CAS 303-26-4

Norclorciclizina

Descrizione:

Norclorciclizina, con il numero CAS 303-26-4, è un composto chimico che appartiene alla classe degli antistaminici. È un derivato della ciclizina, utilizzato principalmente per le sue proprietà antiemetiche e antistaminiche. Norclorciclizina mostra una gamma di effetti farmacologici, inclusa la capacità di alleviare i sintomi associati al mal d'auto e alle allergie. Il composto è caratterizzato dalle sue caratteristiche strutturali, che includono un anello di piperazina e un sistema aromatico clorato, contribuendo alla sua attività biologica. Viene tipicamente somministrato in varie formulazioni e la sua efficacia è attribuita alla sua capacità di bloccare i recettori dell'istamina H1. Inoltre, Norclorciclizina può avere effetti sedativi, rendendolo utile in determinati contesti terapeutici. Tuttavia, come molti antistaminici, può anche causare effetti collaterali come sonnolenza, secchezza delle fauci e vertigini. Il suo profilo di sicurezza e farmacocinetica sono considerazioni importanti nell'uso clinico, ed è essenziale attenersi alle dosi raccomandate per minimizzare gli effetti avversi.

Formula: C₁₇H₁₉ClN₂

InChI: InChI=1/C17H19ClN2/c18-16-8-6-15(7-9-16)17(14-4-2-1-3-5-14)20-12-10-19-11-13-20/h1-9,17,19H,10-13H2/p+2/t17-/m0/s1

InChI key: InChIKey=UZKBSZSTDQSMDR-UHFFFAOYSA-N

SMILES: C(C1=CC=C(Cl)C=C1)(C2=CC=CC=C2)N3CCNCC3

Sinonimi:

• (±)-1-(p-Chlorobenzhydryl)piperazine
• 1-(4-Chloro-α-phenylbenzyl)piperazine
• 1-(4-Chlorobenzhydryl)-piperizine
• 1-(4-Chlorophenylmethyl)piperazine
• 1-(α-Phenyl-4-chlorobenzyl)piperazine
• 1-[(4-Chlorophenyl) phenylmethyl] piperazine
• 1-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazinediium
• 1-[(S)-(4-chlorophenyl)(phenyl)methyl]piperazinediium
• 1-[4-Chlorophenyl) (Phenyl)Methyl] Piperazine
• 4-(4-Chlorobenzhydryl)piperazine
• Chlorophenyl)(phenyl)methyl)piperazine,1-((4-
• N-(4-Chlorobenzhydryl)piperazine
• N-(4-Chlorophenyl)phenylmethylpiperazine
• N-(p-Chlorobenzhydryl)-piperazine
• NSC 86164
• Norchlorcyclizine
• Piperazine, 1-(p-chloro-α-phenylbenzyl)-
• Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-
• N-(4-CHLOROBENZYLHYDRYL)PIPERAZINE
• Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-
• 1-((4-chlorophenyl)phenylmethyl)-piperazin
• 1-(4-Chloro-alpha-phenylbenzyl)piperazine
• TIMTEC-BB SBB002998
• 1-(4-CHLOROBENZHYDRYL)PIPERAZINE
• 1-(4-CHLORODIPHENYLMETHYL)-PIPERAZINE
• 1-(p-chloro-alpha-phenylbenzyl)-piperazin
• Piperazine, 1-(alpha-(4-chlorophenyl)benzyl)-
• AKOS BBS-00003606
• 1-(4-CHLOROBENZHYDRYL)PIPERAZINE, TECH.,
• 1-(alpha-Phenyl-4-chlorobenzyl)piperazine
• 1-[(4-CHLORO-PHENYL)-PHENYL-METHYL]-PIPERAZINE

1-[(4-Chlorophenyl)phenylmethyl]piperazine

CAS: 303-26-4

Colore e forma: Neat

Ref: 61-FOR0380.01

CETIRIZINE IMPURITY A CRS

CAS: 303-26-4

CETIRIZINE IMPURITY A CRS

Formula: C₁₇H₁₉ClN₂

Peso molecolare: 286.7992

Ref: 41-C0980651

MECLOZINE IMPURITY H CRS

CAS: 303-26-4

MECLOZINE IMPURITY H CRS

Formula: C₁₇H₁₉ClN₂

Colore e forma: May Be Present In Various Forms. Powder.

Peso molecolare: 286.7992

Ref: 41-Y0001311

Hydroxyzine Related Compound A (1-[(4-Chlorophenyl)phenylmethyl]piperazine)

CAS: 303-26-4

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Formula: C₁₇H₁₉ClN₂

Colore e forma: Powder

Peso molecolare: 286.12368

Ref: 45-1333058

Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-

CAS: 303-26-4

Formula: C₁₇H₁₉ClN₂

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 286.7992

Ref: IN-DA002ZJZ

Norchlorcyclizine, 10mM (in DMSO)

CAS: 303-26-4

Norchlorcyclizine, 10mM (in DMSO)

Purezza: ≥95%

Peso molecolare: 286.8g/mol

Ref: 54-BUP19283

Cetirizine EP Impurity A (Hydroxyzine USP Related Compound A, Levocetirizine EP Impurity I)

CAS: 303-26-4

Formula: C₁₇H₁₉ClN₂

Colore e forma: Off-White Solid

Peso molecolare: 286.80

Ref: 4Z-C-208

1-(4-Chlorobenzhydryl)piperazine

CAS: 303-26-4

Formula: C₁₇H₁₉ClN₂

Purezza: >98.0%(GC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 286.80

Ref: 3B-C1611

(RS)-1-[(4-Chlorophenyl)phenylmethyl]piperazine

Prodotto controllato

CAS: 303-26-4

Formula: C₁₇H₁₉ClN₂

Colore e forma: Neat

Peso molecolare: 286.80

Ref: 86-MM0380.01

Norchlorcyclizine

CAS: 303-26-4

Norchlorcyclizine (C-10) is a partially selective NPR-B inhibitor. It also is an inhibitor of human tyrosyl-DNA phosphodiesterase 1.

Formula: C₁₇H₁₉ClN₂

Purezza: 97.27%

Colore e forma: White Solid

Peso molecolare: 286.8

Ref: TM-T20499

1-(4-Chlorobenzhydryl)piperazine

CAS: 303-26-4

1-(4-Chlorobenzhydryl)piperazine

Purezza: 98%

Peso molecolare: 286.80g/mol

Ref: 54-OR4570

Cetirizine EP Impurity A

CAS: 303-26-4

Formula: C₁₇H₁₉ClN₂

Peso molecolare: 286.79

Ref: ST-EA-CP-C14001

1-[(4-Chlorophenyl)phenylmethyl]piperazine

Prodotto controllato

CAS: 303-26-4

Impurity Hydroxyzine EP Impurity A; Cetirizine Impurity A; Cetirizine USP A
Applications A metabolite of Cetirizine (C281100) and Hydroxyzine. Citirizine impurity A. Hydroxyzine EP Impurity A. Cetirizine Impurity A. Cetirizine USP A.
References Lewis, T., et al.: Bioorg. Med. Chem. Lett., 14, 2265 (2004),

Formula: C₁₇H₁₉ClN₂

Colore e forma: Off White

Peso molecolare: 286.8

Ref: TR-C379575

Buclizine Impurity 2

CAS: 303-26-4

Formula: C₁₇H₁₉ClN₂

Peso molecolare: 286.80

Ref: ST-EA-CP-B30002

1-[(4-Chlorophenyl)(phenyl)methyl]piperazine

CAS: 303-26-4

Purezza: 90.0%

Colore e forma: Solid

Peso molecolare: 286.79998779296875

Ref: 10-F068945

Levocetirizine EP Impurity I

CAS: 303-26-4

Formula: C₁₇H₁₉ClN₂

Peso molecolare: 286.8

Ref: ST-EA-CP-L15001

1-[(4-Chlorophenyl)phenylmethyl]piperazine

Prodotto controllato

CAS: 303-26-4

1-[(4-Chlorophenyl)phenylmethyl]piperazine is an analytical reagent that is used in the determination of meclozine, a drug used for the treatment of nausea and vomiting. 1-[(4-Chlorophenyl)phenylmethyl]piperazine is a nucleophile, which means that it can donate electrons to other molecules. It can be used as a catalyst to increase the rate of chemical reactions. 1-[(4-Chlorophenyl)phenylmethyl]piperazine may also be used in wastewater treatment because it has been shown to have phospholipidosis inhibiting properties. The levorotatory form (1R-enantiomer) of this compound has been shown to inhibit protein synthesis in vitro and is an amine oxidase inhibitor that binds to proteins with nitrogen atoms. This nucleophilic compound may also be converted into an n-oxide or dinucleotide phosphate by hydrochloric acid and

Formula: C₁₇H₁₉ClN₂

Purezza: Min. 95%

Peso molecolare: 286.8 g/mol

Ref: 3D-FC20350