CAS 2848-96-6

Acetato di lorazepam

Descrizione:

Acetato di lorazepam, con il numero CAS 2848-96-6, è un derivato del lorazepam, un farmaco appartenente alla classe delle benzodiazepine. È caratterizzato principalmente dalle sue proprietà sedative, ansiolitiche e anticonvulsivanti, rendendolo utile nel trattamento dei disturbi d'ansia, dell'insonnia e nella gestione delle crisi. Il composto mostra un'alta affinità per il recettore GABA-A, potenziando gli effetti inibitori del neurotrasmettitore acido gamma-aminobutirrico (GABA) nel sistema nervoso centrale. Acetato di lorazepam viene tipicamente somministrato nella sua forma di acetato per migliorare la solubilità e la biodisponibilità. È una polvere cristallina bianca o bianco sporco, relativamente stabile in condizioni normali, ed è solubile in solventi organici come etanolo e dimetilsolfossido (DMSO). La farmacocinetica di Acetato di lorazepam implica un rapido assorbimento e distribuzione, con una emivita moderata, consentendo una gestione efficace degli episodi acuti di ansia. Come con altre benzodiazepine, si consiglia cautela a causa del potenziale di dipendenza e sintomi di astinenza con l'uso prolungato.

Formula: C₁₇H₁₂Cl₂N₂O₃

InChI: InChI=1/C17H12Cl2N2O3/c1-9(22)24-17-16(23)20-14-7-6-10(18)8-12(14)15(21-17)11-4-2-3-5-13(11)19/h2-8,17H,1H3,(H,20,23)

InChI key: InChIKey=CYDZMDOLVUBPNL-UHFFFAOYSA-N

SMILES: ClC1=C(C=2C=3C(NC(=O)C(OC(C)=O)N2)=CC=C(Cl)C3)C=CC=C1

Sinonimi:

• 2H-1,4-Benzodiazepin-2-one, 3-(acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-
• 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-, acetate
• 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-, acetate (ester)
• 3-(Acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
• 3-Acetoxy-7-chloro-5-(o-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
• 7-chloro-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl acetate
• Lorazepam acetate
• Ro 7-8407
• 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-2-oxo-2H-1,4-benzodiazepin-3-yl acetate
• [7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] ethanoate
• Acetic acid [7-chloro-5-(2-chlorophenyl)-2,3-dihydro-2-oxo-1H-1,4-benzodiazepin]-3-yl ester
• acetic acid [7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] ester
• CYDZMDOLVUBPNL-UHFFFAOYSA-N
• Lorazepam USP Related Compound A
• Lorazepam 3-acetate
• Lorazepam Related Compound A (25 mg) (7-Chloro-5-(ochlorophenyl)-1,3-dihydro-3-acetoxy-2H-1,4-benzodiazepin-2-one)
• Lorazepam Related Compound A (7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-acetoxy-2H-1,4-benzodiazepi (1370327)
• LorazepaM Related CoMpound A
• [7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] acetate

Lorazepam Related Compound A

CAS: 2848-96-6

Drugs with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

Formula: C₁₇H₁₂Cl₂N₂O₃

Colore e forma: Off-White Powder

Peso molecolare: 362.0225

Ref: 45-1370327

Lorazepam Acetate ((3RS)-7-Chloro-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl Acetate)

Prodotto controllato

CAS: 2848-96-6

Formula: C₁₇H₁₂Cl₂N₂O₃

Colore e forma: White Solid

Peso molecolare: 363.19

Ref: 61-FOR0071.07

(3RS)-7-Chloro-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-ylAcetate (Lorazepam Acetate)

Prodotto controllato

CAS: 2848-96-6

Formula: C₁₇H₁₂Cl₂N₂O₃

Colore e forma: Neat

Peso molecolare: 363.19

Ref: 86-MM0071.07

Lorazepam EP Impurity B

CAS: 2848-96-6

Formula: C₁₇H₁₂Cl₂N₂O₃

Peso molecolare: 363.19

Ref: ST-EA-CP-L85015

Lorazepam Acetate

Prodotto controllato

CAS: 2848-96-6

Formula: C₁₇H₁₂Cl₂N₂O₃

Colore e forma: Neat

Peso molecolare: 363.19

Ref: TR-L469840

3-(Acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Prodotto controllato

CAS: 2848-96-6

3-(Acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one is a drug that binds to human serum albumin. It is an enantiomer of lorazepam and is a specific ligand for α1 acid glycoprotein. This compound has been shown to be effective in the treatment of epilepsy and benzodiazepine withdrawal syndrome. It also has a cavity that can be used to bind reactive molecules such as carbamazepine. 3-(Acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin--2--one has been shown to have antitumour effects on cultured cells by inhibiting protein synthesis, thus leading to cell death.

Formula: C₁₇H₁₂Cl₂N₂O₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 363.19 g/mol

Ref: 3D-FA151720