CAS 2627-69-2

AICAr

Descrizione:

AICAr, o 5-aminoimidazolo-4-carbossamide ribonucleotide, è un composto chimico che gioca un ruolo significativo nel metabolismo cellulare, in particolare nella via di biosintesi delle purine. È un precursore nucleotidico coinvolto nella sintesi dell'adenosina monofosfato (AMP). AICAr è noto per i suoi potenziali effetti sul metabolismo energetico cellulare ed è stato studiato per il suo ruolo nell'attivazione della proteina chinasi attivata da AMP (AMPK), che è cruciale per regolare l'omeostasi energetica. Il composto è spesso indagato nel contesto dei disturbi metabolici, della fisiologia dell'esercizio e delle potenziali applicazioni terapeutiche per condizioni come l'obesità e il diabete di tipo 2. AICAr è tipicamente caratterizzato dalla sua struttura molecolare, che include un anello di imidazolo e un componente ribonucleotidico. Il suo numero CAS, 2627-69-2, è un identificatore unico che facilita l'identificazione e lo studio di questo composto nella letteratura scientifica e nelle banche dati. In generale, AICAr è una molecola significativa in biochimica con implicazioni per la salute e la gestione delle malattie.

Formula: C₉H₁₄N₄O₅

InChI: InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1

InChI key: InChIKey=RTRQQBHATOEIAF-UUOKFMHZSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(N)=C(C(N)=O)N=C2

Sinonimi:

• 1-Ribosyl-4-carboxamido-5-aminoimidazole
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-5-amino-4-imidazolecarboxamide
• 1H-Imidazole-4-carboxamide, 5-amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 5-Amino-1-beta-ribofuranosyl-imidazole-4-carboxamide
• 5-Amino-1-ribosyl-4-imidazolecarboxamide
• 5-Amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-imidazole-4-carboxamide
• 5-Amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosylimidazole-4-carboxamide
• 5-Amino-1beta-D-ribofuranosylimidazole-4-carboxamide
• 5-Amino-4-imidazolecarboxamide ribofuranoside
• 5-Amino-4-imidazolecarboxamide riboside
• 5-Aminoimidazole-4-carboxamid-1-β-<span class="text-smallcaps">D</span>-ribofuranoside
• 5-Aminoimidazole-4-carboxamide 1-(β-<span class="text-smallcaps">D</span>-ribofuranoside)
• 5-Aminoimidazole-4-carboxamide ribonucleoside
• 5-Aminoimidazole-4-carboxamide riboside
• 5-Aminoimidazole-4-carboxamide-1-§-D-Ribofuranoside
• 5-amino-1-(beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide
• AIC-Riboside
• AICA-riboside
• Acadra
• Aicar
• Arasine
• Gp 1-110
• Imidazole-4-carboxamide, 5-amino-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• NSC 105823
• 5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide
• 1H-Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-

5-Aminoimidazole-4-carboxamide 1-β-D-Ribofuranoside

CAS: 2627-69-2

Formula: C₉H₁₄N₄O₅

Purezza: >98.0%(HPLC)

Colore e forma: White to Light yellow to Light red powder to crystal

Peso molecolare: 258.23

Ref: 3B-A2528

5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside, 98%

CAS: 2627-69-2

Activator of AMP-activated protein kinase (AMPK)

Formula: C₉H₁₄N₄O₅

Purezza: 98%

Peso molecolare: 258.23

Ref: 02-J64720

AICAR

CAS: 2627-69-2

AICAR

Formula: C₉H₁₄N₄O₅

Purezza: ≥95%

Peso molecolare: 258.23

Ref: 54-BUP11706

AICAR

CAS: 2627-69-2

AICAR (Acadesine) is an AMPK activator, metabolic regulation, muscle function regulation, anti-cancer effect, neuroprotection. High-Quality, Low-Cost!

Formula: C₉H₁₄N₄O₅

Purezza: 98.00% - ≥95%

Colore e forma: Solid

Peso molecolare: 258.23

Ref: TM-T1477

5-Amino-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxamide

CAS: 2627-69-2

5-Amino-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxamide

Formula: C₉H₁₄N₄O₅

Purezza: 97%

Colore e forma: Colourless to pale yellow. Solid-Powder

Peso molecolare: 258.23126

Ref: 54-OR1170T

Acadesine

CAS: 2627-69-2

Formula: C₉H₁₄N₄O₅

Purezza: ≥ 98.0%

Colore e forma: White to beige solid

Peso molecolare: 258.23

Ref: 7W-GP6637

5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside

CAS: 2627-69-2

Applications AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)

Formula: C₉H₁₄N₄O₅

Colore e forma: Neat

Peso molecolare: 258.23

Ref: TR-A611700

5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranose

CAS: 2627-69-2

Acadesine is a purine nucleoside analogue that inhibits the synthesis of ATP in cells. Acadesine blocks phosphorylation of adenosine monophosphate (AMP) to adenosine triphosphate (ATP) by inhibiting the activity of kinase-3, an enzyme involved in the production of ATP. Acadesine also inhibits the release of ATP from muscle cells into the blood stream and preferentially targets kidney cells, thereby reducing renal injury. Acadesine has been shown to be effective at reducing proteinuria and improving renal function in rats with acute kidney injury. Acadesine also has anti-inflammatory properties due to its ability to inhibit proteins that are involved in inflammation.

Formula: C₉H₁₄N₄O₅

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 258.23 g/mol

Ref: 3D-NA03552

AICA Riboside

CAS: 2627-69-2

M04018 - AICA Riboside

Formula: C₉H₁₄N₄O₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 258.234

Ref: 10-M04018

5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside-15N4

Prodotto controllato

CAS: 2627-69-2

Applications A labelled nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)

Formula: C₉H₁₄₁₅N₄O₅

Colore e forma: Neat

Peso molecolare: 262.20

Ref: TR-A611703

Acadesine

CAS: 2627-69-2

Formula: C₉H₁₄N₄O₅

Peso molecolare: 258.23

Ref: ST-EA-CP-A354000