CAS 3023189-40-1

Formula: C26H21ClN6O5S2

InChI: InChI=1S/C26H21ClN6O5S2/c1-32-19-10-6-5-9-17(19)22(15-7-3-2-4-8-15)30-23(24(32)35)31-26(39)40-14-21(34)29-25(36)28-18-13-16(27)11-12-20(18)33(37)38/h2-13,23H,14H2,1H3,(H,31,39)(H2,28,29,34,36)/t23-/m0/s1

InChI key: LWZLLHPZXXUHDA-QHCPKHFHSA-N

SMILES: CN1C2=CC=CC=C2C(=N[C@H](C1=O)NC(=S)SCC(=O)NC(=O)NC3=C(C=CC(=C3)Cl)[N+](=O)[O-])C4=CC=CC=C4

(R)-SL18

CAS: 3023189-40-1

(R)-SL18 is a degrader of ANXA3 that facilitates its breakdown via ubiquitination. This compound can inhibit the proliferation, migration, invasion, and colony formation of breast cancer cells, while also inducing apoptosis. (R)-SL18 is applicable for research in triple-negative breast cancer.

Formula: C₂₆H₂₁ClN₆O₅S₂

Colore e forma: Solid

Peso molecolare: 597.065

Ref: TM-T205446