CAS 2247544-02-9

Formula: C18H21Cl2N9S2

InChI: InChI=1S/C18H20ClN9S2.ClH/c1-12-10-15(30-18-22-24-25-27(18)9-8-26(2)3)28-16(20-12)21-17(23-28)29-11-13-4-6-14(19)7-5-13;/h4-7,10H,8-9,11H2,1-3H3;1H

InChI key: LJZUAAKUJAXXHQ-UHFFFAOYSA-N

SMILES: CC1=NC2=NC(=NN2C(=C1)SC3=NN=NN3CCN(C)C)SCC4=CC=C(C=C4)Cl.Cl

WS-383

CAS: 2247544-02-9

WS-383 is a selective, potent and reversible DCN1-UBC12 interaction inhibitor(IC50 of 11 nM).

Formula: C₁₈H₂₁Cl₂N₉S₂

Purezza: 98.46%

Colore e forma: Solid

Peso molecolare: 498.46

Ref: TM-T13349

WS-383

CAS: 2247544-02-9

Ref: IN-DA01V4OH

WS-383

CAS: 2247544-02-9

WS-383

Formula: C₁₈H₂₁Cl₂N₉S₂

Purezza: ≥98%

Peso molecolare: 498.46

Ref: 54-BUP12587

WS 383 hydrochloride

CAS: 2247544-02-9

Potent inhibitor of the interaction between defective cullin neddylation protein DCN1 and NEDD8-conjugating enzyme UBC12 with IC50 of 11 nM. WS 383 blocks the DCN1-UBC12 interaction in a reversible manner, selectively inhibits Cul3/1 neddylation and induces accumulation of p21, p27, and NRF2 proteins.

Formula: C₁₈H₂₀ClN₉S₂·HCl

Purezza: Min. 95%

Colore e forma: Solid

Peso molecolare: 498.46 g/mol

Ref: 3D-BW170250