CAS 2918281-79-3

Formula: C29H31F3N6O4

InChI: InChI=1S/C29H31F3N6O4/c1-28(2,29(30,31)32)25-18-26(37-42-25)34-27(39)33-21-7-3-19(4-8-21)23-17-24(36-35-23)20-5-9-22(10-6-20)41-16-13-38-11-14-40-15-12-38/h3-10,17-18H,11-16H2,1-2H3,(H,35,36)(H2,33,34,37,39)

InChI key: KVGTWUGUDPNRGC-UHFFFAOYSA-N

SMILES: CC(C)(C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CC(=NN3)C4=CC=C(C=C4)OCCN5CCOCC5)C(F)(F)F

RET-IN-22

CAS: 2918281-79-3

RET-IN-22 (compound 17b) is a potent, selective, and orally active inhibitor of RET, exhibiting IC50 values of 20.9 nM for wild-type RET and 18.3 nM for RET-

Formula: C₂₉H₃₁F₃N₆O₄

Colore e forma: Solid

Peso molecolare: 584.59

Ref: TM-T78683