CAS 263707-16-0
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Trovati 8 prodotti.
ESI-09
CAS:2-(5-(tert-Butyl)isoxazol-3-yl)-N-(3-chlorophenyl)-2-oxoacetohydrazonoyl cyanideFormula:C16H15ClN4O2Purezza:98%Peso molecolare:330.77ESI-09
CAS:ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 μM, respectively.Formula:C16H15ClN4O2Purezza:97.24% - 99.57%Colore e forma:SolidPeso molecolare:330.77ESI 09
CAS:Prodotto controllatoApplications ESI 09 acts as an EPAC inhibitor, preventing EPAC-mediated insulin release form β-pancreatic cells. Selective control for EPAC over PKA and decreases migration and invasion of AsPc-1 and PANC-1 pancreatic cancer cells.
References Tao, X. et al.: J. Virol., 88, 3902 (2014); Almahariq, M. et al.: Mol. Pharm., 83, 122 (2013);Formula:C16H15ClN4O2Colore e forma:NeatPeso molecolare:330.769ESI-09
CAS:ESI-09 is a novel drug candidate that has been shown to have synergistic effects with chemotherapeutic agents in the treatment of cancer. It is a potential drug target for cancer, and its anticancer activity may be due to its ability to reduce oxidative stress by activating antioxidant enzymes. ESI-09 has antioxidative properties and decreases the mitochondrial membrane potential, which leads to increased ATP levels. ESI-09 also has the ability to cause cell death by inhibiting aerobic glycolysis, which may be due to its inhibitory effects on the polymerase chain reaction (PCR).Formula:C16H15ClN4O2Purezza:Min. 95%Peso molecolare:330.77 g/mol3-Isoxazolepropanenitrile, α-[2-(3-chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-β-oxo-
CAS:Formula:C16H15ClN4O2Purezza:98%Colore e forma:SolidPeso molecolare:330.7689
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