)-N-(2-Pyridyl)-Beta-Alanine Ethyl Ester
• N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine
• beta-alanine, N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-
• β-Alanine, N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-
• N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-ben...
• N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine
• Dabiga group
• BIBR953;BIBR 953;BIBR-953
• Dabigatran etexilate impurity1513
• 3-[[2-[[(4-carbaMiMidoylphenyl)aMino]Methyl]-1-Met
• BIBR 953 (Dabigatran, Pradaxa)
• Dabigatran(BIB-953
• Dabigatran Q: What is the CAS Number of
• BIB-953
• 3-(2-((4-carbamimidoylphenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid
• BIBR 953(Dabigatran)
• Dabigatran Etexilate Mesilate
• Dabigatran etexilate-1
• Dabigatran base
• 3-[[2-[[(4-carbaMiMidoylphenyl)aMino]Methyl]-1-Methyl-benzoiMidazole-5-carbonyl]-pyridin-2-yl-aMino]
• 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic
• Dabigatran3-(2-((4-carbamimidoylphenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid
• Dabigatran Ester Impurity B
• Dabigatran API
• BIBR 953;BIBR 953ZW;BIBR953;BIB-953
• Dabigatran Impurity U
• 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid
• 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid Dabigatran (BIBR 953)
• Dabigatran (Acid)
• ethyl 3-(2-(((4-(N'-((hexan-2-yloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate
• N-[[2-[[[4-(AMinoiMinoMethyl)phenyl]aMino]Methyl]-1-Methyl-1H-benzo[d]iMidazol-5-yl]carbonyl]-N-pyridin-2-yl-beta-alanine
• DabigatranQ: What is
• Dabigatran (BIBR 953)
• Dabigatran etexilate impurity189
• Dabigatran Impurity b
• N- (2-{ (4-carbaMiMidoylphenyl)aMino Methyl}-1-Met
• Dabigatran Q: What are the applications of
• Dabigatran Q: What is the storage condition of
• Dabigatran USP/EP/BP
• CS-1864
• N-[(2-{[(4-carbaMiMidoylphenyl)aMino]Methyl}-1-Methyl-1HbenziMidazol-

Dabigatran

CAS: 211914-51-1

Formula: C₂₅H₂₅N₇O₃

Purezza: >95.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 471.52

Ref: 3B-D5902

3-(2-(((4-Carbamimidoylphenyl)Amino)Methyl)-1-Methyl-N-(Pyridin-2-Yl)-1H-Benzo[D]Imidazole-5-Carboxamido)Propanoic Acid

CAS: 211914-51-1

3-(2-(((4-Carbamimidoylphenyl)Amino)Methyl)-1-Methyl-N-(Pyridin-2-Yl)-1H-Benzo[D]Imidazole-5-Carboxamido)Propanoic Acid

Formula: C₂₅H₂₅N₇O₃

Purezza: 98%

Peso molecolare: 471.51

Ref: 54-OR1010625

Dabigatran-13C-d3

CAS: 211914-51-1

Formula: C₂₄₁₃CH₂₂D₃N₇O₃

Colore e forma: White To Off-White Solid

Peso molecolare: 475.53

Ref: 4Z-D-59109

N-Nitroso Dabigatran Etexilate-13C-d3

CAS: 211914-51-1

Formula: C₃₃₁₃CH₃₇D₃N₈O₆

Colore e forma: White To Off-White Solid

Peso molecolare: 660.75

Ref: 4Z-D-59138

Dabigatran

CAS: 211914-51-1

Dabigatran

Formula: C₂₅H₂₅N₇O₃

Purezza: 98.5%

Peso molecolare: 471.51

Ref: 54-BUP05533

Dabigatran

CAS: 211914-51-1

Formula: C₂₅H₂₅N₇O₃

Colore e forma: White To Off-White Solid

Peso molecolare: 471.52

Ref: 4Z-D-591

Dabigatran (Standard)

CAS: 211914-51-1

Dabigatran (Standard) is a reference standard for research and analysis in studies involving Dabigatran. Dabigatran (BIBR 953ZW) is a THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation.

Formula: C₂₅H₂₅N₇O₃

Colore e forma: Solid

Peso molecolare: 471.5111

Ref: TM-TMSM-3464

Dabigatran

CAS: 211914-51-1

Formula: C₂₅H₂₅N₇O₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 471.5111

Ref: IN-DA00I41W

Dabigatran

CAS: 211914-51-1

Formula: C₂₅H₂₅N₇O₃

Colore e forma: Neat

Peso molecolare: 471.51

Ref: 86-MM3522.02

Dabigatran-d7 (>90%)

Prodotto controllato

CAS: 211914-51-1

Applications Dabigatran-d7, is the labeled analogue of Dabigatran (D100090), Nonpeptide, direct thrombin inhibitor. Antithrombotic.
References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002), Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002), Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005),

Formula: C₂₅H₁₈D₇N₇O₃

Purezza: >90%

Colore e forma: Neat

Peso molecolare: 478.55

Ref: TR-D100093

Dabigatran

CAS: 211914-51-1

Applications Nonpeptide, direct thrombin inhibitor. Antithrombotic.
References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002), Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002), Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005),

Formula: C₂₅H₂₅N₇O₃

Colore e forma: Neat

Peso molecolare: 471.51

Ref: TR-D100090

Dabigatran

CAS: 211914-51-1

3-(2-(((4-Carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid

Formula: C₂₅H₂₅N₇O₃

Purezza: 98%

Peso molecolare: 471.51

Ref: IN-DG158683

Dabigatran

CAS: 211914-51-1

Dabigatran (BIBR 953ZW), a thrombin inhibitor, prevents thrombus formation, reducing stroke and embolism risk in nonvalvular atrial fibrillation patients.

Formula: C₂₅H₂₅N₇O₃

Purezza: 97.44% - 98.71%

Colore e forma: Solid

Peso molecolare: 471.5111

Ref: TM-T6295

Dabigatran

CAS: 211914-51-1

Formula: C₂₅H₂₅N₇O₃

Peso molecolare: 471.51

Ref: ST-EA-CP-D5003

Dabigatran

CAS: 211914-51-1

Formula: C₂₅H₂₅N₇O₃

Peso molecolare: 471.5

Ref: BE-RMCD001000

Dabigatran

CAS: 211914-51-1

Formula: C₂₅H₂₅N₇O₃

Peso molecolare: 471.5

Ref: BE-MU-7354

DABIGATRAN

CAS: 211914-51-1

Purezza: 98%

Peso molecolare: 471.5209961

Ref: 10-F799805