CAS 2488851-89-2

Formula: C40H53BrFN9O13

InChI: InChI=1S/C40H53BrFN9O13/c41-29-26-27(4-5-30(29)42)46-37(48-56)35-36(50-64-49-35)45-9-8-43-10-12-57-14-16-59-18-20-61-22-24-63-25-23-62-21-19-60-17-15-58-13-11-44-31-3-1-2-28-34(31)40(55)51(39(28)54)32-6-7-33(52)47-38(32)53/h1-5,26,32,43-44,56H,6-25H2,(H,45,50)(H,46,48)(H,47,52,53)

InChI key: BVQZWOPTIZSOAW-UHFFFAOYSA-N

SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCOCCOCCOCCOCCOCCNCCNC4=NON=C4C(=NC5=CC(=C(C=C5)F)Br)NO

PROTAC IDO1 Degrader-1

CAS: 2488851-89-2

PROTAC IDO1 Degrader-1

Formula: C₄₀H₅₃BrFN₉O₁₃

Purezza: 98.17%

Peso molecolare: 966.8

Ref: 54-PC1027870

PROTAC IDO1 Degrader-1

CAS: 2488851-89-2

Purezza: 98.17%

Ref: IN-DA024X64

PROTAC IDO1 Degrader-1

CAS: 2488851-89-2

First potent PROTAC IDO1 degrader; links IDO1 to CRBN E3 ligase for UPS-induced degradation (DC50=2.84 μM), boosts H ER2 CAR-T cell efficacy.

Formula: C₄₀H₅₃BrFN₉O₁₃

Colore e forma: Solid

Peso molecolare: 966.816

Ref: TM-T37329