CAS 267234-08-2

N-(Phenylmethyl)glycylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysinamide

CAS: 267234-08-2

N-(Phenylmethyl)glycylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysinamide

Formula: C₆₁H₁₀₀N₂₂O₁₅

Purezza: 98%

Peso molecolare: 1381.59

Ref: 54-OR1138051

[Nphe1]Nociceptin(1-13)NH2

CAS: 267234-08-2

Competitive nociceptin receptor antagonist with pKi=8.4; no agonist activity; blocks nociceptin effects in vitro/in vivo.

Formula: C₆₁H₁₀₀N₂₂O₁₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 1381.6

Ref: TM-TP1987

[Nphe1]Nociceptin(1-13)NH2

CAS: 267234-08-2

Nociceptin is a neuropeptide of the tachykinin family that is primarily expressed in the brain. It has been shown to have an important role in long-term treatment of depression and pain. Nociceptin is a bifunctional molecule with both antinociceptive and excitatory effects. Its analgesic properties are mediated by its ability to inhibit the release of substance P and calcitonin gene-related peptide, which are neurotransmitters involved in pain transmission. Nociceptin also has excitatory effects on tissues such as the stomach, pancreas, heart, and bladder. It may also be able to reduce inflammation by inhibiting histamine release from mast cells.

Formula: C₆₁H₁₀₀N₂₂O₁₅

Purezza: Min. 95%

Peso molecolare: 1,381.6 g/mol

Ref: 3D-SKA23408