CAS 2597167-34-3

PROTAC Chk1 degrader-1

Formula: C₄₃H₄₄N₁₄O₉

InChI: InChI=1S/C43H44N14O9/c44-13-12-25-4-8-27(9-5-25)47-43-48-31(21-34(50-43)49-35-20-30(53-54-35)26-6-7-26)39(60)46-22-28-23-56(55-52-28)15-17-65-19-18-64-16-14-45-37(59)24-66-33-3-1-2-29-38(33)42(63)57(41(29)62)32-10-11-36(58)51-40(32)61/h1-5,8-9,20-21,23,26,32H,6-7,10-12,14-19,22,24H2,(H,45,59)(H,46,60)(H,51,58,61)(H3,47,48,49,50,53,54)

InChI key: HUEILOSTKICPMD-UHFFFAOYSA-N

SMILES: C1CC1C2=CC(=NN2)NC3=NC(=NC(=C3)C(=O)NCC4=CN(N=N4)CCOCCOCCNC(=O)COC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O)NC8=CC=C(C=C8)CC#N

Sinonimi:

• PROTAC Chk1 degrader-1

PROTAC Chk1 degrader-1

CAS: 2597167-34-3

Compound PROTAC-2, also known as PROTAC Chk1 degrader-1, is a potent degrader of Chk1, exhibiting a DC50 of 1.33 μM. It is utilized in cancer research [1].

Formula: C₄₃H₄₄N₁₄O₉

Colore e forma: Solid

Peso molecolare: 900.9

Ref: TM-T87262