CAS 28608-75-5

Orientina

Descrizione:

Orientina, con il numero CAS 28608-75-5, è un glicoside flavonoide trovato principalmente in varie piante, in particolare nelle foglie di alcune specie come il grano saraceno comune e in alcune erbe. È caratterizzato dal suo colore giallastro ed è noto per le sue proprietà antiossidanti, che contribuiscono ai suoi potenziali benefici per la salute. Orientina è solubile in acqua e presenta un sapore dolce grazie alla sua struttura glicosidica. Questo composto è spesso studiato per i suoi effetti farmacologici, comprese le attività anti-infiammatorie, anti-diabetiche e neuroprotettive. Inoltre, Orientina può svolgere un ruolo nella protezione delle cellule dallo stress ossidativo ed è stato indagato per il suo potenziale nel promuovere la salute cardiovascolare. La sua presenza in fonti alimentari suggerisce che potrebbe contribuire ai benefici generali per la salute associati a una dieta ricca di piante. Come molti flavonoidi, la biodisponibilità e l'efficacia di Orientina possono essere influenzate da vari fattori, incluso il metodo di estrazione e la presenza di altri composti nel materiale di origine.

Formula: C₂₁H₂₀O₁₁

InChI: InChI=1S/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1

InChI key: InChIKey=PLAPMLGJVGLZOV-VPRICQMDSA-N

SMILES: OC=1C(=C2C(C(=O)C=C(O2)C3=CC(O)=C(O)C=C3)=C(O)C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O

Sinonimi:

• (1S)-1,5-anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-D-glucitol
• 2-(3,4-Dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
• 2-(3,4-Dihydroxyphenyl)-8-β-<span class="text-smallcaps">D</span>-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
• 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-β-<span class="text-smallcaps">D</span>-glucopyranosyl-5,7-dihydroxy-
• 8-β-<span class="text-smallcaps">D</span>-Glucopyranosyl-3′,4′,5,7-tetrahydroxyflavone
• Luteolin 8-C-glucoside
• Luteolin 8-C-β-<span class="text-smallcaps">D</span>-glucopyranoside
• Luteolin 8-C-β-glucopyranoside
• Luteolin-8-glucoside
• Lutexin
• Orientin (flavone)
• Luteolin 8-C-β-D-glucopyranoside
• 2-(3,4-Dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
• Orientin

Orientin

CAS: 28608-75-5

Formula: C₂₁H₂₀O₁₁

Purezza: >98.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 448.38

Ref: 3B-O0503

2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-8-((2S,3R,4R,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl)-4H-Chromen-4-One

CAS: 28608-75-5

2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-8-((2S,3R,4R,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl)-4H-Chromen-4-One

Formula: C₂₁H₂₀O₁₁

Purezza: 99%

Peso molecolare: 448.38

Ref: 54-OR1009712

Orientin

CAS: 28608-75-5

Orientin

Formula: C₂₁H₂₀O₁₁

Purezza: 99.5%

Colore e forma: Solid

Peso molecolare: 448.38

Ref: 54-BUP11077

Orientin

CAS: 28608-75-5

Formula: C₂₁H₂₀O₁₁

Peso molecolare: 448.38

Ref: 4Z-O-107001

Orientin

CAS: 28608-75-5

Formula: C₂₁H₂₀O₁₁

Purezza: ≥ 97.0%

Colore e forma: Yellow powder

Peso molecolare: 448.38

Ref: 7W-GC4819

Orientin 100 µg/mL in Acetonitrile:Water

Prodotto controllato

CAS: 28608-75-5

Formula: C₂₁H₂₀O₁₁

Colore e forma: Single Solution

Peso molecolare: 448.38

Ref: 04-A15743000WL-100

Orientin

CAS: 28608-75-5

Formula: C₂₁H₂₀O₁₁

Colore e forma: Neat

Peso molecolare: 448.38

Ref: 04-C15743000

4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-

CAS: 28608-75-5

Formula: C₂₁H₂₀O₁₁

Purezza: 60%

Colore e forma: Solid

Peso molecolare: 448.3769

Ref: IN-DA002VV3

Orientin (Standard)

CAS: 28608-75-5

Orientin (Standard) is a reference standard for research and analysis in studies involving Orientin. 1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier integrity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. 3. Orientin has neuroprotection effect by the intracellular mediation of caspase activity; may alleviate cognitive deficits and oxidative stress in AD mice; can exert antidepressant-like effects on CUMS mice, specifically by improving central oxidative stress, neurotransmission, and neuroplasticity.

Formula: C₂₁H₂₀O₁₁

Colore e forma: Solid

Peso molecolare: 448.3769

Ref: TM-TMSM-1796

Orientin

CAS: 28608-75-5

Orientin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₁H₂₀O₁₁

Purezza: (HPLC) ≥99%

Colore e forma: Powder

Peso molecolare: 448.38

Ref: 11-1054S

Orientin

CAS: 28608-75-5

Orientin has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects. Orientin protects H9c2 cardio-mytocytes against I/R-induced apoptosis by modulating the mPTP opening, and this role of orientin may involve the PI3K/Akt signaling pathway; it also can decrease C/EBPα and PPARγ protein expression level in 3T3-L1 cells.

Formula: C₂₁H₂₀O₁₁

Purezza: 95%~99%

Peso molecolare: 448.38

Ref: BP-BP1042

Orientin

Prodotto controllato

CAS: 28608-75-5

Stability Hygroscopic
Applications Orientin is a flavone, a chemical flavonoid compound. Orientin have been investigated for its anti-oxidant, antihypertensive and antihyperlipidemic effects.
References Yao, H., et al.: Food Chem., 135, 2802 (2012); Gordon, A., et al.: Food Chem., 133, 256 (2012); Cermak, R., et al.: Expert. Opin. Drug. Metab. Toxicol., 4, 17 (2008);

Formula: C₂₁H₂₀O₁₁

Colore e forma: Neat

Peso molecolare: 448.38

Ref: TR-O674900

Orientin

CAS: 28608-75-5

1.

Formula: C₂₁H₂₀O₁₁

Purezza: 98.77% - 99.96%

Colore e forma: Yellow Powder

Peso molecolare: 448.3769

Ref: TM-T6S0721

Orientin

CAS: 28608-75-5

Natural glycoside

Formula: C₂₁H₂₀O₁₁

Purezza: ≥ 98.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 448.38

Ref: 5G-89746

Orientin

CAS: 28608-75-5

Orientin (Luteolin-8-C-glucoside) is a flavonoid that has been shown to have biological properties, such as anti-inflammatory and antioxidant activities, which may be due to its ability to inhibit toll-like receptor 4. Orientin is an effective inhibitor of the growth of Leishmania amazonensis in vitro. It also inhibits the growth of Candida glabrata, a fungus that causes oral thrush and other infections. Orientin has been shown to have high values in inflammatory bowel diseases (IBD).

Formula: C₂₁H₂₀O₁₁

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 448.38 g/mol

Ref: 3D-MO08113

Orientin

CAS: 28608-75-5

Formula: C₂₁H₂₀O₁₁

Peso molecolare: 448.4

Ref: BE-RMT12150

Orientin

CAS: 28608-75-5

Formula: C₂₁H₂₀O₁₁

Peso molecolare: 448.4

Ref: BE-RMCO060000

Orientin

CAS: 28608-75-5

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one

Formula: C₂₁H₂₀O₁₁

Purezza: 60% +(HPLC)

Peso molecolare: 448.38

Ref: IN-DG01415500

ORIENTIN

CAS: 28608-75-5

Purezza: 98.0%

Colore e forma: Solid

Peso molecolare: 448.3800049

Ref: 10-F859737

Orientin

CAS: 28608-75-5

Formula: C₂₁H₂₀O₁₁

Peso molecolare: 448.38

Ref: ST-EA-CP-O53000