CAS 2210298-14-7

LCB-2122

CAS: 2210298-14-7

LCB-2122 is an adenosine-like nucleoside analog featuring a C2'-stereoisomeric all-carbon quaternary carbon center. It inhibits doxorubicin-induced myocardial apoptosis with an IC50 value of 0.5 μM and also suppresses imatinib-induced apoptosis. LCB-2122 activates the AMPK signaling pathway, inducing the phosphorylation of AMPK and its downstream substrate acetyl-CoA carboxylase (ACC). Additionally, LCB-2122 alleviates mitochondrial damage caused by doxorubicin and is used in heart failure research.

Formula: C₁₆H₂₅ClN₅O₇P

Peso molecolare: 465.83

Ref: TM-T214622