CAS 2468065-01-0

Formula: C25H29ClN8O2S

InChI: InChI=1S/C25H29ClN8O2S/c1-15-5-3-6-17(26)22(15)32-23(35)19-14-28-25(37-19)31-20-13-21(30-16(2)29-20)33-9-11-34(12-10-33)24(36)18-7-4-8-27-18/h3,5-6,13-14,18,27H,4,7-12H2,1-2H3,(H,32,35)(H,28,29,30,31)/t18-/m0/s1

InChI key: MBQUHHCDYFJDRD-SFHVURJKSA-N

SMILES: CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)C(=O)[C@@H]5CCCN5

Pro-Dasatinib

CAS: 2468065-01-0

Pro-Dasatinib (compound 2j) is an amino acid analogue of Dasatinib and serves as a potent Src/Abl kinase inhibitor. It exhibits antiproliferative activity against K652 leukemia cancer cells, with an IC₅₀ of 0.21 nM.

Formula: C₂₅H₂₉ClN₈O₂S

Peso molecolare: 541.07

Ref: TM-T210759