
CAS 282101-98-8
:Formula:C4H2ClN3O3
InChI:InChI=1S/C4H2ClN3O3/c5-4-6-1-2(8(10)11)3(9)7-4/h1H,(H,6,7,9)
InChI key:YAWXGRKOOLHJSP-UHFFFAOYSA-N
SMILES:C1=C(C(=O)NC(=N1)Cl)[N+](=O)[O-]
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Percentuale di purezza
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100
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0
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50
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90
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95
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100
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2-Chloro-5-nitropyrimidin-4(1H)-one
CAS:2-Chloro-5-nitropyrimidin-4(1H)-oneFormula:C4H2ClN3O3Purezza:95+%Peso molecolare:175.532-Chloro-5-nitropyrimidin-4(1H)-one
CAS:2-Chloro-5-nitropyrimidin-4(1H)-oneFormula:C4H2ClN3O3Purezza:95+%Peso molecolare:175.532-Chloro-5-nitropyrimidin-4-ol
CAS:Prodotto controllatoApplications 2-Chloro-5-nitropyrimidin-4-ol is an intermediate used in the synthesis of 4-Chloro-5-nitro-2-(propylthio)pyrimidine (C374095), which is an impurity of the drug Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).
References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)Formula:C4H2ClN3O3Colore e forma:NeatPeso molecolare:175.53



