CAS 303-26-4
:Norclorciclizina
Descrizione:
Norclorciclizina, con il numero CAS 303-26-4, è un composto chimico che appartiene alla classe degli antistaminici. È un derivato della ciclizina, utilizzato principalmente per le sue proprietà antiemetiche e antistaminiche. Norclorciclizina mostra una gamma di effetti farmacologici, inclusa la capacità di alleviare i sintomi associati al mal d'auto e alle allergie. Il composto è caratterizzato dalle sue caratteristiche strutturali, che includono un anello di piperazina e un sistema aromatico clorato, contribuendo alla sua attività biologica. Viene tipicamente somministrato in varie formulazioni e la sua efficacia è attribuita alla sua capacità di bloccare i recettori dell'istamina H1. Inoltre, Norclorciclizina può avere effetti sedativi, rendendolo utile in determinati contesti terapeutici. Tuttavia, come molti antistaminici, può anche causare effetti collaterali come sonnolenza, secchezza delle fauci e vertigini. Il suo profilo di sicurezza e farmacocinetica sono considerazioni importanti nell'uso clinico, ed è essenziale attenersi alle dosi raccomandate per minimizzare gli effetti avversi.
Formula:C17H19ClN2
InChI:InChI=1/C17H19ClN2/c18-16-8-6-15(7-9-16)17(14-4-2-1-3-5-14)20-12-10-19-11-13-20/h1-9,17,19H,10-13H2/p+2/t17-/m0/s1
InChI key:InChIKey=UZKBSZSTDQSMDR-UHFFFAOYSA-N
SMILES:C(C1=CC=C(Cl)C=C1)(C2=CC=CC=C2)N3CCNCC3
Sinonimi:- (±)-1-(p-Chlorobenzhydryl)piperazine
- 1-(4-Chloro-α-phenylbenzyl)piperazine
- 1-(4-Chlorobenzhydryl)-piperizine
- 1-(4-Chlorophenylmethyl)piperazine
- 1-(α-Phenyl-4-chlorobenzyl)piperazine
- 1-[(4-Chlorophenyl) phenylmethyl] piperazine
- 1-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazinediium
- 1-[(S)-(4-chlorophenyl)(phenyl)methyl]piperazinediium
- 1-[4-Chlorophenyl) (Phenyl)Methyl] Piperazine
- 4-(4-Chlorobenzhydryl)piperazine
- Chlorophenyl)(phenyl)methyl)piperazine,1-((4-
- N-(4-Chlorobenzhydryl)piperazine
- N-(4-Chlorophenyl)phenylmethylpiperazine
- N-(p-Chlorobenzhydryl)-piperazine
- NSC 86164
- Norchlorcyclizine
- Piperazine, 1-(p-chloro-α-phenylbenzyl)-
- Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-
- N-(4-CHLOROBENZYLHYDRYL)PIPERAZINE
- Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-
- 1-((4-chlorophenyl)phenylmethyl)-piperazin
- 1-(4-Chloro-alpha-phenylbenzyl)piperazine
- TIMTEC-BB SBB002998
- 1-(4-CHLOROBENZHYDRYL)PIPERAZINE
- 1-(4-CHLORODIPHENYLMETHYL)-PIPERAZINE
- 1-(p-chloro-alpha-phenylbenzyl)-piperazin
- Piperazine, 1-(alpha-(4-chlorophenyl)benzyl)-
- AKOS BBS-00003606
- 1-(4-CHLOROBENZHYDRYL)PIPERAZINE, TECH.,
- 1-(alpha-Phenyl-4-chlorobenzyl)piperazine
- 1-[(4-CHLORO-PHENYL)-PHENYL-METHYL]-PIPERAZINE
- Vedi altri sinonimi
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1-(4-Chlorobenzhydryl)piperazine
CAS:Formula:C17H19ClN2Purezza:>98.0%(GC)Colore e forma:White to Almost white powder to crystalPeso molecolare:286.80MECLOZINE IMPURITY H CRS
CAS:MECLOZINE IMPURITY H CRSFormula:C17H19ClN2Colore e forma:May Be Present In Various Forms. Powder.Peso molecolare:286.7992Hydroxyzine Related Compound A
CAS:Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoiFormula:C17H19ClN2Colore e forma:PowderPeso molecolare:286.12368Norchlorcyclizine, 10mM (in DMSO)
CAS:Norchlorcyclizine, 10mM (in DMSO)Formula:C17H19ClN2Purezza:≥95%, 10 mM in DMSOPeso molecolare:286.8Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-
CAS:Formula:C17H19ClN2Purezza:95%Colore e forma:SolidPeso molecolare:286.7992Cetirizine EP Impurity A (Levocetirizine EP Impurity I, Meclozine EP Impurity H, Hydroxyzine EP Impurity A, Hydroxyzine USP Related Compound A)
CAS:Formula:C17H19ClN2Colore e forma:Off-White SolidPeso molecolare:286.80(RS)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
CAS:Prodotto controllatoFormula:C17H19ClN2Colore e forma:NeatPeso molecolare:286.801-[(4-Chlorophenyl)phenylmethyl]piperazine
CAS:Prodotto controllatoImpurity Hydroxyzine EP Impurity A; Cetirizine Impurity A; Cetirizine USP A
Applications A metabolite of Cetirizine (C281100) and Hydroxyzine. Citirizine impurity A. Hydroxyzine EP Impurity A. Cetirizine Impurity A. Cetirizine USP A.
References Lewis, T., et al.: Bioorg. Med. Chem. Lett., 14, 2265 (2004),Formula:C17H19ClN2Colore e forma:NeatPeso molecolare:286.8Norchlorcyclizine
CAS:Norchlorcyclizine (C-10) is a partially selective NPR-B inhibitor. It also is an inhibitor of human tyrosyl-DNA phosphodiesterase 1.Formula:C17H19ClN2Purezza:97.27%Colore e forma:SolidPeso molecolare:286.7991-(4-Chlorobenzhydryl)piperazine
CAS:1-(4-Chlorobenzhydryl)piperazineFormula:C17H19ClN2Purezza:>98%Colore e forma:LiquidPeso molecolare:286.79916Ref: ST-EA-CP-L15001
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-B30002
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta1-[(4-Chlorophenyl)(phenyl)methyl]piperazine
CAS:Formula:C17H19ClN2Purezza:90.0%Colore e forma:SolidPeso molecolare:286.81-[(4-Chlorophenyl)phenylmethyl]piperazine
CAS:Prodotto controllato1-[(4-Chlorophenyl)phenylmethyl]piperazine is an analytical reagent that is used in the determination of meclozine, a drug used for the treatment of nausea and vomiting. 1-[(4-Chlorophenyl)phenylmethyl]piperazine is a nucleophile, which means that it can donate electrons to other molecules. It can be used as a catalyst to increase the rate of chemical reactions. 1-[(4-Chlorophenyl)phenylmethyl]piperazine may also be used in wastewater treatment because it has been shown to have phospholipidosis inhibiting properties. The levorotatory form (1R-enantiomer) of this compound has been shown to inhibit protein synthesis in vitro and is an amine oxidase inhibitor that binds to proteins with nitrogen atoms. This nucleophilic compound may also be converted into an n-oxide or dinucleotide phosphate by hydrochloric acid and
Formula:C17H19ClN2Purezza:Min. 95%Peso molecolare:286.8 g/molRef: 3D-FC20350
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