CAS 2771115-65-0

Formula: C30H31ClN4O5

InChI: InChI=1S/C30H31ClN4O5/c1-17(2)40-20-8-9-23(25(31)14-20)30(38)35-11-10-21-18(16-35)6-5-7-22(21)24(15-28(36)37)19-12-26-29(27(13-19)39-4)34(3)33-32-26/h5-9,12-14,17,24H,10-11,15-16H2,1-4H3,(H,36,37)

InChI key: SDTVNLLENIZMBI-UHFFFAOYSA-N

SMILES: CC(C)OC1=CC(=C(C=C1)C(=O)N2CCC3=C(C2)C=CC=C3C(CC(=O)O)C4=CC5=C(C(=C4)OC)N(N=N5)C)Cl

Keap1-Nrf2-IN-23

CAS: 2771115-65-0

Keap1-Nrf2-IN-23 (compound 56) acts as an inhibitor of the Keap1–Nrf2 PPI (IC50=16.0 nM). It exhibits a Kd value of 3.07 nM when binding to Keap1 and demonstrates oral activity.

Formula: C₃₀H₃₁ClN₄O₅

Colore e forma: Solid

Peso molecolare: 563.04

Ref: TM-T201064