CAS 2292-16-2

(-)-Neferina

Descrizione:

(-)-Neferina è un alcaloide che si trova naturalmente, estratto principalmente dai semi della pianta di loto, in particolare dalla specie *Nelumbo nucifera*. È caratterizzato dalla sua struttura chirale, che contribuisce alla sua attività biologica. Il composto presenta una gamma di proprietà farmacologiche, inclusi effetti anti-infiammatori, antiossidanti e potenzialmente neuroprotettivi. (-)-Neferina ha suscitato interesse nella chimica medicinale grazie alla sua capacità di modulare vari percorsi biologici, rendendolo un candidato per ulteriori ricerche in applicazioni terapeutiche. La sostanza è tipicamente studiata nel contesto della medicina tradizionale e della farmacologia moderna, con indagini in corso sui suoi meccanismi d'azione e sulla sua efficacia. La sua solubilità e stabilità possono variare a seconda del solvente e delle condizioni, il che è cruciale per la sua applicazione negli studi biologici. In generale, (-)-Neferina rappresenta un composto significativo nel campo dei prodotti naturali e della farmacognosia, evidenziando l'importanza delle sostanze derivate dalle piante nella scoperta di farmaci.

Formula: C₃₈H₄₄N₂O₆

InChI: InChI=1/C38H44N2O6/c1-39-15-14-27-21-36(44-5)38(23-30(27)31(39)17-24-7-10-28(42-3)11-8-24)46-34-19-25(9-12-33(34)41)18-32-29-22-37(45-6)35(43-4)20-26(29)13-16-40(32)2/h7-12,19-23,31-32,41H,13-18H2,1-6H3/t31-,32-/m1/s1

InChI key: InChIKey=MIBATSHDJRIUJK-ZWXJPIIXSA-N

SMILES: C([C@@H]1C=2C(=CC(OC)=C(OC3=CC(C[C@H]4C=5C(=CC(OC)=C(OC)C5)CCN4C)=CC=C3O)C2)CCN1C)C6=CC=C(OC)C=C6

Sinonimi:

• 4-[[(1R)-6,7-Dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol
• 4-[[(1S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]phenol
• 4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-2-{[(1R)-6-methoxy-1-(4-methoxybenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}phenol
• 4′′-O-Methylliensinine
• Methylliensinine
• Neferin
• Phenol, 4-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]-
• Neferine
• 4-[[(1R)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-6-methoxy-1-(4-methoxybenzyl)-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol
• Neferine USP/EP/BP
• 4-[(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)methyl]-2-[[1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methylisoquinolin-7-yl]oxy]phenol

Neferine

CAS: 2292-16-2

Neferine

Formula: C₃₈H₄₄N₂O₆

Purezza: ≥98%

Peso molecolare: 624.77

Ref: 54-BUP06165

Neferine

CAS: 2292-16-2

Formula: C₃₈H₄₄N₂O₆

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 624.7658

Ref: IN-DA002LIY

Neferine

CAS: 2292-16-2

Formula: C₃₈H₄₄N₂O₆

Peso molecolare: 624.78

Ref: 7W-GY2445

4-(((S)-6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl)-2-(((R)-6-Methoxy-1-(4-Methoxybenzyl)-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-7-Yl)Oxy)Phenol

CAS: 2292-16-2

4-(((S)-6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl)-2-(((R)-6-Methoxy-1-(4-Methoxybenzyl)-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-7-Yl)Oxy)Phenol

Formula: C₃₈H₄₄N₂O₆

Purezza: ≥98%

Colore e forma: Solid

Peso molecolare: 624.77

Ref: 54-OR1023075

Neferine

CAS: 2292-16-2

Neferine

Formula: C₃₈H₄₄N₂O₆

Purezza: 95%~99%

Peso molecolare: 624.778

Ref: BP-BP0987

Neferine

CAS: 2292-16-2

Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.

Formula: C₃₈H₄₄N₂O₆

Purezza: 98.81% - 99.65%

Colore e forma: White Solid

Peso molecolare: 624.77

Ref: TM-T5S1097

Neferine

CAS: 2292-16-2

Formula: C₃₈H₄₄N₂O₆

Peso molecolare: 624.78

Ref: 4Z-N-107001

Neferine

CAS: 2292-16-2

Neferine is an alkaloid, which is derived from the seeds of Nelumbo nucifera, commonly known as the lotus plant. This compound acts as a bioactive molecule with diverse pharmacological properties, primarily through its antioxidant and neuroprotective modes of action. Neferine functions by scavenging reactive oxygen species and inhibiting oxidative stress pathways, making it significant in cellular protection. Furthermore, it modulates various signaling pathways that are crucial for maintaining cellular homeostasis and survival.

Formula: C₃₈H₄₄N₂O₆

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 624.77 g/mol

Ref: 3D-FN65588

Neferine

CAS: 2292-16-2

Ref: BE-RMCN043000

Neferine

CAS: 2292-16-2

Formula: C₃₈H₄₄N₂O₆

Peso molecolare: 624.78

Ref: ST-EA-CP-N149000