CAS 2417987-45-0

Formula: C29H32ClF4N7O2

InChI: InChI=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32,33)34)15(2)11-20(35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17)4/h5,11-12,16-17H,1,6-10,13-14H2,2-4H3,(H2,35,36)/t16-,17-/m0/s1

InChI key: ZRBPIAWWRPFDPY-IRXDYDNUSA-N

SMILES: C[C@H]1CN(CCN1C2=NC(=NC3=C(C(=C(C=C32)Cl)C4=C(C(=CC(=N4)N)C)C(F)(F)F)F)OC[C@@H]5CCCN5C)C(=O)C=C

Divarasib

CAS: 2417987-45-0

Divarasib (GDC-6036), an investigational KRAS G12C inhibitor for solid tumors, has an IC50 of <0.01 μM.

Formula: C₂₉H₃₂ClF₄N₇O₂

Purezza: 98.72% - 99.83%

Colore e forma: White Solid

Peso molecolare: 622.057

Ref: TM-T9972

Divarasib

CAS: 2417987-45-0

Divarasib

Formula: C₂₉H₃₂ClF₄N₇O₂

Purezza: ≥98%

Colore e forma: Solid

Peso molecolare: 622.06

Ref: 54-BUP03614

1-[(3S)-4-[(7R)-7-[6-Amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-3-methyl-1-piperazinyl]-2-propen-1-one

CAS: 2417987-45-0

Purezza: 98%

Ref: IN-DA020M3B

Divarasib

CAS: 2417987-45-0

1-((S)-4-(7-((R)-6-Amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one

Formula: C₂₉H₃₂ClF₄N₇O₂

Purezza: 98%

Peso molecolare: 622.06

Ref: IN-DG01511960